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Multiple Sclerosis in Childhood 

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  1. Open Access 09-05-2022 | Multiple Sclerosis | OriginalPaper

    Age-specific effects of childhood body mass index on multiple sclerosis risk

    Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the Central Nervous System (CNS), with both genetic and environmental risk factors [ 1 ]. Environmental factors including obesity, low serum vitamin D, infection with …

  2. 01-05-2001 | OriginalPaper

    Multiple Sclerosis In Childhood and Adolescence

    Clinical Features and Management

    The presentation of multiple sclerosis (MS) in childhood has traditionally been thought to be rare. However, more paediatric cases are now being reported, as a result of progress in diagnostic techniques with the use of sensitive imaging …

  3. 01-12-2008 | OriginalPaper

    Paediatric multiple sclerosis: The experience of the German Centre for Multiple Sclerosis in Childhood and Adolescence

    Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system and the most common disabling neurological disease in young adults. An estimated 5 % of MS patients already have first clinical symptoms before …

  4. Open Access 01-12-2011 | OriginalPaper

    Environmental factors in early childhood are associated with multiple sclerosis: a case-control study

    Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS), whose incidence has increased over recent decades in some parts of Europe [ 1 – 3 ] and features a specific geographical distribution with …

  5. 05-04-2024 | Multiple Sclerosis in Childhood | News | Article

    Early DMT reduces disability in pediatric MS

    Children with multiple sclerosis have a reduced risk of disability if treated early with high-efficacy disease-modifying therapies. 

  6. 14-03-2024 | Multiple Sclerosis in Childhood | News | Article

    Highly effective therapies should be first-line treatment for pediatric MS

    Moderately effective therapies are the main treatment for pediatric-onset multiple sclerosis, but first-line use of highly effective therapies provides greater reduction in relapse.

  7. Open Access 03-07-2022 | Multiple Sclerosis | OriginalPaper

    Abuse and revictimization in adulthood in multiple sclerosis: a cross-sectional study during pregnancy

    People with multiple sclerosis (MS) are more often exposed to abuse and neglect in childhood than the general population [ 1 – 4 ]. Mistreatment in childhood is a strong predictor of abuse later in life, known as revictimization [ 5 ]. It is not …

  8. Open Access 01-12-2024 | Multiple Sclerosis | OriginalPaper

    Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO)

    Multiple Sclerosis (MS) is an inflammatory, degenerative disease of the central nervous system (CNS) [ 1 , 2 ] and the most common inflammatory neurological disease causing disability in early adulthood [ 3 ]. MS is characterized by relapses …

  9. 04-10-2023 | Multiple Sclerosis | ReviewPaper

    Pediatric Multiple Sclerosis: Changing the Trajectory of Progression

    Pediatric MS is characterized by highly active disease and high disease burden. Prompt recognition is essential, as early intervention with disease-modifying therapies is needed to achieve optimal outcomes in this population.

  10. 01-04-2024 | Events

    SPR 2024

  11. 05-08-2023 | Optic Neuritis | Review

    Differentiating and treating optic neuritis

    An overview of the clinical manifestations and treatment of demyelinating and autoimmune optic neuritis, which is the most common cause of subacute optic neuropathy in young adults.

  12. Open Access 01-12-2024 | Epilepsy | OriginalPaper

    Profile of adult -onset epilepsy in Zagazig university hospitals

    Epilepsy is one of the most common neurologic diseases in the world that affects approximately two million people in the United States and more than 50 million people worldwide, with 16–51 cases of new-onset epilepsy per 100,000 people every year …

  13. Open Access 01-12-2024 | Acute Lymphoblastic Leukemia | OriginalPaper

    Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis

    B-cell acute lymphoblastic leukemia (B-ALL) is a prevalent subtype of leukemia characterized by its highly malignant nature, primarily originating from the clonal expansion and abnormal proliferation of B lymphocytes within the hematopoietic …

  14. 14-05-2024 | Osteomyelitis | Online First

    The many faces of sickle cell disease in children: complications in the appendicular skeleton

    Sickle cell disease (SCD) is a hereditary red cell disorder with clinical manifestations secondary to sickling or crescent-shaped distortion of the red blood cells. Musculoskeletal complications of SCD are often the main causes for acute and …

  15. Open Access 24-04-2024 | Shingles | Online First

    Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK

    Primary infection by the varicella-zoster virus leads to childhood varicella (chickenpox) in the majority of the population. The virus remains dormant in the dorsal root ganglia, and can be reactivated later in life, causing herpes zoster (HZ) [ 1 …

  16. 08-05-2024 | Perampanel | Online First

    Efficacy and safety of adjunctive perampanel treatment in pediatric patients with epilepsy aged 4–12 years: a real-world study

    Perampanel (PER) is a novel third-generation antiseizure medication (ASM) that is a noncompetitive antagonist of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor on postsynaptic neurons [ 1 ]. The AMPA receptor is the …

  17. Open Access 29-12-2023 | Multiple Sclerosis | ReviewPaper

    Neuropsychological performances, quality of life, and psychological issues in pediatric onset multiple sclerosis: a narrative review

    Multiple sclerosis (MS) is primarily a disease diagnosed in young and middle-aged adults. Although MS is a rare condition in pediatric age, an increasing rate of patients is diagnosed under the age of 18. The disabling nature of the disease cannot …

  18. 27-04-2024 | Abstract

    Student Summer Research Awards – SSRA Abstracts of the SSRA September 2023 meeting, UCD School of Medicine

  19. 29-04-2024 | Lymphoma | Online First

    What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?

    The classification of tumors is essential in the diagnosis and clinical management of patients with malignant neoplasms. The World Health Organization (WHO) provides a globally applicable classification scheme of neoplasms and it was updated …

  20. 20-03-2024 | Events

    Abstracts

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