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Kaposi's Sarcoma-Associated Herpesvirus 

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  1. 01-05-2024 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Analysis of the interaction between the ORF42 and ORF55 proteins encoded by Kaposi’s sarcoma-associated herpesvirus

    Kaposi’s sarcoma-associated herpesvirus (KSHV) causes Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman disease. The tegument is a structure that is unique to herpesviruses that includes host and viral proteins, including the …

  2. Open Access 29-03-2024 | Hemophagocytic Lymphohistiocytosis | Online First

    Differential diagnosis between kaposi sarcoma-associated herpesvirus cytokine syndrome and hemophagocytic lymphohistiocytosis

  3. Open Access 01-12-2024 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Nelfinavir inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly

    Kaposi sarcoma is a tumor associated with Kaposi’s sarcoma-associated herpesvirus (KSHV also known as HHV-8). Transmission is believed to be salivary in most instances [ 1 – 6 ]. Agents that inhibit KSHV lytic replication have not been shown to be …

  4. Open Access 01-12-2023 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Comparison of Epstein–Barr virus and Kaposi’s sarcoma-associated herpesvirus viral load in peripheral blood mononuclear cells and oral fluids of HIV-negative individuals aged 3–89 years from Uganda

    We previously found that age, sex and malaria were associated with KSHV in individuals from Uganda. In this study, we have evaluated these same factors in relation to EBV in the same specimens. Overall, 74% (oral fluids) and 46% (PBMCs) had …

  5. Open Access 01-12-2023 | Hepatitis B | OriginalPaper

    Seroprevalence and risk factors for Kaposi’s Sarcoma associated herpesvirus among men who have sex with men in Shanghai, China

    Kaposi’s sarcoma associated herpesvirus (KSHV), also termed human herpesvirus type 8 (HHV-8), has been considered as the etiologic agent for Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), multicentric Castleman’s disease (MCD) and …

  6. Open Access 01-04-2020 | Herpes Virus | ReviewPaper

    Epigenetic control in Kaposi sarcoma-associated herpesvirus infection and associated disease

    Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of several malignancies of endothelial and B-cell origin. The fact that latently infected tumor cells in these malignancies do not express classical viral oncogenes suggests that …

  7. Open Access 01-12-2020 | Malaria | OriginalPaper

    Malaria during pregnancy and transplacental transfer of Kaposi sarcoma-associated herpesvirus (KSHV) antibodies: a cohort study of Kenyan mother and child pairs

    Kaposi sarcoma-associated herpesvirus (KSHV) is the etiological agent for Kaposi sarcoma (KS), one of the ten most common cancers in Kenya [ 1 ]. In sub-Saharan Africa where KSHV is endemic, primary infection predominately occurs in young children.

  8. 01-02-2023 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Parthenolide inhibits proliferation of cells infected with Kaposi’s sarcoma-associated herpesvirus by suppression of the NF-κB signaling pathway

    The disease caused by Kaposi’s sarcoma-associated herpesvirus (KSHV) is one of the major causes of death of individuals with acquired immunodeficiency syndrome (AIDS). Development of anti-KSHV drugs is thus crucial. In this study, we investigated …

  9. Open Access 01-12-2021 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Kaposi’s sarcoma-associated herpesvirus infection promotes proliferation of SH-SY5Y cells by the Notch signaling pathway

    Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the human oncogenic virus of Kaposi’s sarcoma (KS). KSHV infection is linked to other lymphoproliferative malignancies, including primary effusion …

  10. Open Access 01-12-2022 | Herpes Virus | OriginalPaper

    Prevalence and correlates of Kaposi’s sarcoma-associated herpesvirus and herpes simplex virus type 2 infections among adults: evidence from the NHANES III data

    Kaposi’s sarcoma-associated herpes virus (KSHV) also referred as human herpesvirus-8 (HHV-8), is the etiologic agent for the occurrence of Kaposi's sarcoma (KS), Primary effusion lymphoma (PEL) and Multicentric Castleman's disease (MCD) [ 1 – 3 ].

  11. Open Access 01-12-2020 | Infliximab | OriginalPaper

    Human herpesvirus 8-associated colonic Kaposi’s sarcoma during vedolizumab treatment in ulcerative colitis: a case report and review of the literature

    Kaposi’s sarcoma (KS) is a rare vascular tumor associated with human herpesvirus (HHV)-8 infection [ 1 ]. KS lesions typically involve the skin or mucosal surfaces and are characterized by multiple red-purple or brown-black macules, papules, and …

  12. Open Access 01-12-2021 | Kaposi's Sarcoma-Associated Herpesvirus | OriginalPaper

    Targeting the Kaposi’s sarcoma-associated herpesvirus genome with the CRISPR-Cas9 platform in latently infected cells

    The technology involving 'clustered regulatory interspaced short palindromic repeat' (CRISPR) is recognized as a revolution in the field of molecular biology research, gene editing, and gene therapy. In nature, the CRISPR-Cas9 system functions in …

  13. Open Access 01-12-2017 | Report

    Seroprevalence of antibodies against Kaposi's sarcoma-associated herpesvirus among HIV-negative people in China

    Kaposi’s sarcoma-associated herpesvirus (KSHV), also referred to as human herpesvirus-8 (HHV-8), is the etiologic agent of KS, primary effusion lymphomas and multicentric Castleman’s disease (IARC 2012 Vol 100B). Contrary to other herpesviruses …

  14. Open Access 01-12-2016 | OriginalPaper

    Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi’s sarcomaassociated herpesvirus

    Kaposi’s sarcomaassociated herpesvirus (KSHV), or human herpesvirus 8 (HHV-8), is a member of gamma herpesvirus family, first isolated from Kaposi sarcoma lesions in AIDS patients [ 1 , 2 ]. KSHV has since also been detected in certain …

  15. Open Access 01-06-2009 | Abstract

    AKT/TSC/mTOR activation by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor: novel therapeutic targets for the treatment of Kaposi's sarcoma

  16. Open Access 01-10-2010 | Abstract

    Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman’s disease, and primary effusion lymphoma

    Kaposi sarcoma-associated herpesvirus (KSHV), also called human herpesvirus-8 (HHV-8), is the causative agent of all forms of Kaposi sarcoma (KS), as well as two rare B-cell HIV lymphoproliferative disorders, primary effusion lymphoma (PEL) and …

  17. Open Access 01-12-2011 | OriginalPaper

    Parasite infection is associated with Kaposi's sarcoma associated herpesvirus (KSHV) in Ugandan women

    Infection with KSHV is the underlying cause of Kaposi's sarcoma (KS), although it may not be sufficient [ 1 ]. Immune suppression, such as that caused by human immunodeficiency virus (HIV), significantly increases the risk of KS among KSHV infected …

  18. Open Access 01-06-2009 | Abstract

    Cellular gene regulation by K13/VFLIP of Kaposi's sarcoma-associated herpesvirus

  19. Open Access 01-10-2010 | Abstract

    Kaposi’s sarcoma-associated herpesvirus (KSHV) serum DNA not associated with subsequent non-Hodgkin’s lymphoma (NHL) risk

    Non-Hodgkin’s lymphoma (NHL) is a diverse group of cancers, elevated in HIV-infected individuals. Kaposi’s sarcoma-associated herpes virus (KSHV) is found in a subset of NHL tumors, and could therefore be a cause of NHL. However, antibody testing …

  20. Open Access 01-12-2012 | Abstract

    A regulatory circuit between Kaposi sarcoma-associated herpesvirus and host innate immune system

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