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10164 search results for:

Mixed Connective Tissue Disease 

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  1. 21-03-2024 | Mixed Connective Tissue Disease | OriginalPaper

    Naifold capillaroscopy in mixed connective tissue disease patients

    Mixed connective tissue disease (MCTD) is a chronic autoimmune systemic connective tissue disease. It is characterized by overlapping features of various systemic connective tissue diseases, including systemic lupus erythematosus (SLE), systemic …

  2. Open Access 01-12-2024 | Pulmonary Hypertension | OriginalPaper

    Fractional exhaled nitric oxide in idiopathic pulmonary arterial hypertension and mixed connective tissue disease complicating pulmonary hypertension

    PH is a rare and progressive disease that can have several potential etiologies and is associated with respiratory and cardiovascular diseases. It is characterized by elevated lung vascular resistance, ultimately leading to premature death [ 1 ].

  3. 07-04-2024 | Mixed Connective Tissue Disease | Online First

    Headache and cerebral venous sinus thrombosis as a first presentation of mixed connective tissue disease: a rare case and literature review

  4. Open Access 01-12-2024 | Mixed Connective Tissue Disease | OriginalPaper

    Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

    Overlap autoimmune syndromes (OAS) are rare rheumatic diseases in children at the intersection of several systemic autoimmune diseases [ 1 ]. Mixed connective tissue disease (MCTD) is a distinct subset of overlap autoimmune syndromes characterised …

  5. Open Access 01-12-2023 | Mixed Connective Tissue Disease | OriginalPaper

    Association of red cell distribution width with pulmonary arterial hypertension in patients with mixed connective tissue disease

    Mixed connective tissue disease (MCTD) is one of the most complicated autoimmune diseases and involves various overlapping symptoms [ 1 ]. It is characterized by diverse clinical manifestations of systemic sclerosis (SSc), systemic lupus …

  6. 07-08-2023 | Mixed Connective Tissue Disease | Online First

    Extramural hematoma after esophageal stricture dilatation in mixed connective tissue disease

  7. 01-12-2021 | Scleroderma

    Association study between immune-related miRNAs and mixed connective tissue disease

    Autoimmunity, an abnormal response of the body to its own tissue antigens, is manifested in many ways that are categorized into various types of diseases depending on the tissue and antigen targeted. Mixed connective tissue disease (MCTD) is a …

  8. 12-03-2023 | Systemic Lupus Erythematosus | OriginalPaper

    Pediatric mixed connective tissue disease versus other overlap syndromes: a retrospective multicenter cohort study

    Pediatric mixed connective tissue disease (MCTD) is a subgroup of overlap syndromes. We aimed to compare the characteristics and outcomes in children with MCTD and other overlap syndromes. All MCTD patients met either Kasukawa or Alarcon-Segovia …

  9. Open Access 18-03-2023 | Echocardiography | OriginalPaper

    Cardiac dysfunction in mixed connective tissue disease: a nationwide observational study

    We aimed to identify cardiac function in patients with established mixed connective tissue disease (MCTD). This was a cross-sectional case–control study of well-characterised MCTD patients who had previously been included in a nationwide cohort.

  10. 01-02-2021 | Edema

    99mTc-HSA-DTPA Scintigraphy of Protein-Losing Gastroenteropathy Associated with Mixed Connective Tissue Disease Before and After Immunosuppressive Therapy

    We present a female in her sixties with mixed connective tissue disease who underwent 99mTc-human serum albumin diethylenetriaminepentaacetic acid (99mTc-HSA-DTPA) scintigraphy to clarify the cause of generalized edema. Scintigraphy findings …

  11. 01-06-2020 | Vasculitis | OriginalPaper

    Congestive hepatopathy and acute pancreatitis as severe complications of mixed connective tissue disease

    Mixed connective tissue disease (MCTD) causes multiple organ dysfunctions, such as joint swelling, pulmonary fibrosis and hypertension, and serositis, but hepatopancreatic complications are rare. Here, we report a case of young man who exhibited …

  12. Open Access 29-07-2022 | Systemic Lupus Erythematosus | OriginalPaper

    The enigma of mixed connective tissue disease—challenges in routine care

    Mixed connective tissue disease (MCTD) is a systemic, immune-mediated disorder exhibiting a broad spectrum of disease manifestations including symptoms of systemic sclerosis (SSc), systemic lupus erythematosus (SLE), primary myositis (PM) or …

  13. Open Access 01-05-2020 | Mixed Connective Tissue Disease | ReviewPaper

    Mixed connective tissue disease”: a condition in search of an identity

    Mixed connective tissue disease was first described as a new autoimmune rheumatic disease in 1972 based on the claim of a distinct clinical picture associated with anti-RNP antibody positivity. Subsequently, this new entity has divided opinions in …

  14. 25-08-2021 | Myasthenia Gravis | ReviewPaper

    Mixed connective tissue disease after thymectomy in refractory myasthenia gravis

    Connective tissue diseases, including systemic lupus erythematosus (SLE) and systemic sclerosis are classic models of autoimmunity; diseases with large-scale loss of tolerance and subsequent development of pathogenic autoreactive lymphocytes and …

  15. Open Access 01-01-2022 | Systemic Lupus Erythematosus | OriginalPaper

    Relationship between type of skin lesions and nailfold capillaroscopy pattern in mixed connective tissue disease

    Mixed connective tissue disease (MCTD) is a rare systemic autoimmune disease with an overlapping feature of at least two connective tissue diseases (CTDs), including systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis (PM) …

  16. 01-05-2019 | Systemic Lupus Erythematosus | OriginalPaper

    Imaging findings of mixed connective tissue disease in children and adolescents: a case series

    Mixed connective tissue disease (MCTD) is a rare disease in children and adolescents which overlaps features of juvenile idiopathic arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, and systemic sclerosis. We have provided an …

  17. 01-05-2021 | Human Immunodeficiency Virus | OriginalPaper

    Collapsing glomerulopathy in a patient with mixed connective tissue disease

    Collapsing glomerulopathy (CG) is a distinct podocytopathy characterized by the global or segmental collapse of glomerular capillary tuft with overlying podocyte hypertrophy and hyperplasia. CG has been associated with numerous etiologies …

  18. 01-12-2020 | Ultrasound

    Salivary gland ultrasound in the diagnostic workup of juvenile Sjögren’s syndrome and mixed connective tissue disease

    Sjögren’s Syndrome (SS) has originally been described as a chronic autoimmune disease affecting the lacrimal and salivary glands. Primary SS (pSS) is nowadays understood to be a systemic autoimmune disease involving the lungs, kidneys, skin and …

  19. 01-09-2019 | Systemic Lupus Erythematosus | ReviewPaper

    Myelopathy associated with mixed connective tissue disease: clinical manifestation, diagnosis, treatment, and prognosis

    Mixed connective tissue disease (MCTD) is a chronic autoimmune disease, which has a broad range of clinical manifestations shared by systemic lupus erythematosus, systemic sclerosis, polymyositis/dermatomyositis, and rheumatoid arthritis. MCTD is …

  20. 01-07-2018 | ReviewPaper

    The impact of anti-U1-RNP positivity: systemic lupus erythematosus versus mixed connective tissue disease

    Anti-U1-RNP positivity remains mandatory for the mixed connective tissue disease (MCTD) diagnosis, reason for which anti-U1-RNP occurrence in patients with lupus clinical features might determine diagnostic issues. Thus, the prevalence of 25–30% …

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