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2676 search results for:

AT1 Receptor Antagonist 

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"newest" sorts results by publication date. "most relevant" also considers factors like how often the search phrase is in the result.
  1. 01-05-2024 | Ivabradine | News

    Beta-adrenergic-receptor-antagonists/Ivabradine

    Lack of efficacy
  2. 01-05-2024 | News

    Lenvatinib/Programmed-cell-death-1-receptor-antagonists

    Hypothyroidism
  3. 01-05-2024 | Verapamil | News

    Beta-adrenergic-receptor-antagonists/Verapamil

    Dyssynchronous right ventricular pacing
  4. 01-05-2024 | Methimazole | News

    Iodine-radioactive/thiamazole/unspecified beta adrenergic receptor antagonists

    Lack of efficacy
  5. 25-04-2024 | Finerenone | Online First

    Intellectual landscapes and emerging trends of non-steroidal mineralocorticoid receptor antagonists: a bibliometric and visual analysis

    The mineralocorticoid receptor (MR) belongs to the nuclear hormone receptors that has been found to be abundantly expressed in various cells and tissues, particularly the heart, kidneys, and vasculature. Prior studies have suggested that the MR …

  6. 01-03-2024 | Tachyarrythmia | News

    Flecainide/β-adrenergic-receptor-antagonists

    Lack of efficacy
  7. 01-06-2024 | Oxybutynin | OriginalPaper

    A muscarinic receptor antagonist reverses multiple indices of diabetic peripheral neuropathy: preclinical and clinical studies using oxybutynin

    Preclinical studies indicate that diverse muscarinic receptor antagonists, acting via the M1 sub-type, promote neuritogenesis from sensory neurons in vitro and prevent and/or reverse both structural and functional indices of neuropathy in rodent …

  8. Open Access 17-01-2024 | Parkinson's Disease | Letter

    New insights on the potential effect of orexin receptor antagonist suvorexant on Parkinson’s disease symptoms

  9. 01-01-2024 | Pruritus | News

    Histamine-H1-receptor-antagonists/histamine-H2-receptor-antagonists/methylprednisolone

    Lack of efficacy
  10. 27-04-2024 | Nausea | Online First

    Gene polymorphisms of TACR1 serve as the potential pharmacogenetic predictors of response to the neurokinin-1 receptor antagonist-based antiemetic regimens: a candidate-gene association study in breast cancer patients

    Chemotherapy-induced nausea and vomiting (CINV), one of the most feared, debilitating, and common adverse events of moderately and highly emetogenic chemotherapy administration, is still troubling patients by reducing their quality of life and …

  11. Open Access 06-02-2024 | OriginalPaper

    Cardiovascular Events with the Use of Long-Acting Muscarinic Receptor Antagonists: An Analysis of the FAERS Database 2020–2023

    Long-acting muscarinic receptor (mAChR) antagonists (LAMAs), given as monotherapy or in combination with a long-acting β 2 -agonist (LABA) and, often, an inhaled corticosteroid (ICS), are widely prescribed for the treatment of chronic obstructive …

  12. Open Access 01-12-2024 | Guillain-Barré Syndrome | OriginalPaper

    P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation

    Guillain–Barré syndrome (GBS) is an acute inflammatory polyneurogenic disease that can lead to motor dysfunction, sensory impairment, autonomic dysfunction, and respiratory failure [ 1 , 2 ]. Effective treatments for these ailments include plasma …

  13. 08-03-2024 | Tamsulosin | Online First

    Effect of different alpha-receptor antagonists on metabolic parameters: a head-to-head comparison

    It is well established that the metabolic and blood pressure-lowering effects of antihypertensives should be considered for treating hypertension. Alpha-receptor antagonists, angiotensin-converting enzyme inhibitors, and angiotensin receptor

  14. Open Access 01-12-2024 | Glioblastoma | OriginalPaper

    Combining a noble gas with radiotherapy: glutamate receptor antagonist xenon may act as a radiosensitizer in glioblastoma

    A complex system promoting glioma invasion and growth has been recently discovered in several studies: By forming synapses with astrocytes, glioma cells receive proliferative stimuli that are passed on through tumor cell networks as depolarizing …

  15. Open Access 08-02-2024 | Pharmacokinetics | OriginalPaper

    Pharmacokinetics of the Novel Nonsteroidal Mineralocorticoid Receptor Antagonist Ocedurenone (KBP-5074) in Individuals with Moderate Hepatic Impairment

    The selective inhibition of mineralocorticoid receptors (MRs) is a validated therapeutic approach providing blood pressure control via a mechanism distinct from other antihypertensive agents [ 1 , 2 ]. In patients with chronic kidney disease (CKD) …

  16. 12-02-2024 | OriginalPaper

    Effect of Gonadotropin-Releasing Hormone Antagonist on the Expression Patterns of Insulin-Like Growth Factor 1, Androgen Receptor, and Luteinizing Hormone Receptor in an Experimental Rat Model of Functional Ovarian Cysts

    We studied the expression of insulin-like growth factor 1 (IGF-1), androgen receptor (AR) and luteinizing hormone receptor (LHR) in the ovaries under the conditions of the modeling and subsequent treatment of functional ovarian cysts with …

  17. 10-01-2024 | Pharmacokinetics | OriginalPaper

    Safety and Pharmacokinetics of HRS-2261, a P2X3 Receptor Antagonist, in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study

    Chronic cough, defined as a persistent cough lasting over 8 weeks, presents a substantial clinical challenge within the field of respiratory medicine [ 1 – 3 ]. Its prevalence is remarkably high, impacting a considerable proportion of the global …

  18. Open Access 30-01-2024 | Clostridioides Difficile | OriginalPaper

    Association Between Risk of Clostridium difficile Infection and Duration of Proton Pump Inhibitor or H2-Receptor Antagonist Use in Hospitalized Patients

    Clostridium difficile is one of the common causes of nosocomial infection in hospitals and is associated with high morbidity and mortality [ 1 – 3 ]. Clinical signs and symptoms of C. difficile infection (CDI) include severe to life-threatening …

  19. Open Access 07-03-2024 | Radionuclide Therapy | Online First

    First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum

  20. Open Access 01-12-2024 | Esophageal Cancer | OriginalPaper

    NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route

    Esophageal cancer (EC) is a type of epithelial cancer characterized by NY-ESO-1 expression with an increasing re-expression level in EC tissues, making the usage of autologous or allogeneic T cells engineered to express TCRs that target NY-ESO-1 …

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