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4293 search results for:

Neutrophilia 

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  1. Open Access 01-12-2023 | Bronchial Asthma | OriginalPaper

    Exogenous IL-25 ameliorates airway neutrophilia via suppressing macrophage M1 polarization and the expression of IL-12 and IL-23 in asthma

    Asthma affects ~ 300 million people worldwide, and approximately 25,000 people died each year from asthma [ 1 ]. Severe asthma is a major challenge because of substantial mortality and the poor responsiveness to treatment including corticosteroids.

  2. Open Access 16-07-2022 | Melanoma | OriginalPaper

    Cytokine alterations during paraneoplastic neutrophilia and leukemoid reaction in patients with advanced melanoma

    Paraneoplastic leukemoid reaction (PLR) is defined as a tumor-induced leukocyte count of above 50 /nl and has been described in different tumor entities, including melanoma. Unawareness of this phenomenon may lead to unnecessary antibiotic …

  3. 01-03-2022 | Lymphopenia | OriginalPaper

    Prognostic impact of neutrophilia and lymphopenia on survival in anal cancer treated with definitive concurrent chemoradiotherapy: a retrospective multicenter study

    Anal cancer is a rare malignancy which accounts for approximately 0.1% of the cancer incidence in Korea [ 1 ]. Squamous cell carcinoma is the most common type of anal cancer, and generally develops after human papillomavirus (HPV) infection in …

  4. Open Access 01-12-2019 | Amyotrophic Lateral Sclerosis | OriginalPaper

    ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia

    Amyotrophic lateral sclerosis (ALS) is a fatal disease with inherited (familial) forms and sporadic subtypes arising spontaneously from gene-environment interactions. Mutations in superoxide dismutase ( SOD1 ) were the first to be associated with …

  5. 01-11-2021 | Neutrophilia | OriginalPaper

    Thrombocytosis and neutrophilia associated with oxygenator failure and protamine reaction after cardiopulmonary bypass: a case report and literature review

    Thrombocytosis has been feared as a source of thrombotic complications during the conduct of cardiopulmonary bypass (CPB) for patients undergoing cardiac procedures. We present a patient urgently requiring repair/replacement of three heart valves …

  6. 01-10-2019 | Chronic Neutrophilic Leukemia | Letter

    How to resolve a clinical and molecular puzzle: concomitant monoclonal gammopathy of undetermined significance (MGUS) with neutrophilia and clonal hematopoiesis of indeterminate potential (CHIP)

  7. 01-01-2019 | Letter

    Neutrophilia and the JAK2 V617F Mutation

  8. Open Access 01-12-2018 | OriginalPaper

    IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation

    Asthma exacerbation is episodic worsening of the asthma symptoms in patients with already on-going chronic inflammation. The frequency of exacerbations is associated with disease severity and may be a factor in aggravation of the basic respiratory …

  9. Open Access 01-12-2018 | OriginalPaper

    Development of membranoproliferative glomerulonephritis-like glomerulopathy in a patient with neutrophilia resulting from endogenous granulocyte-colony stimulating factor overproduction: a case report

    Recombinant human granulocyte-colony stimulating factor (G-CSF) induces a selective and transient increase in circulating neutrophils by stimulating bone marrow production. It is widely used in patients with neutropenia or to collect progenitor …

  10. 01-01-2018 | OriginalPaper

    Mechanisms of Sustained Neutrophilia in Patient WHIM-09, Cured of WHIM Syndrome by Chromothripsis

    WHIM-09 is the first patient described with WHIM syndrome, an autosomal dominant form of neutropenia related to bone marrow retention of neutrophils. Originally diagnosed incorrectly with autoimmune neutropenia, the patient underwent splenectomy …

  11. 01-02-2018 | OriginalPaper

    A score combining baseline neutrophilia and primary tumor SUVpeak measured from FDG PET is associated with outcome in locally advanced cervical cancer

    Although screening of cervical cancer has reduced its incidence in developed countries, it remains the fourth most common cause of cancer mortality worldwide in women [ 1 ]. And while cervical cancer has been reduced globally, especially in …

  12. 01-11-2016 | OriginalPaper

    Persistent neutrophilia is a marker for an increased risk of venous thrombosis

    In patients with cancer and myeloproliferative disorders, leukocytosis has been associated with an increased venous thromboembolic (VTE) risk. Our goal was to determine whether persistent neutrophilia (PN), not associated with known causes such as …

  13. 01-12-2015 | OriginalPaper

    EGCG induces G-CSF expression and neutrophilia in experimental sepsis

    A major green tea component, epigallocatechin-3-gallate (EGCG), has been proven protective against lethal sepsis in experimental setting, but its protective mechanisms remain incompletely understood. Here, we provide evidence to support EGCG’s …

  14. 01-01-2001 | OriginalPaper

    Neutrophilia and granulocyte colony-stimulating factor levels after cardiopulmonary bypass

    Purpose: The precise mechanism of neutrophilia after cardiac surgery is unknown. Granulocyte colony stimulating factor (G-CSF) can increase the number of leukocytes. The purpose of this study was to evaluate the relationship between serum G-CSF …

  15. 01-01-2001 | Abstract

    Perinatal neutrophil apoptosis: contribution to neonatal bacterial sepsis and maternal neutrophilia

  16. Open Access 01-12-2015 | OriginalPaper

    Effect of inhaled hydrosoluble curcumin on inflammatory markers in broncho-alveolar lavage fluid of horses with LPS-induced lung neutrophilia

    Horses commonly suffer from recurrent airway obstruction (RAO) or heaves, which is a severe, potentially debilitating, chronic inflammatory airway disease typically affecting middle-aged horses [ 1 ]. From a clinical point of view, the disease is …

  17. 01-06-2006 | OriginalPaper

    Acute blood neutrophilia induced by short-term compost dust exposure in previously unexposed healthy individuals

    Objectives: Systemic effects of organic dust inhalation have been described in farming environments. The purpose of this study was to examine whether a single exposure at a biowaste composting facility could also exert systemic effects in healthy …

  18. 01-06-2014 | Report

    Anaplastic large cell lymphoma with paraneoplastic neutrophilia: an association between IL-17 elevation and aggressive disease progression

    We report a case of anaplastic large cell lymphoma (ALCL) with involvement of bone marrow, exhibiting extreme leukocytosis leading to death due to multi-organ failure within 1 week after admission. The patient had a history of rheumatoid …

  19. Open Access 01-06-2012 | Abstract

    Relationship between plasma NGAL and serum creatinine is influenced by leucocytosis and neutrophilia in the critically ill

    NGAL appears to be a biomarker of acute kidney injury. It is produced by neutrophils and renal tubular cells. In healthy patients, plasma NGAL levels have been shown to vary with white blood cell concentrations. The predictive ability of NGAL to …

  20. Open Access 01-12-2010 | OriginalPaper

    Suppression of exercise-induced neutrophilia and lymphopenia in athletes by cystine/theanine intake: a randomized, double-blind, placebo-controlled trial

    Cystine, a dipeptide of the sulfur amino acid cysteine, is a precursor of glutathione (GSH) that is responsible for the antioxidant response in the body, and its supply is limiting in the synthesis of GSH[ 1 ]. On the other hand, theanine is an …

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