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Published in: European Journal of Clinical Microbiology & Infectious Diseases 1/2020

01-01-2020 | Toxoplasmosis | Review

Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals

Authors: Amjad Hayat Khan, Rahmah Noordin

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 1/2020

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Abstract

Infection by Toxoplasma gondii is prevalent worldwide. The parasite can infect a broad spectrum of vertebrate hosts, but infection of fetuses and immunocompromised patients is of particular concern. Easy-to-perform, robust, and highly sensitive and specific methods to detect Toxoplasma infection are important for the treatment and management of patients. Rapid diagnostic methods that do not sacrifice the accuracy of the assay and give reproducible results in a short time are highly desirable. In this context, rapid diagnostic tests (RDTs), especially with point-of-care (POC) features, are promising diagnostic methods in clinical microbiology laboratories, especially in areas with minimal laboratory facilities. More advanced methods using microfluidics and sensor technology will be the future trend. In this review, we discuss serological and molecular-based rapid diagnostic tests for detecting Toxoplasma infection in humans as well as animals.
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Metadata
Title
Serological and molecular rapid diagnostic tests for Toxoplasma infection in humans and animals
Authors
Amjad Hayat Khan
Rahmah Noordin
Publication date
01-01-2020
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Clinical Microbiology & Infectious Diseases / Issue 1/2020
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-019-03680-2

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