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Retinal Diseases 

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  1. Open Access 01-12-2024 | Retinal Diseases | OriginalPaper

    The socioeconomic epidemiology of inherited retinal diseases in Portugal

    Inherited retinal diseases (IRDs) are a group of rare degenerative disorders of the retina, with clinical and genetic heterogeneity that can lead to blindness from birth to late middle age [ 1 , 2 ]. Economic costs and reduction in the quality of …

  2. Open Access 01-12-2024 | Retinal Diseases | ReviewPaper

    Cost-of-illness studies of inherited retinal diseases: a systematic review

    Inherited retinal diseases (IRDs), also called hereditary retinal dystrophies, are a heterogeneous group of orphan genetic disorders that usually lead to severe vision impairment or blindness in infancy, childhood or adulthood [ 1 , 2 ]. IRDs are …

  3. Open Access 01-12-2024 | OriginalPaper

    Incidence rates of retinal vascular occlusive diseases from 2011 to 2020 in South Korea: a nationwide cohort study

    Retinal vascular occlusions, including retinal vein occlusion (RVO) and retinal artery occlusion (RAO), are common causes of visual impairment. The two forms of occlusion have different pathophysiology, systemic implications, and management; …

  4. Open Access 01-12-2024 | Syphilis | OriginalPaper

    Ocular syphilis masquerading as refractory retinal diseases

    The spirochete bacterium Treponema pallidum causes infection known as syphilis [ 1 ]. Given that it is known as ‘the great imitator’ for its ability to mimic many diseases [ 2 ] and its diagnosis is dependent on laboratory findings, screening for …

  5. 10-11-2023 | Retinal Diseases | OriginalPaper

    Whole genome sequencing for inherited retinal diseases in the Korean National Project of Bio Big Data

    Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of diseases characterized by the progressive loss of photoreceptors and/or retinal pigment epithelial cells [ 1 – 3 ] that affect approximately 1 in 2000–3000 …

  6. 01-12-2024 | Diabetic Retinopathy | ReviewPaper

    Clinical utility of handheld fundus and smartphone-based camera for monitoring diabetic retinal diseases: a review study

    Diabetic retinopathy (DR) is the leading global cause of vision loss, accounting for 4.8% of global blindness cases as estimated by the World Health Organization (WHO). Fundus photography is crucial in ophthalmology as a diagnostic tool for …

  7. 27-01-2024 | Laser | Online First

    Subthreshold laser treatment in retinal diseases: a mini review

    Subthreshold laser treatment (STL) is a newly adopted treatment modality introduced for the treatment of retinal diseases. Up to date, clear recommendations for the use of STL in specific clinical entities have not been formulated; thus, its use …

  8. Open Access 01-12-2024 | Retinal Diseases | ReviewPaper

    Noninvasive electrical stimulation as a neuroprotective strategy in retinal diseases: a systematic review of preclinical studies

    Since the eighteenth century, there has been great enthusiasm and curiosity in studying the effects of electrical currents inside the human body [ 1 ]. Electrical activity has a crucial impact on the development and survival of neurons [ 2 – 4 ] …

  9. Open Access 19-12-2023 | Gene Therapy in Oncology | ReviewPaper

    Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond

    This comprehensive review provides a thorough examination of inherited retinal diseases (IRDs), encompassing their classification, genetic underpinnings, and the promising landscape of gene therapy trials. IRDs, a diverse group of genetic …

  10. Open Access 09-11-2023 | Peeling | OriginalPaper

    Long-Term Quantitative Analysis of Inner Retinal Dimples and Visual Function Post Internal Limiting Membrane Peeling in Macular Diseases

    Internal limiting membrane (ILM) peeling provides promising therapeutic outcomes in macular disease, such as increasing the closure rate of idiopathic macular hole (iMH), reducing the recurrence of idiopathic epiretinal membrane (iERM), assisting …

