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664 search results for:

Meningococcus 

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  1. 21-02-2023 | Human Papillomavirus | ReviewPaper

    Accounting for Adverse Events Following Immunization in Economic Evaluation: Systematic Review of Economic Evaluations of Pediatric Vaccines Against Pneumococcus, Rotavirus, Human Papillomavirus, Meningococcus and Measles-Mumps-Rubella-Varicella

    Vaccines receive authorization for marketing only if potential adverse events following immunization (AEFI) are outweighed by the protective benefits they offer and if a risk management strategy is in place to identify any remaining uncertainties …

  2. Open Access 01-12-2019 | Meningococcus | OriginalPaper

    Safety and tolerability of Meningococcus B vaccine in patients with chronical medical conditions (CMC)

    Invasive meningococcal disease is a serious global health threat in the world and has an high mortality and morbidity rate; about one in ten survivors will have major physical or neurological disabilities and Meningitis B accounts for about 80% of …

  3. 01-09-2017 | ReviewPaper

    Serogroup B Meningococcus Outbreaks, Prevalence, and the Case for Standard Vaccination

    Meningococcal infections continue to represent one of the most feared infectious diseases across age ranges, causing meningococcemia, meningococcal meningitis, and Waterhouse-Friderichsen hemorrhagic adrenalitis. The National Notifiable Diseases …

  4. Open Access 01-12-2015 | Abstract

    Meningococcus B

  5. 01-07-2016 | OriginalPaper

    Serological Analysis of Immunogenic Properties of Recombinant Meningococcus IgA1 Protease-Based Proteins

    Using the genome sequence of IgA1 protease of N. meningitidis of serogroup B, four recombinant proteins of different structure and molecular weight were constructed. These proteins were equal in inducing the formation of specific antibodies to …

  6. 01-06-2001 | OriginalPaper

    Myocardial injury in meningococcus-induced purpura fulminans in children

    Objectives: To assess the incidence of myocardial ischemia in meningococcus-induced purpura fulminans in pediatric patients, to compare troponin I (cTnI) levels with changes in electrocardiogram (ECG) and to evaluate whether cTnI is related to …

  7. Open Access 01-12-2024 | Meningococcus | OriginalPaper

    Diverse proinflammatory response in pharyngeal epithelial cells upon interaction with Neisseria meningitidis carriage and invasive isolates

    Neisseria meningitidis (the meningococcus) can cause invasive meningococcal disease (IMD) with high morbidity and mortality through epidemic or sporadic meningitis and/or septicaemia [ 1 ]. IMD results from a multifactorial process involving …

  8. 01-10-2018 | OriginalPaper

    Peculiarities of the Formation of Antimeningococcus Immunity in Mice Immunized with Fragments of N. meningitidis IgA1 Protease

    We studied immunogenicity of two recombinant proteins FR.9 and FR.11-3 created on the basis of fragments of the primary structure of N. meningitidis IgA1 protease with different molecular weights containing different sets of T and B epitopes. The …

  9. 01-04-2024 | Systemic Lupus Erythematosus | News

    Multiple drugs

    Lack of efficacy and myelosuppression
  10. 26-10-2023 | Streptococci | OriginalPaper

    Increased rates of invasive bacterial disease in late 2022

    Infection is still the leading cause of child mortality globally, particularly in the younger age group [ 1 ] and is associated with higher rates of intensive care admissions, and a higher degree of long-standing disability and death in older …

  11. 28-10-2023 | Splenectomy | Online First

    Epidermoid Splenic Cyst in Children Treated by Laparoscopic Partial Splenectomy: Three Case Reports and Literature Review

    The authors report three cases of epidermoid splenic cysts successfully treated by laparoscopic partial splenectomy: a 7-year-old girl, with a 4.5 cm lower pole squamous cell cyst; a 13-year-old boy, type 1 diabetic on insulin therapy, with a 7 cm …

  12. Open Access 01-12-2020 | OriginalPaper

    Transmissibility and pathogenicity of the emerging meningococcal serogroup W sequence type-11 complex South American strain: a mathematical modeling study

    The meningococcus ( Neisseria meningitidis ) is a bacterium that frequently colonizes the human nasopharynx, particularly that of adolescents and young adults [ 1 ]. Although colonization is typically asymptomatic and harmless to the host, the …

  13. Open Access 15-05-2024 | Chronic Inflammatory Bowel Disease | Online First

    Conception, pregnancy and inflammatory bowel disease—Current concepts for the practising clinician

    The peak incidence of inflammatory bowel disease (IBD) coincides with a woman’s prime reproductive years. The management of IBD during pregnancy can be challenging for healthcare professionals, underpinning the need for a multi-disciplinary …

  14. 11-05-2024 | Online First

    Autonomic neuropathy improving after intravenous immunoglobulin therapy

  15. Open Access 01-12-2023 | Hereditary Angioedema | Abstract

    13th C1-inhibitor deficiency and angioedema workshop—2023

    Edited by: Róbert Hohol; Lectored by: Henriette Farkas, Lilian Varga; Cover artwork: Gergely Hosszú
  16. Open Access 27-04-2024 | Meningitis | Online First

    PCR-positive meningococcal CSF infection without pleocytosis but high IL-6 and IL-8

    Bacterial meningitis still poses a severe health threat worldwide, with incidence rates ranging from 0.9 to 80 per 100,000 persons and a mortality rate of up to 54% in low-income countries [ 1 ]. Neisseria ( N. ) meningitidis is the second most …

  17. Open Access 01-12-2024 | Splenectomy | OriginalPaper

    Splenic torsion mistaken for an ovarian cyst: a case report 

    Wandering spleen (or ectopic spleen) refers to a hyper-mobile spleen resulting in its displacement from the normal anatomical position to usually in the lower abdominal or pelvic cavity. In most rural settings, ultrasound is often the first …

  18. 23-10-2023 | Meningitis | ReviewPaper

    Shorter versus longer duration of antibiotic treatment in children with bacterial meningitis: a systematic review and meta-analysis

    The optimal duration of antibiotic treatment for the most common bacterial meningitis etiologies in the pediatric population, namely Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis, is not well-established in the …

  19. Open Access 01-12-2022 | Meningioma | OriginalPaper

    Development of a multicellular in vitro model of the meningeal blood-CSF barrier to study Neisseria meningitidis infection

    Bacterial meningitis is a devastating disease defined by meningeal inflammation in response to bacterial infection [ 1 , 2 ]. Despite vaccination efforts, the human-specific, Gram-negative bacterium Neisseria meningitidis (Nm, meningococcus) …

  20. Open Access 01-12-2019 | Vaccination | OriginalPaper

    The effect of a single 4CMenB vaccine booster in young people more than ten years after infant immunisation: protocol of an exploratory immunogenicity study

    Despite the existence of effective antibiotics and recent advances in vaccinology, meningococcal disease remains firmly in the public eye. Of the main Neisseria meningitidis capsular groups which cause disease in humans, group B meningococcus

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