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1765 search results for:

Juvenile Dermatomyositis 

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  1. 28-03-2024 | Juvenile Dermatomyositis | OriginalPaper

    Unveiling Cardiac Involvement in Juvenile Dermatomyositis Through Speckle-Tracking Echocardiography

    Early detection of cardiac involvement in Juvenile Dermatomyositis (JDM) is difficult due to the absence of clinical signs and symptoms, with systolic dysfunction often emerging in late stages and associated with a poor prognosis. This study aimed …

  2. Open Access 01-12-2024 | Juvenile Dermatomyositis | OriginalPaper

    Local injection of infliximab into calcinosis lesions in patients with juvenile dermatomyositis (JDM): a clinical trial

    Juvenile dermatomyositis (JDM) is a rare autoimmune disease of childhood and the most common type of juvenile idiopathic inflammatory myopathy mainly affecting the skin and muscles [ 1 ]. JDM has an annual incidence of 2–4 cases per 1 million …

  3. 07-12-2023 | Juvenile Dermatomyositis | ReviewPaper

    Calcinosis in Juvenile Dermatomyositis—Epidemiology, Pathogenesis, Clinical Features, and Treatment: A Systematic Review

    Juvenile dermatomyositis (JDM) is a chronic, rare, multisystem autoimmune disease characterized by an immune response against skeletal muscle and other tissues, such as the skin, gastrointestinal tract, cardiac, and pulmonary systems [ 1 , 2 ].

  4. 16-08-2023 | Juvenile Dermatomyositis | ReviewPaper

    Biologic drugs in the treatment of juvenile dermatomyositis: a literature review

    There is no clear consensus in the literature regarding the choice of biologic therapies and efficacy in juvenile dermatomyositis (JDM). In this review, we aimed to examine previous studies regarding biologic drug use in JDM patients. We screened …

  5. Open Access 01-12-2023 | Juvenile Dermatomyositis | Letter

    Lung infection or inflammation-a puzzling case of MDA-5 associated juvenile dermatomyositis

    Juvenile dermatomyositis (JDM) is a rare form of inflammatory myopathy that primarily affects children under 18 years of age. Its diagnosis relies on identifying specific clinical features such as proximal muscle weakness, skin rash, elevated …

  6. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Clinical nomogram assisting in discrimination of juvenile dermatomyositis-associated interstitial lung disease

    Juvenile dermatomyositis (JDM) is an uncommon immune-mediated systemic autoimmune vascular disorder characterized by symmetrical proximal muscle weakness, elevated serum muscle enzymes, and distinctive cutaneous manifestations such as Gottron …

  7. Open Access 01-12-2023 | Tocilizumab | OriginalPaper

    Treatment escalation patterns to start biologics in refractory moderate juvenile dermatomyositis among members of the Childhood Arthritis and Rheumatology Research Alliance

    The idiopathic inflammatory myopathies (IIM) are a heterogenous group of autoimmune connective tissue diseases characterized by chronic skeletal muscle inflammation. There are different clinical myositis subtypes. Juvenile dermatomyositis (JDM) …

  8. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Juvenile dermatomyositis: association between nail fold capillary end row loop– area under the curve– and disease damage indicators

    Juvenile Dermatomyositis (JDM) is a systemic pediatric autoimmune disease characterized by skin and muscle inflammation [ 1 ]. Although it is the most common pediatric inflammatory myopathy, with an incidence rate of approximately 3.2 cases per …

  9. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Janus kinase inhibitor, tofacitinib, in refractory juvenile dermatomyositis: a retrospective multi-central study in China

    Juvenile dermatomyositis (JDM) is a chronic autoimmune disease. It has been confirmed as the most prevalent subgroup of juvenile idiopathic inflammatory myopathies (IIM) [ 1 ]. JDM primarily affects skin and muscle and other organs can be affected.

