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Silicosis 

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  1. Open Access 01-12-2024 | Silicosis | OriginalPaper

    Latent tuberculosis infection and infection-associated risk factors for miner workers with silicosis in eastern China

    Silicosis is a fibrotic lung disease caused by inhalation of free crystalline silicon dioxide or silica [ 1 ] . While silicosis is the most main and severe occupational disease in China. From 1990 to 2019, new incident silicosis cases in China …

  2. Open Access 01-12-2024 | Silicosis | OriginalPaper

    Burden of silica-attributed pneumoconiosis and tracheal, bronchus & lung cancer for global and countries in the national program for the elimination of silicosis, 1990–2019: a comparative study

    Crystalline silica, being among the Earth’s most abundant minerals, serves as a crucial constituent of soil, sand, and granite [ 1 ]. Exposure to crystalline silica is omnipresent in the environment, encompassing not only natural phenomena like …

  3. Open Access 15-09-2023 | Silicosis | OriginalPaper

    Clinical characteristics of systemic sclerosis patients with occupational silicosis

    To explore the clinical characteristics of systemic sclerosis complicated with silicosis. The systemic sclerosis patients treated in the Guangxi Workers’ Hospital and the People's Hospital of Guangxi Zhuang Autonomous Region from January 2000 to …

  4. Open Access 01-12-2023 | Silicosis | ReviewPaper

    Challenges and opportunities for silicosis prevention and control: need for a national health program on silicosis in India

    Silicosis is an irreversible and fatal pneumoconiosis affecting millions of workers worldwide who are exposed to silica dust [ 1 ]. Mining, tunneling, quarrying, sculpturing, foundries, and manufacturing of building construction materials are some …

  5. 17-04-2023 | Silicosis | OriginalPaper

    Exploratory study on noninvasive biomarker of silicosis in exhaled breath by solid-phase microextraction–gas chromatography–mass spectrometry analysis

    Silicosis is one of the most widespread occupational diseases which is characterized by pulmonary inflammation and scar-forming nodular fibrosis. It is widely recognized that silicosis is caused by exposure to respirable crystalline silica (RCS) …

  6. Open Access 01-12-2023 | Silicosis | OriginalPaper

    Silicosis as a predictor of tuberculosis mortality and treatment failure and need for incorporation in differentiated TB care models in India

    In 2021, there were 6.4 million reported cases and 1.6 million deaths due to tuberculosis (TB) worldwide [ 1 ]. India had the highest number of reported TB cases at 2.42 million and the highest number of reported TB deaths at 0.5 million in 2022 [ …

  7. Open Access 01-12-2022 | Silicosis | OriginalPaper

    The significance of serum S100 calcium-binding protein A4 in silicosis

    Silicosis is one of the most common occupational diseases caused by the chronic inhalation of large amounts of respirable crystalline silica from the environment [ 1 , 2 ]. Characteristic pathology in silicosis consists of persistent inflammation …

  8. Open Access 01-12-2023 | Silicosis | OriginalPaper

    Microbiota and mycobiota in bronchoalveolar lavage fluid of silicosis patients

    Silicosis, a common type of pneumoconiosis, is a work-related fibrotic lung disease usually caused by occupational exposure to respirable crystalline silica and hazardous dust [ 1 ]. Crystalline silica is a common component of the earth’s crust and …

  9. Open Access 01-12-2023 | Silicosis | OriginalPaper

    Global incidence, prevalence and disease burden of silicosis: 30 years’ overview and forecasted trends

    Silicosis is a typical pneumoconiosis and common in workers who have large chances to be exposed to free crystalline silica (SiO 2 ) during long-term occupational activities [ 1 ]. Generally, silicosis is characterized by the development of …

  10. Open Access 01-12-2022 | Silicosis | OriginalPaper

    Global and national burden and trends of mortality and disability-adjusted life years for silicosis, from 1990 to 2019: results from the Global Burden of Disease study 2019

