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Parkinson's Disease 

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  1. 24-01-2024 | Progressive Supranuclear Palsy | OriginalPaper

    Free water imaging in Parkinson’s disease and atypical parkinsonian disorders

    Parkinson’s disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) are neurodegenerative disorders with parkinsonism as a primary clinical feature [ 1 ]. Although there are certain features specific to each disorder …

  2. 20-04-2024 | Parkinson's Disease | Online First

    Epidemiology of Parkinson’s Disease: An Update

    Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition. The disease was first described in the 19 th century [ 1 ] and is clinically characterized by asymmetric-onset tremor, bradykinesia, rigidity, and postural …

  3. 16-04-2024 | Parkinson's Disease | Online First

    Does Parkinson’s disease affect sleep quality?

    Parkinson’s disease (PD) is a rapidly expanding neurological condition worldwide [ 1 ] and is estimated to be the second most prevalent neurodegenerative disease worldwide; approximately 6.1 million people were documented to have PD in 2016 [ 2 ].

  4. Open Access 01-12-2024 | Parkinson's Disease | OriginalPaper

    Duration, numerosity and length processing in healthy ageing and Parkinson’s disease

    People constantly process temporal, numerical, and length information in everyday activities and interactions with the environment. However, it is unclear whether quantity perception changes during ageing. Previous studies have provided …

  5. Open Access 26-04-2024 | Online First

    Renin-angiotensin system inhibitor use and risk of Parkinson’s disease: a meta-analysis

    Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder characterized by symptoms such as tremor, muscle rigidity, bradykinesia, and postural instability [ 1 ]. It is the predominant movement disorder among the elderly …

  6. 23-04-2024 | Parkinson's Disease | Online First

    Sympathetic dysfunction as an early indicator of autonomic involvement in Parkinson’s disease

    Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms [ 1 – 5 ]. Early detection of prodromal symptoms in PD, prior to the onset of evident cardinal motor symptoms, is crucial for …

  7. Open Access 23-04-2024 | Parkinson's Disease | Online First

    Gait asymmetry and symptom laterality in Parkinson’s disease: two of a kind?

    Asymmetry of motor symptoms is characteristic for Parkinson’s disease (PD) and is particularly observed in the early disease stages. However, asymmetry of symptoms is thought to persist during the entire course of the disease, even if to a lesser …

  8. Open Access 25-04-2024 | Parkinson's Disease | Online First

    Clinical and Brain Morphometry Predictors of Deep Brain Stimulation Outcome in Parkinson’s Disease

    Subthalamic deep brain stimulation (STN-DBS) is known to improve motor function in advanced Parkinson’s disease (PD) and to enable a reduction of anti-parkinsonian medication. While the levodopa challenge test and disease duration are considered …

  9. 24-04-2024 | Parkinson's Disease | Online First

    GBA moderates cognitive reserve's effect on cognitive function in patients with Parkinson's disease

    Parkinson's disease (PD) is a prevalent neurodegenerative disorder [ 1 ] and is characterized by motor symptoms resulting from dopamine deficiency in the basal ganglia [ 2 ] and non-motor manifestations [ 3 , 4 ], such as sleep disturbances [ 5 , 6 …], cognitive impairment [

  10. Open Access 01-12-2024 | Overactive Bladder | OriginalPaper

    Unraveling the interplay between dyskinesia and overactive bladder symptoms in Parkinson’s disease: a comprehensive cohort study based on the long-term follow-up database of Parkinson’s disease

    Parkinson’s disease (PD) is a common neurodegenerative disorder and is characterized by motor and non-motor dysfunction [ 1 ], defined by the gradual and progressive loss of dopaminergic neurons in the substantia nigra that supply the striatum [ 2 …

  11. 15-03-2024 | Parkinson's Disease | Letter

    Contribution of ChatGPT in Parkinson’s Disease Detection

  12. Open Access 01-12-2024 | Parkinson's Disease | ReviewPaper

    The role of the brain renin-angiotensin system in Parkinson´s disease

    The renin-angiotensin system (RAS) was classically considered a circulating hormonal system that regulates blood pressure. However, different tissues and organs, including the brain, have a local paracrine RAS. Mutual regulation between the …

  13. Open Access 25-04-2024 | Parkinson's Disease | Online First

    Altered domain-specific striatal functional connectivity in patients with Parkinson’s disease and urinary symptoms

    Urinary symptoms are frequent in Parkinson’s disease (PD), with patients experiencing both storage and voiding difficulties, such as urgency, incontinence, polyuria, nicturia and voiding hesitancy (Chaudhuri and Schapira 2009 ; Picillo et al. 2017 …

  14. Open Access 23-04-2024 | Respiratory Microbiota | Online First

    Modulation of Gut Microbiota Through Dietary Intervention in Neuroinflammation and Alzheimer’s and Parkinson’s Diseases

    Neurodegenerative diseases cause progressive deterioration in cognitive function by the loss of the activity of neurons in the brain. Worldwide, 10.2 million people suffer from neurodegenerative disorders, and the incidence is steadily increasing.

  15. Open Access 01-12-2024 | Parkinson's Disease | OriginalPaper

    Trends in parkinson’s disease mortality in China from 2004 to 2021: a joinpoint analysis

    Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide and is characterized by the loss of dopaminergic neurons in the substantia nigra and other brain regions [ 1 – 2 ]. Generally, neurological diseases are the …

  16. 25-04-2024 | Parkinson's Disease | Online First

    Hypotensive episodes at 24-h ambulatory blood pressure monitoring predict adverse outcomes in Parkinson’s disease

    Orthostatic hypotension (OH) may affect at least 30% of patients with Parkinson’s disease (PD) [ 1 – 3 ], potentially resulting in dramatic complications, such as falls, fractures, head trauma, wheelchair/bed confinement, and hospitalization, with …

  17. Open Access 13-04-2024 | Deep Brain Stimulation | Online First

    Advanced therapies in Parkinson’s disease: an individualized approach to their indication

    Device aided therapies (DAT) comprising the intrajejunal administration of levodopa/carbidopa intestinal gel (LCIG) and levodopa/carbidopa/entacapone intestinal gel (LECIG), the continuous subcutaneous application of foslevodopa/foscarbidopa or …

  18. Open Access 11-04-2024 | Parkinson's Disease | Online First

    Parkinson's disease and vitamins: a focus on vitamin B12

    Parkinson’s disease (PD) has been linked to a vast array of vitamins among which vitamin B12 (Vit B12) is the most relevant and often investigated specially in the context of intrajejunal levodopa infusion therapy. Vit B12 deficiency, itself, has …

  19. 27-03-2024 | Parkinson's Disease | Online First

    Exosomal microRNAs in Parkinson’s disease: insights into biomarker potential and disease pathology

    Parkinson’s disease (PD) is a prevalent neurodegenerative condition primarily affecting the elderly population. Despite its high incidence in aged individuals, there are no reliable blood-based biomarkers for clinical diagnosis of PD and early …

  20. Open Access 28-02-2024 | Parkinson's Disease | OriginalPaper

    Anatomical correlates of apathy and impulsivity co-occurrence in early Parkinson’s disease

    Neuropsychiatric manifestations of Parkinson’s disease (PD) include a variety of hyperactive and hypoactive behaviors [ 1 ]. One of the most prevalent hyper-active behaviors in PD is impulse control disorders (ICDs), characterized by the inability …

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