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Progestin 

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  1. 13-05-2024 | Progestin | Online First

    Correction: GnRH antagonist protocol versus progestin-primed ovarian stimulation in patients with polycystic ovary syndrome: a systematic review and meta-analysis

  2. 19-03-2024 | Progestin | Online First

    Metformin and progestins in women with atypical hyperplasia or endometrial cancer: systematic review and meta-analysis

    Endometrial cancer (EC) is one of the most commonly diagnosed cancer types, ranked seventh and fourth places among all female cancers worldwide and in Europe, respectively. Despite the fact that it is predominantly a disease of postmenopausal …

  3. Open Access 01-12-2024 | Desogestrel | Letter

    Higher baseline heart rate variability in CCHS patients with progestin-associated recovery of hypercapnic ventilatory response

    After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took desogestrel, we aimed to evaluate the ventilatory response to hypercapnia of five CCHS patients with …

  4. Open Access 01-12-2024 | OriginalPaper

    Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice

    Granulosa cells (GCs) play a crucial role in follicular development and the maintenance of ovarian function [ 1 ]. Dysregulation of genes associated with GCs function and apoptosis can result in ovarian insufficiency [ 2 , 3 ]. Previous studies …

  5. 13-11-2023 | Ovarian Hyperstimulation Syndrome | ReviewPaper

    GnRH antagonist protocol versus progestin-primed ovarian stimulation in patients with polycystic ovary syndrome: a systematic review and meta-analysis

    Polycystic ovarian syndrome (PCOS) refers to a prevalent endocrine disorders among 6–7% reproductive-aged women around the world. It can result in infertility and other relevant morbidities, and it has triggered a large economic burden that can be …

  6. Open Access 01-12-2023 | ICSI | OriginalPaper

    Nomogram to predict FSH starting dose in poor ovarian response women in progestin primed ovarian stimulation protocol

    Prediction of individual ovarian response to exogenous gonadotropin is a cornerstone for success and safety in all controlled ovarian stimulation (COS) protocols. Providing the best FSH starting dose according to each woman’s own characteristics …

  7. Open Access 01-12-2023 | Infertility | OriginalPaper

    Analysis of euploidy rates in preimplantation genetic testing for aneuploidy cycles with progestin-primed versus GnRH agonist/antagonist protocol

    Ovarian stimulation is a crucial step in assisted reproductive technology (ART), aiming to collect multiple oocytes and generate a sufficient number of embryos available for transfer [ 1 ]. Conventional ovarian stimulation protocols include the …

  8. 31-05-2023 | Progestin | EditorialNotes

    On pills, progestins, and sentinels of progress in reproductive health

  9. 01-07-2023 | Ovarian Cancer | OriginalPaper

    In vitro chemo-preventive efficacy of synthetic progestin Norethindrone in human epithelial ovarian cancer

    Progestin-only based oral contraceptives are majorly used as ‘minipill’ to prevent unintended pregnancy and treat conditions like polycystic ovary syndrome, hirsutism, and acne. However, the dearth of literature has constrained our comprehension …

  10. Open Access 01-09-2022 | Ethinylestradiol | ReviewPaper

    Efficacy of Low-Dose Estrogen–Progestins and Progestins in Japanese Women with Dysmenorrhea: A Systematic Review and Network Meta-analysis

    Dysmenorrhea is common in women of reproductive age and is characterized by symptoms including low abdominal pain, bloating, nausea, vomiting, headache, and dizziness during the menstrual period that have negative effects on quality of life (QoL) …

  11. Open Access 01-12-2023 | Endometriosis | OriginalPaper

    Tolerability of endometriosis medical treatment: a comparison between combined hormonal contraceptives and progestins

    Endometriosis is a chronic inflammatory disease that occurs in women of reproductive age. Much of the treatment involves hormone therapy that suppresses the proliferation of endometriosis lesions.Objective To compare discontinuation rates of …

  12. 13-05-2023 | Progestin | OriginalPaper

    Comparison of fixed and flexible progestin-primed ovarian stimulation protocols to prevent premature luteinization in patients with diminished ovarian reserve

    Progestin-primed ovarian stimulation (PPOS) protocols are used as an alternative to Gonadotropin Releasing Hormone (GnRH) antagonists for pituitary suppression for the last few years. Oral administration and lower costs of progestins are …

  13. Open Access 01-12-2022 | Fertility | OriginalPaper

    Usefulness of random-start progestin-primed ovarian stimulation for fertility preservation

    In fertility-preserving treatment, oocytes should be collected within 2 to 3 weeks after the patient examination to avoid delaying the start of treatment for the underlying disease [ 1 ]. Therefore it is better to start ovarian stimulation as soon …

  14. Open Access 01-12-2023 | Preimplantation Genetic Diagnostics | OriginalPaper

    Progestin Primed Ovarian Stimulation (PPOS) protocol yields lower euploidy rate in older patients undergoing IVF

    Controlled ovarian hyperstimulation (COH), which involves the administration of exogenous gonadotropins to stimulate ovarian follicle growth, is a crucial checkpoint of the in vitro fertilization (IVF)/artificial reproductive technology (ART) …

  15. Open Access 01-12-2022 | Endometriosis | OriginalPaper

    Progestins in the symptomatic management of endometriosis: a meta-analysis on their effectiveness and safety

    Endometriosis is a chronic condition defined by the presence of endometrial-like tissue outside the uterus in the ovaries, the rectovaginal septum, and the pelvic peritoneum [ 1 ]. The disease occurs globally and more commonly affects women of …

  16. Open Access 01-12-2022 | Medroxyprogesterone Acetate | OriginalPaper

    Progestin-primed ovarian stimulation protocol with or without clomiphene citrate for poor ovarian responders: a retrospective cohort study

    Poor ovarian response (POR) indicates that the diminished ovarian reserve or poor response to ovarian stimulation, remains a challenge for both clinicians and patients in IVF/ICSI, which occurs in 5.6–35.1% of ovarian induction cycles [ 1 ]. These …

  17. 06-09-2022 | Meningioma | OriginalPaper

    Meningioma in patients exposed to progestin drugs: results from a real-life screening program

    Meningiomas are the most common primary tumors of the central nervous system [ 1 ]. Risk factors for meningioma include age, female sex, personal history of cranial radiation, family history of meningiomas, and type II neurofibromatosis [ 2 ]. The …

  18. 15-06-2022 | Portal Vein Thrombosis | Report

    Isolated portal vein thrombus due to contraceptive low-dose estrogen progestin use

  19. 11-07-2023 | Dementia | News | Article

    Estrogen–progestin menopausal therapy linked to dementia risk

    They also note that there was no increased risk for dementia with the use of progestin only and vaginal estrogen only therapies.

  20. Open Access 01-12-2022 | Contraception | OriginalPaper

    Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): a prospective cohort study protocol

    Approximately 40% of all pregnancies worldwide are unintended, with an estimated 50% ending in abortion [ 1 ]. Contraception reduces infant mortality, empowers women, enhances educational attainment, reduces the burden of unintended pregnancy, and …

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