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Asbestosis 

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  1. Open Access 01-12-2022 | Hypersensitivity Pneumonitis | OriginalPaper

    High-resolution computed tomography features of asbestosis versus fibrotic hypersensitivity pneumonitis: an observational study

    Asbestos is a natural crystalline silicate mineral that has various commercial and industrial uses, such as in fire prevention and insulation. Asbestos is widely used in industrial production as well as in routine life; chrysotile fibers are the …

  2. Open Access 01-12-2023 | Asbestos-Related Disease | OriginalPaper

    Expression of microRNAs in leukocytes and serum of asbestosis patients

    Approximately 107,000 deaths occur due to asbestos-related diseases in Europe every year [ 1 ]. In the European Union (EU) 78% of occupational cancers were caused by asbestos exposure [ 2 ]. Although asbestos use has been prohibited in many …

  3. 01-12-2021 | Silicosis | Original Research

    Downregulation of the PD-1/PD-Ls pathway in peripheral cells correlates with asbestosis severity

    Interstitial lung disease (ILD), or diffuse parenchymal lung disease, is a group of diseases that appear in the lung interstitium and alveolar cavity, resulting in alveolar capillary dysfunction [ 1 ]. Pulmonary fibrosis is an advanced …

  4. Open Access 26-12-2022 | Computed Tomography | OriginalPaper

    Artificial intelligence-based diagnosis of asbestosis: analysis of a database with applicants for asbestosis state aid

    Asbestosis is diffuse pulmonary fibrosis emerging after prolonged, mainly occupational, exposure to asbestos [ 1 ]. Many countries have banned asbestos in construction and manufacturing [ 2 ]. However, due to the long incubation time, many (former) …

  5. Safety and tolerability of pirfenidone in asbestosis: a prospective multicenter study

    Asbestosis is a rare occupational interstitial lung disease, caused by inhalation of asbestos fibers [ 1 ]. Although the use of asbestos has been restricted or banned in many countries, global incidence of asbestosis has increased, including in …

  6. 01-05-2021 | Silicosis | OriginalPaper

    Costs of asbestosis and silicosis hospitalization in Italy (2001–2018)

    Costs of asbestosis and silicosis hospitalization

    Occupational lung diseases cause 70% of work-related mortality (Weston 2011 ). Asbestosis and silicosis are preventable fibrotic forms of pneumoconiosis, a lung disorder showing radiographic abnormalities. They are caused by cumulative inhalation …

  7. 01-08-2017 | OriginalPaper

    Correlation of ultra-low dose chest CT findings with physiologic measures of asbestosis

    Asbestosis is an interstitial lung disease (ILD) resulting from the inhalation of asbestos fibres. Traditionally asbestosis was diagnosed by symptoms, occupational history and parenchymal changes (profusion) on plain chest x-ray. High-resolution …

  8. Open Access 01-12-2009 | OriginalPaper

    Antemortem diagnosis of asbestosis by screening chest radiograph correlated with postmortem histologic features of asbestosis: a study of 273 cases

    Asbestosis is a disease of interstitial pneumonitis and fibrosis caused by the inhalation of asbestos fibers [ 1 ]. The antemortem diagnosis of abestosis is typically made on clinical grounds without the aid of histologic evidence [ 2 ]. The …

  9. Open Access 01-12-2017 | OriginalPaper

    Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case–control study

    Asbestosis and silicosis are progressive pneumoconioses characterized by interstitial fibrosis following exposure to asbestos or silica dust. Disease progression usually leads to irreversible complications and death. Clinical detection and …

  10. 01-05-2016 | OriginalPaper

    Asbestosis and other pulmonary fibrosis in asbestos-exposed workers: high-resolution CT features with pathological correlations

    Asbestosis is suspected when diffuse lung fibrosis is identified in patients with clinical evidence of vast amounts of asbestos exposure. However, it is not only asbestosis that presents with diffuse lung fibrosis in such patients, but also …

  11. Open Access 01-12-2015 | OriginalPaper

    Systemic autoimmune disease in asbestosis rapidly responding to anti-interleukin-1beta antibody canakinumab: a case report

    Asbestosis is a progressive interstitial lung disease caused by inhalation of asbestos fibers occurring in subjects with prolonged exposure to asbestos dust, such as miners, quarrymen, millers, workers of asbestos textiles and insulators.

  12. 01-10-1998 | OriginalPaper

    Follow-up of asbestosis patients and predictors for radiographic progression

    Objective: We followed a group of 85 Finnish asbestosis patients radiographically for an average of 6.5 (range 2–10) years to examine the progression of the disease and to assess possible explanations for the progression. Methods: The examinations …

  13. Open Access 01-12-2012 | OriginalPaper

    Cryptococcus pneumonia presenting in an immunocompetent host with pulmonary asbestosis: a case report

    The pathogenic role of asbestos exposure prior to the development of pulmonary cryptococcal infections is not well defined. A few clinical reports [ 1 – 3 ] have linked asbestos exposure and pulmonary aspergillosis. None of the case reports with …

  14. 01-03-2002 | OriginalPaper

    Mechanisms of Colchicine Effect in the Treatment of Asbestosis and Idiopathic Pulmonary Fibrosis

    The objective of this study was to evaluate the mechanisms of colchicine action in pulmonary fibrosis. The study included 10 patients with pulmonary fibrosis (idiopathic pulmonary fibrosis 5, asbestosis 4, and scleroderma 1) who had been admitted …

  15. 01-02-2008 | OriginalPaper

    A case of pulmonary asbestosis presenting with temporal arteritis involving multiple medium-sized vessels

    A 76-year-old woman with pulmonary asbestosis was admitted with fever and polymyalgia. She subsequently developed a visual disorder, hemoptysis, and hemoperitoneum. A biopsy of the temporal artery revealed the presence of giant-cell arteritis. CT …

  16. 01-01-1997 | OriginalPaper

    Immunohistochemical localization of transforming growth factor-β and insulin-like growth factor-I in asbestosis in the sheep model

    Asbestosis is characterized by increased collagen deposition along the walls of terminal respiratory bronchioles that extends into the alveolar ducts and septae. Alveolar macrophages are activated and release growth factors that stimulate …

  17. Open Access 01-12-2010 | OriginalPaper

    Mesothelioma and asbestosis in a young woman following occupational asbestos exposure: Short latency and long survival: Case Report

    A 27-year-old female white-collar worker was diagnosed in 1998 with mesothelioma eight and one-half years following first exposure as a bystander to debris in a site in which asbestos-containing building materials were being dismantled and …

  18. Open Access 01-12-2024 | Mesothelioma | OriginalPaper

    Global, regional, and national burden of non-communicable diseases attributable to occupational asbestos exposure 1990–2019 and prediction to 2035: worsening or improving?

    Understanding the burden associated with occupational asbestos exposure on a global and regional scale is necessary to implement coordinated prevention and control strategies. By the GBD Study 2019, we conducted a comprehensive assessment of the …

  19. Open Access 01-12-2023 | Nintedanib | OriginalPaper

    Interstitial lung disease related to occupational hard metal exposure: two case reports

    Well-known occupation-related interstitial lung diseases (ILD) include silicosis, asbestosis, and coal workers’ pneumoconiosis [ 1 ]. Hard metal lung disease (HMLD) is a relatively less known but important cause of occupational ILD. Hard metals are …

  20. 28-10-2023 | Asbestos-Related Disease | ReviewPaper

    Asbestos-related lung disorders

    Exposure to asbestos is associated with various pathologies, such as asbestosis, mesothelioma, and pleural plaques. As treatment for these disorders is not curative, the main aim should be to limit exposure.

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