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Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Solid Tumor Skin Cancer

Skin Cancer
23-04-2024 Checkpoint Inhibitors News

Some reassurance on ICI use in pregnancy from VigiBase analysis

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A study has found little over-reporting of adverse maternofetal outcomes among pregnant women with cancer using ICIs versus other anticancer agents.

Editor's Choice

Primary melanoma of the lung

Open Access Melanoma Case Study

A report of primary endobronchial melanoma that sheds light on the clinical presentation, histopathology, diagnostic challenges, and treatment options for this rare entity.

Individualized neoantigen therapy may benefit people with resected melanoma

25-01-2024 Melanoma News

Adding a novel mRNA-based individualized neoantigen therapy to adjuvant pembrolizumab could improve the outcomes of patients with completely resected melanoma.

Treatment of melanoma brain and leptomeningeal metastases

Melanoma Review

The past decade has seen significant advancements in the treatment of melanoma brain and leptomeningeal metastases. The sequence of therapies depends on factors such as the number and size of metastases, status of systemic disease control, and neurological symptoms.

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Latest News

Some reassurance on ICI use in pregnancy from VigiBase analysis

23-04-2024 Checkpoint Inhibitors News

Smoking linked to worse melanoma survival

09-02-2024 Melanoma News

Individualized neoantigen therapy may benefit people with resected melanoma

25-01-2024 Melanoma News

Genetic counseling ‘should be considered’ for patients with early-onset MCC

05-01-2024 Merkel Cell Carcinoma News

Encephalopathy is the predominant neurological irAE due to checkpoint inhibitors

13-12-2023 Encephalopathy News

Emotional distress linked to poor neoadjuvant immunotherapy outcomes

24-11-2023 Melanoma News
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

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Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine

Case Studies

Primary melanoma of the lung

Open Access Melanoma Case Study

A report of primary endobronchial melanoma that sheds light on the clinical presentation, histopathology, diagnostic challenges, and treatment options for this rare entity.

Primary melanoma presenting in the cervical spine

Open Access Melanoma Case Study

When primary CNS melanoma has a spinal location, it typically manifests in the thoracic sections. This case report describes a patient with an uncommon presentation in the cervical spine. 

Current Reviews

A Practical Review of Encorafenib and Binimetinib Therapy Management in Patients with BRAF V600E-Mutant Metastatic Non-Small Cell Lung Cancer

Open Access NSCLC Review

According to current guidelines, targeted therapy with a combination of BRAF plus MEK inhibitors is the preferred first-line treatment for patients with BRAF V600E-mutant metastatic non-small cell lung cancer (NSCLC). In the open-label …

Review of the application of the most current sophisticated image processing methods for the skin cancer diagnostics purposes

Skin Cancer Review

This paper presents the most current and innovative solutions applying modern digital image processing methods for the purpose of skin cancer diagnostics. Skin cancer is one of the most common types of cancers. It is said that in the USA only, one …

Systematic review of randomized controlled trials of topicals for actinic keratosis field therapy

Actinic Keratosis REVIEW

Cutaneous field cancerization in dermatology describes the anatomic region of photodamaged skin with actinic keratoses (AKs) or cutaneous squamous cell carcinoma (cSCC) that is surrounded by cellular atypia, forming a dysplastic field. The concept …

Skin color reporting in squamous cell carcinoma-related randomized controlled trials in top dermatology journals: a systematic review

Open Access Skin Cancer REVIEW

The objectives are to determine the frequency that skin color is reported in randomized controlled trials (RCTs) involving squamous cell carcinoma (SCC) detection and treatment in leading dermatology journals. A systematic review of RCTs involving …

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

CME & eLearning

Cases

Oncology and Hematology

Take on interactive case studies with a focus on hematology. Each case has been prepared by renowned experts in the field and features knowledge-check questions with answers to help keep you and your practice up to date.

Developed by: Springer Medizin
Webinar | 16-05-2023 | 17:30 (CEST)

Keynote webinar | Spotlight on cardio-oncology

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An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Prof. Rudolf de Boer
Prof. Lorenz Lehmann
Dr. Teresa Lopéz Fernández
Developed by: Springer Medicine

Further Reading

A Practical Review of Encorafenib and Binimetinib Therapy Management in Patients with BRAF V600E-Mutant Metastatic Non-Small Cell Lung Cancer

Open Access NSCLC Review

According to current guidelines, targeted therapy with a combination of BRAF plus MEK inhibitors is the preferred first-line treatment for patients with BRAF V600E-mutant metastatic non-small cell lung cancer (NSCLC). In the open-label …

Skin color reporting in squamous cell carcinoma-related randomized controlled trials in top dermatology journals: a systematic review

Open Access Skin Cancer REVIEW

The objectives are to determine the frequency that skin color is reported in randomized controlled trials (RCTs) involving squamous cell carcinoma (SCC) detection and treatment in leading dermatology journals. A systematic review of RCTs involving …

Frequency and characteristics of immune-related thyroid adverse events in patients with resected stage III/IV melanoma treated with adjuvant PD-1 inhibitors: a national cohort study

Open Access Melanoma Research

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy and improved the treatment of patients with melanoma [ 1 ]. The most important immune checkpoint targets are cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death …

Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model

Open Access Melanoma Research

During the past decade, the field of immuno-oncology has dramatically advanced. Variety of immunotherapy approaches are introduced to the clinic to enhance durable immunity against solid tumours. However, high immunotoxicity and low immunogenicity …

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