  10. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Nailfold capillary density in 140 untreated children with juvenile dermatomyositis: an indicator of disease activity

    Although Juvenile dermatomyositis (JDM) is the most common of the pediatric inflammatory myopathies, it is a rare disease. The annual USA average incidence is 3.2 cases/million children/year white, non-Hispanic, 3.3/million African Americans, and …

  11. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Juvenile Dermatomyositis in Afro-Caribbean children: a cohort study in the French West Indies

    In populations of African descent, the clinical presentation and epidemiology of auto-immune and auto-inflammatory diseases is quite particular [ 1 , 2 ]. The epidemiology and clinical features of Juvenile Dermatomyositis (JDM) in populations of …

  12. Bone within bone in juvenile dermatomyositis

    Twenty-eight-year-old woman with juvenile dermatomyositis (JDM) since 7 years old who was taking immunosuppressive therapy (azathioprine 100 mg/day and mycophenolate mofetil 3 g/day) presented as an asymptomatic patient for a rheumatology …

  13. Open Access 01-12-2023 | Juvenile Dermatomyositis | ReviewPaper

    Macrophage activation syndrome in juvenile dermatomyositis: a case report and a comprehensive review of the literature

    Juvenile dermatomyositis (JDM) is a subtype of idiopathic inflammatory myopathies (IIM), a group of diseases characterized by muscle inflammation and weakness. JDM presents with heliotrope rash and/or Gottron’s papules [ 1 ]. Hemophagocytic …

  14. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Rapid and sustained response to JAK inhibition in a child with severe MDA5 + juvenile dermatomyositis

    Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood [ 1 ]. This systemic autoimmune disease is associated with typical changes in the skin, vasculopathy, and muscle weakness that is usually trunk …

  15. 05-07-2023 | Juvenile Dermatomyositis | Online First

    Long-standing and poorly controlled disease in juvenile dermatomyositis is associated with calcinosis: a real-world experience from a low-middle income country

    To study the prevalence and predictors of calcinosis in Juvenile Dermatomyositis (JDM). Medical records over 20 years at a tertiary care rheumatology center in Northern India were reviewed to identify patients with JDM and clinical details were …

  16. Open Access 01-12-2022 | Ultrasound | OriginalPaper

    Nodular Regenerative Hyperplasia of the liver in Juvenile Dermatomyositis

    Nodular regenerative hyperplasia (NRH) is a rare vascular disorder of the liver associated with immunological or inflammatory systemic disorders and drug-related injuries that may progress to non-cirrhotic portal hypertension [ 1 ], with …

  17. Open Access 01-12-2022 | Retinoblastoma | OriginalPaper

    Chemotherapy induced juvenile dermatomyositis: a novel presentation- a case report

    DM is a type of idiopathic inflammatory myopathy that manifests as gradual, symmetrical weakening in the proximal muscles as well as characteristic cutaneous changes [ 1 ]. It could involve different organs like the heart, stomach, intestines …

  18. 31-08-2023 | Atopic Dermatitis | Online First

    Anti-TIF-1γ Positive Juvenile Dermatomyositis Diagnosed with Atopic Dermatitis

  19. Open Access 01-12-2023 | Juvenile Dermatomyositis | OriginalPaper

    Currently recommended skin scores correlate highly in the assessment of patients with Juvenile Dermatomyositis (JDM)

    Although childhood rheumatic diseases are currently not curable, they are treatable. The development of standardized outcome measures has been pivotal in assessing and following response to treatment.

  20. Open Access 01-12-2022 | Arthritis | OriginalPaper

    Baseline characteristics of children with juvenile dermatomyositis enrolled in the first year of the new Childhood Arthritis and Rheumatology Research Alliance registry

    Juvenile dermatomyositis (JDM) is the most common inflammatory myopathy in children but it is nonetheless rare, with an estimated annual incidence of 2–4 in 1 million children in the United States [ 1 ]. JDM is a systemic autoimmune disease …

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