Issue 1/2024
Content (24 Articles)
Blockage of VEGF function by bevacizumab alleviates early-stage cerebrovascular dysfunction and improves cognitive function in a mouse model of Alzheimer’s disease
Min Zhang, Zhan Zhang, Honghong Li, Yuting Xia, Mengdan Xing, Chuan Xiao, Wenbao Cai, Lulu Bu, Yi Li, Tae-Eun Park, Yamei Tang, Xiaojing Ye, Wei-Jye Lin
Nanotechnology for microglial targeting and inhibition of neuroinflammation underlying Alzheimer’s pathology
Hoda M. Gebril, Aravind Aryasomayajula, Mariana Reis Nogueira de Lima, Kathryn E. Uhrich, Prabhas V. Moghe
Increased cysteinyl-tRNA synthetase drives neuroinflammation in Alzheimer’s disease
Xiu-Hong Qi, Peng Chen, Yue-Ju Wang, Zhe-Ping Zhou, Xue-Chun Liu, Hui Fang, Chen-Wei Wang, Ji Liu, Rong-Yu Liu, Han-Kui Liu, Zhen-Xin Zhang, Jiang-Ning Zhou
Death-associated protein kinase 1 as a therapeutic target for Alzheimer's disease
Tao Zhang, Byeong Mo Kim, Tae Ho Lee
Correction: A novel transgenic mouse line with hippocampus-dominant and inducible expression of truncated human tau
Yang Gao, Yuying Wang, Huiyang Lei, Zhendong Xu, Shihong Li, Haitao Yu, Jiazhao Xie, Zhentao Zhang, Gongping Liu, Yao Zhang, Jie Zheng, Jian‑Zhi Wang
The therapeutic potential of probucol and probucol analogues in neurodegenerative diseases
Arazu Sharif, John Mamo, Virginie Lam, Hani Al-Salami, Armin Mooranian, Gerald F. Watts, Roger Clarnette, Giuseppe Luna, Ryu Takechi
The interaction between ageing and Alzheimer's disease: insights from the hallmarks of ageing
Yuqing Liu, Yejun Tan, Zheyu Zhang, Min Yi, Lemei Zhu, Weijun Peng
Life and disease status of patients with Parkinson’s disease during and after zero-COVID in China: an online survey
Pei Huang, Yu-Yan Tan, Biao Chen, Hui-Fang Shang, Li-Juan Wang, Chun-Feng Liu, Ling Chen, Ying Chang, Han Wang, Xue-Lian Wang, Xiao-Guang Lei, Li-Fen Yao, Yang Yu, Zheng Ye, Hai-Bo Chen, Sheng-Di Chen
Microstructural integrity of the locus coeruleus and its tracts reflect noradrenergic degeneration in Alzheimer’s disease and Parkinson’s disease
Chen-Pei Lin, Irene Frigerio, John G. J. M. Bol, Maud M. A. Bouwman, Alex J. Wesseling, Martin J. Dahl, Annemieke J. M. Rozemuller, Ysbrand D. van der Werf, Petra J. W. Pouwels, Wilma D. J. van de Berg, Laura E. Jonkman
Emerging role of senescent microglia in brain aging-related neurodegenerative diseases
Chan Rim, Min-Jung You, Minyeop Nahm, Min-Soo Kwon
α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes
Emmanouela Leandrou, Ioanna Chalatsa, Dimitrios Anagnostou, Christina Machalia, Maria Semitekolou, Vicky Filippa, Manousos Makridakis, Antonia Vlahou, Ema Anastasiadou, Kostas Vekrellis, Evangelia Emmanouilidou
Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside
Yuan-Yuan Ma, Xin Li, Jin-Tai Yu, Yan-Jiang Wang
LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
Noah Lubben, Julia K. Brynildsen, Connor M. Webb, Howard L. Li, Cheryl E. G. Leyns, Lakshmi Changolkar, Bin Zhang, Emily S. Meymand, Mia O’Reilly, Zach Madaj, Daniella DeWeerd, Matthew J. Fell, Virginia M. Y. Lee, Dani S. Bassett, Michael X. Henderson
Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
Alessandra Bigi, Giulia Fani, Valentina Bessi, Liliana Napolitano, Silvia Bagnoli, Assunta Ingannato, Lorenzo Neri, Roberta Cascella, Paolo Matteini, Sandro Sorbi, Benedetta Nacmias, Cristina Cecchi, Fabrizio Chiti
Biases in α-synuclein immuno-quantitation: a core problem for basic and ancillary studies of Parkinson’s disease and multiple system atrophy
Florent Laferrière, Ludivine Sabatier, Stéphane Claverol, Francesca De Giorgi, François Ichas
Dietary fasting and time-restricted eating in Huntington’s disease: therapeutic potential and underlying mechanisms
Russell G. Wells, Lee E. Neilson, Andrew W. McHill, Amie L. Hiller
Whole-brain dopamine transporter binding pattern predicts survival in multiple system atrophy
Yeon-koo Kang, Jung Hwan Shin, Hongyoon Choi, Han-Joon Kim, Gi Jeong Cheon, Beomseok Jeon
Pathophysiological subtypes of mild cognitive impairment due to Alzheimer’s disease identified by CSF proteomics
Daniela Moutinho, Vera M. Mendes, Alessandro Caula, Sara C. Madeira, Inês Baldeiras, Manuela Guerreiro, Sandra Cardoso, Johan Gobom, Henrik Zetterberg, Isabel Santana, Alexandre De Mendonça, Helena Aidos, Bruno Manadas
Stathmin 2 is a potential treatment target for TDP-43 proteinopathy in amyotrophic lateral sclerosis
Yunqing Liu, Dejun Yan, Lin Yang, Xian Chen, Chun Hu, Meilan Chen
CRISPR base editing-mediated correction of a tau mutation rescues cognitive decline in a mouse model of tauopathy
Min Sung Gee, Eunji Kwon, Myeong-Hoon Song, Seung Ho Jeon, Namkwon Kim, Jong Kil Lee, Taeyoung Koo
The role of the brain renin-angiotensin system in Parkinson´s disease
Jose Luis Labandeira-Garcia, Carmen M. Labandeira, Maria J. Guerra, Ana I. Rodriguez-Perez
Focusing on mitochondria in the brain: from biology to therapeutics
Nanshan Song, Shuyuan Mei, Xiangxu Wang, Gang Hu, Ming Lu
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer’s disease
Dongfang Jiang, Hongmei Liu, Tingting Li, Song Zhao, Keyan Yang, Fuwen Yao, Bo Zhou, Haiping Feng, Sijia Wang, Jiaqi Shen, Jinglan Tang, Yu-Xin Zhang, Yun Wang, Caixia Guo, Tie-Shan Tang