  11. Open Access 25-10-2023 | Diabetic Retinopathy | ReviewPaper

    AAV-Based Strategies for Treatment of Retinal and Choroidal Vascular Diseases: Advances in Age-Related Macular Degeneration and Diabetic Retinopathy Therapies

    Age-related macular degeneration (AMD) and diabetic retinopathy (DR) are vascular diseases with high prevalence, ranking among the leading causes of blindness and vision loss worldwide. Despite being effective, current treatments for AMD and DR …

  12. Open Access 01-12-2023 | Folic Acid | ReviewPaper

    Folate and retinal vascular diseases

    Folate, a pteroylglutamic acid derivative, participates in fundamental cellular metabolism. Homocysteine, an amino acid, serves as an intermediate of the methionine cycle and can be converted back to methionine. Hyperhomocysteinemia is a …

  13. Open Access 01-12-2023 | Pigmentary Retinopathy | OriginalPaper

    Prevalence of inherited retinal diseases in a large Egyptian cohort

    Inherited retinal diseases (IRDs) form a rare, highly heterogeneous group of genetic disorders characterized by retinal degeneration. Many subtypes exist where the classification is usually difficult, complex and variable according to the mode of …

  14. Open Access 11-07-2023 | Edema | OriginalPaper

    Incidence and treatment approach of intraocular pressure elevation after various types of local steroids for retinal diseases

    Glaucoma is considered to be the second leading cause of visual impairment and blindness worldwide, affecting about 70 million people [ 1 ]. The most common form of this disease, concerning 70% of cases, is primary open-angle glaucoma [ 2 ]. A …

  15. Open Access 18-03-2023 | Photodynamic Therapy | ReviewPaper

    Yellow Subthreshold Micropulse Laser in Retinal Diseases: An In-Depth Analysis and Review of the Literature

    Yellow subthreshold micropulse laser (YSML) is a retinal laser capable of inducing a biologic response without causing thermal damage to the targeted tissue. The 577-nm YSML is delivered to the retina abiding by different protocols in which …

  16. Open Access 04-11-2022 | Diabetic Retinopathy | ReviewPaper

    The Role of Angiopoietins in Neovascular Diabetes-Related Retinal Diseases

    Diabetic retinopathy is a devastating and frequent complication of poorly controlled diabetes, whose pathogenesis is still only partially understood. Advances in basic research over the last two decades have led to the discovery of angiopoietins …

  17. 09-03-2023 | Pigmentary Retinopathy | OriginalPaper

    Electronic medical records driven big data analytics in retinal diseases, report number 1: non-oncological retinal diseases in children and adolescents in India

    Retinal diseases constitute a significant cause of childhood and adolescent vision impairment (VI) and blindness [ 1 , 2 ]. In population-based studies, the prevalence is 3–22% in children in India. [ 1 , 2 ]. In the past three decades, there has …

  18. Open Access 27-06-2023 | Artificial Intelligence | OriginalPaper

    Patients’ Perception of Robot-Driven Technology in the Management of Retinal Diseases

    Artificial intelligence-driven technologies are being rapidly integrated into diagnostics and interventional ophthalmological medicine [ 1 ]. We are now seeing the application of robots in facilitating both the diagnosis of retinal diseases [ 2 ] …

  19. 08-06-2023 | Diabetic Retinopathy | OriginalPaper

    EyeCNN: exploring the potential of convolutional neural networks for identification of multiple eye diseases through retinal imagery

    Our sense of sight is crucial for perceiving the world around us, as it allows us to take in about 80% of the information we receive. Taking care of our eyes can help prevent vision loss and blindness, as well as conditions such as cataracts and …

  20. Open Access 01-06-2022 | Retinal Diseases | ReviewPaper

    An Introduction to Biosimilars for the Treatment of Retinal Diseases: A Narrative Review

    Biological therapies have revolutionized the treatment of disease across a number of therapeutic areas including retinal diseases. However, on occasion, such treatments may be relatively more expensive compared to small molecule therapies. This …

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