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European Journal of Medical Research

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Open Access 01-12-2023 | Ultrasound | Research

Blood flow on ultrasound imaging is a predictor of lump margin status in breast-conserving patients: a retrospective matching study

Authors: Rong Zhao, Jianyong Zhang, Jinnan Gao

Published in: European Journal of Medical Research | Issue 1/2023

Abstract

Purpose

This study investigated the relationship between breast ultrasound features and lump margin status in breast-conserving patients.

Methods

A single-institution database and medical records system were searched to identify patients who had undergone breast-conserving surgery between 2015 and 2022. Patients were divided into case and control groups based on their postoperative margin status, and different matching methods [case–control matching (CCM) and propensity score matching (PSM)] were used to match the cases and controls at a ratio of 1:1.

Results

Before matching, patients with positive margins were more likely to have a tumor with increased blood flow (OR = 2.90, 95% CI 1.83–4.61, p < 0.001) and microcalcifications (OR = 2.22, 95% CI 1.44–3.42, p < 0.001). Among the 83 pairs of CCM subjects, patients with positive margins were prone to increased blood flow (p = 0.007) and crab sign (p = 0.040). In addition, there was a significant difference in blood flow (p = 0.030) among PSM subjects. After adjusting for the unbalanced factors, the same results were obtained.

Conclusions

Ultrasound blood flow significantly predicts the status of breast-conserving margins, but further studies are required to verify our findings.

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Title: Blood flow on ultrasound imaging is a predictor of lump margin status in breast-conserving patients: a retrospective matching study
Authors: Rong Zhao
Jianyong Zhang
Jinnan Gao
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Ultrasound
Ultrasound
Breast Cancer
Breast Cancer
Published in: European Journal of Medical Research / Issue 1/2023
Electronic ISSN: 2047-783X
DOI: https://doi.org/10.1186/s40001-023-01356-4

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Blood flow on ultrasound imaging is a predictor of lump margin status in breast-conserving patients: a retrospective matching study

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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