    Silicosis is a major type of pneumoconiosis, caused by inhalation of silica particles or free crystalline silicon dioxide [ 1 ], which exist in the air of both living and working environments [ 2 ]. Generally, silicosis leads to progressive and …

  11. Open Access 01-12-2021 | Silicosis | OriginalPaper

    Distinct metabolic features in the plasma of patients with silicosis and dust-exposed workers in China: a case–control study

    Silicosis is a progressive pneumoconiosis characterized by nodular interstitial fibrosis following exposure to silica dust [ 1 ]. Disease progression of silicosis usually leads to irreversible complications and death. As observed in a recent …

  12. Open Access 01-12-2022 | Tuberculosis | OriginalPaper

    The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis

    Tuberculosis is a common and serious complication of silicosis. The probability of concurrent pulmonary tuberculosis at the time of phase I–II disease is 10–30%. When silicosis enters phase III, tuberculosis occurs in 50–90% of patients, and 45% …

  13. Open Access 01-12-2021 | Silicosis | OriginalPaper

    Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis

    Silicosis is a pulmonary interstitial fibrosis disease caused by the exposure to crystalline silica dust. This disease is a progressive process characterized by lung inflammation during the early phase and triggering pulmonary fibrosis with …

  14. 01-04-2022 | Tuberculosis | OriginalPaper

    Comparison of Silicosis and Tuberculosis Involving Mediastinal Lymph Nodes Based on Contrast-Enhanced Multidetector-Row Computed Tomography

    Silicosis is one of the greatest prevailing occupational diseases in the world [ 1 ]. Even though efforts have been made in the past decades to prevent silicosis, its incidence rate is still increasing worldwide [ 2 , 3 ]. The development of …

  15. 01-10-2021 | Silicosis | OriginalPaper

    Silicon, an important exposure marker in vivo in silicosis research

    Exposure to respirable crystalline silica dusts is very common in a multitude of industries and occupational settings. Inhalation of fine silica, including their most abundant naturally occurring polymorphs quartz and cristobalite, can lead to …

  16. Open Access 01-12-2021 | Tuberculosis | OriginalPaper

    The association between silica exposure, silicosis and tuberculosis: a systematic review and meta-analysis

    Occupational silica exposure continues to occur in almost all countries and in many industries and occupations: construction, agriculture and mining being among the largest employers. Consequently, millions of individuals are at risk of …

  17. 01-09-2021 | Silicosis

    Current Concepts in Pathogenesis, Diagnosis, and Management of Silicosis and Its Subtypes

    Silicosis is an occupational lung disease caused by the inhalation of crystalline silica [ 1 , 2 ••]. Silicon dioxide (silica) is a very common mineral and exists in both amorphous and crystalline forms [ 3 ]. Inhalational exposure to crystalline …

  18. 01-05-2021 | Silicosis | OriginalPaper

    Costs of asbestosis and silicosis hospitalization in Italy (2001–2018)

    Costs of asbestosis and silicosis hospitalization

    Occupational lung diseases cause 70% of work-related mortality (Weston 2011 ). Asbestosis and silicosis are preventable fibrotic forms of pneumoconiosis, a lung disorder showing radiographic abnormalities. They are caused by cumulative inhalation …

  19. 01-12-2020 | Tuberculosis

    Predictors of silicosis and variation in prevalence across mines among employed gold miners in South Africa

    Silicosis, fibrosis of the lung due to inhalation of silica containing dust, remains a disease of the modern age [ 1 ]. Silicosis continues to be reported from traditional extractive and industrial operations in Brazil [ 2 ], China [ 3 ], India [ 4 …] and Zambia [

  20. 01-08-2018 | Report

    EBUS-TBNA is Sufficient for Successful Diagnosis of Silicosis with Mediastinal Lymphadenopathy

    Silicosis is a progressive, fibrotic, occupational lung disease resulting from inhalation of respirable crystalline silica, which is preventable through appropriate workplace practices [ 1 , 2 ]. Mineral sources of silica are abundant and include …

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