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3121 search results for:

Hyperprolactinemia 

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  1. Open Access 09-01-2024 | Hyperprolactinemia | OriginalPaper

    Are prolactin levels efficient in predicting a pituitary lesion in patients with hyperprolactinemia?

    Hyperprolactinemia (hyperPRL) is the most common pituitary disorder, with a prevalence ranging from 0.4% in an unselected normal adult population to 9-17% in women with reproductive disorders [ 1 , 2 ] and it is due to an increase in circulating …

  2. Open Access 01-12-2023 | Hyperprolactinemia | Letter

    Late-onset symptomatic hyperprolactinemia in 6-pyruvoyl-tetrahydropterin synthase deficiency

    Hyperphenylalaninemia (HPA) is caused by variants either within the gene for the hepatic enzyme phenylalanine hydroxylase (PAH) or in genes involved in the production or recycling of tetrahydrobiopterin (BH 4 ). According to the International …

  3. Open Access 01-12-2023 | Antipsychotics | OriginalPaper

    The effect of antipsychotic medication and the associated hyperprolactinemia as a risk factor for periodontal diseases in schizophrenic patients: a cohort retrospective study

    Periodontal disease is a microbial, chronic inflammatory disease that occurs in susceptible individuals. Primarily, it is due to the interaction of two forces: microbial imbalance and the host immune response [ 1 , 2 ]. It is clinically identified …

  4. 01-03-2023 | Acromegaly | OriginalPaper

    Frequency of hyperostosis frontalis interna in patients with active acromegaly: is there a possible role of GH excess or hyperprolactinemia in its etiopathogenesis?

    Acromegaly is a chronic and progressive disease resulting in chronically elevated GH and insulin-like growth factor-I (IGF-I) levels. Excess GH and IGF-I disrupt bone microarchitecture in patients with acromegaly, thereby impairing quality of life …

  5. 01-05-2022 | Hyperprolactinemia

    Beneficial effects of irisin in experimental paroxetine-induced hyperprolactinemia

    Selective serotonin reuptake inhibitors (SSRIs) are widely used as first-line agents in the treatment of many mood and anxiety disorders [ 1 ]. Despite this widespread use, they can cause adverse effects especially on reproductive functions, and …

  6. 01-06-2021 | Pituitary Adenoma | OriginalPaper

    True hyperprolactinemia in men without visible pituitary adenoma

    Prolactinomas, benign prolactin (PRL)-secreting tumors, are the most common functional pituitary adenomas, accounting for 60% of secreting pituitary tumors. Prolactinomas are subdivided into microprolactinomas (<10 mm) and macroprolactinomas …

  7. 01-05-2021 | Pituitary Adenoma

    Hyperprolactinemia and association with prolactinoma in transwomen receiving gender affirming hormone treatment

    Approximately one-in-five transgender women will develop hyperprolactinemia following commencement of feminising hormone treatment [ 1 ]. Prolactin levels typically normalise with estradiol dose reduction, although a subset will develop persistent …

  8. 01-05-2021 | Hyperprolactinemia | ReviewPaper

    Is Adjunct Aripiprazole Effective in Treating Hyperprolactinemia Induced by Psychotropic Medication? A Narrative Review

    Psychotropic medication treatment can cause elevated serum prolactin levels and hyperprolactinaemia (HPRL). Reports have suggested that aripiprazole may decrease elevated prolactin. The aim of this review was to assess evidence for the efficacy of …

  9. Open Access 01-12-2020 | Hyperprolactinemia | OriginalPaper

    Cardiac valvular abnormalities associated with use and cumulative exposure of cabergoline for hyperprolactinemia: the CATCH study

    Most patients with persistent hyperprolactinemia have a prolactin-secreting pituitary prolactinoma and are generally treated with dopamine agonists (bromocriptine or cabergoline) which can effectively reduce prolactin secretion and size of the …

  10. 01-09-2019 | Erectile Dysfunction | OriginalPaper

    Hyperprolactinemia diagnosis in elderly men: a cohort of 28 patients over 65 years

    Prolactinoma, the most common functional pituitary adenoma, is usually diagnosed in males as a macroadenoma (diameter >10 mm) [ 1 , 2 ]. Symptoms of prolactinoma are related to hyperprolactinemia and tumor-mass effect on surrounding tissues. In …

  11. 01-06-2020 | Prolactinoma | ReviewPaper

    Hyperprolactinemia and bone

    Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a …

  12. 01-06-2020 | Hyperprolactinemia | OriginalPaper

    Hyperprolactinemia as a prognostic factor for menstrual disorders in female adolescents with advanced chronic kidney disease

    Women with chronic kidney disease (CKD) suffer from a variety of gynecological problems, which are frequently unrecognized [ 1 ]. For several years, CKD has been associated with neuroendocrine disorders, growth deceleration, and sexual dysfunction …

  13. 01-11-2019 | Hyperprolactinemia | OriginalPaper

    Impact of the CYP2D6 phenotype on hyperprolactinemia development as an adverse event of treatment with atypical antipsychotic agents in pediatric patients

    Treatment with atypical antipsychotic agents is indicated for first delirious psychotic episodes and schizophrenia. Clinical trials have shown their superiority to classical antipsychotic agents [ 1 ].

  14. Open Access 01-04-2019 | Schizophrenia | OriginalPaper

    A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia

    Schizophrenia is a serious polymorphic mental disorder, characterized by positive (e.g., hallucinations, delusions), negative (affective flattening, social withdrawal) and cognitive symptoms (disorders of attention, working memory deficits).

  15. 01-12-2016 | OriginalPaper

    Recurrence of hyperprolactinemia following dopamine agonist withdrawal and possible predictive factors of recurrence in prolactinomas

    Dopamine agonists, in particular CAB, are the primary therapy for prolactinomas. However, the optimal duration of treatment that minimizes recurrences is still object of debate in the literature [ 1 – 6 ].

  16. 01-07-2000 | Letter

    Hyperprolactinemia preceding Cushing’s disease

  17. 01-04-2003 | OriginalPaper

    Insulin sensitivity and hyperprolactinemia

    It has been shown that prolactin (PRL) induces glucose intolerance, hyperinsulinemia and insulin resistance in several animal species. In women with microprolactinomas, the sensitivity to insulin is lower in hyperprolactinemia than in …

  18. 01-01-2020 | Migraine | OriginalPaper

    Evidence for hyperprolactinemia in migraineurs: a systematic review and meta-analysis

    Migraine is characterized by recurrent headaches that are often throbbing in sensation and frequently unilateral in location and severe in intensity [ 1 , 2 ]. From the etiology aspects, it is thought that migraine is a form of neuro-vascular …

  19. 01-03-2005 | OriginalPaper

    Hyperprolactinemia affects spermiogenesis in adult male rats

    The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known …

  20. 01-05-2004 | OriginalPaper

    Metastatic renal cell carcinoma to the pituitary presenting with hyperprolactinemia

    Metastases to the pituitary gland from systemic cancers is a rare phenomenon and usually occurs in patients with disseminated disease. The neurohypophysis is the most commonly involved site, and diabetes insipidus is the most common presentation …

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