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  1. Open Access 01-12-2023 | Osteosarcoma | OriginalPaper

    Exploratory study of an anti-PD-L1/TGF-β antibody, TQB2858, in patients with refractory or recurrent osteosarcoma and alveolar soft part sarcoma: a report from Chinese sarcoma study group (TQB2858-Ib-02)

    Sarcomas are a rare, heterogeneous family of mesenchymal tumors, most of which are in an immunosuppressive state, with fewer responses to immune checkpoint inhibition than other adult tumors [ 1 ]. Among these tumors, osteosarcomas are …

  2. 31-10-2023 | Lymphadenopathy | Letter

    Reply to comment to “axillary lymph nodes enlargement after Sars-CoV-2 vaccine in patients undergoing breast examination: a single-centre experience in 285 women”

  3. 25-08-2023 | Lymphadenopathy | OriginalPaper

    Axillary lymph nodes enlargement after Sars-CoV-2 vaccine in patients undergoing breast examination: a single-centre experience in 285 women

    During the COVID-19 pandemic, the vaccination campaign has led to an increase of detected lymphadenopathy, particularly in the axilla ipsilateral to the injection site [ 1 ]. This could represent a diagnostic challenge: on the one hand it may …

  4. Open Access 01-12-2022 | Spinal Muscular Atrophy | OriginalPaper

    Post‐dural puncture headache: a prospective study on incidence, risk factors, and clinical characterization of 285 consecutive procedures

    Post-dural puncture headache (PDPH), formerly known as post-lumbar puncture headache, is a well-known adverse event that follows diagnostic and/or therapeutic puncture of the dura, or accidentally, following spinal anesthesia [ 1 ]. The classical …

  5. Open Access 12-07-2022 | Seminoma | OriginalPaper

    Oncological and functional outcomes after testis-sparing surgery in patients with germ cell tumors: a systematic review of 285 cases

    In several urogenital cancers, organ-preserving surgery represents the preferred treatment approach. In men with a testicular germ cell tumors (tGCT), radical orchiectomy is the standard of care. Testis-sparing surgery (TSS) potentially reduces …

  6. 01-06-2021 | Diabetes | OriginalPaper

    Significant association of LXRβ (NR1H2) polymorphisms (rs28514894, rs2303044) with type 2 diabetes mellitus and laboratory characteristics

    Type 2 diabetes mellitus (T2DM) is a fast-growing chronic metabolic and endocrine disorder substantially influencing human life and health expenditures [ 1 ]. In 2017, it was estimated that more than 460 million people were affected by T2DM …

  7. Open Access 01-12-2020 | OriginalPaper

    The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study

    In spite of health warnings, the consumption of sugar remains high worldwide. Dietary sugar takes different forms—solid or liquid, naturally occurring or added and intrinsic or extrinsic to cells—and different chemical compositions such as glucose …

  8. 01-12-2020 | Lymphoma

    Allogeneic stem cell transplantation for peripheral T cell lymphomas: a retrospective study in 285 patients from the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC)

    Peripheral T cell lymphomas (PTCL) form a heterogeneous group of rare lymphomas [ 1 ], with a usually dismal prognostic.

  9. Open Access 01-12-2019 | NSCLC | OriginalPaper

    Association of newly identified genetic variant rs2853677 of TERT with non-small cell lung cancer and leukemia in population of Jammu and Kashmir, India

    Lung cancer has highest mortality rate among cancers for both males and females, whereas males are more affected than females in leukemia by the ratio 1:5:1:0 [ 1 ]. Both the cancers are aggressive in nature, and this is one of the major global …

  10. 01-06-2021 | Pharmacokinetics | OriginalPaper

    Pharmacokinetics of Roxadustat: A Population Analysis of 2855 Dialysis- and Non-Dialysis-Dependent Patients with Chronic Kidney Disease

    Roxadustat is a new chemical entity and first in a new pharmacologic class of small-molecule therapeutics that stimulate erythropoiesis by inhibiting hypoxia-inducible factor prolyl hydroxylase enzymes. Its ability to stimulate erythropoiesis …

  11. Open Access 25-07-2022 | OriginalPaper

    The use of a modified posterior approach (SPAIRE) may be associated with an increase in return to pre-injury level of mobility compared to a standard lateral approach in hemiarthroplasty for displaced intracapsular hip fractures: a single-centre study of the first 285 cases over a period of 3.5 years

    Displaced intracapsular hip fracture patients are treated with arthroplasty, most frequently being a hemiarthroplasty [ 1 ]. Mobility and functional independence have been reported to be the main priority for hip fracture patients [ 2 ].

  12. 01-01-2020 | Achilles Tendon Rupture | OriginalPaper

    Understanding limitations in sport 1 year after an Achilles tendon rupture: a multicentre analysis of 285 patients

    Achilles tendon ruptures are more commonly sustained by males than females. The injury occurs when participating in sporting activities such as netball, badminton, tennis, squash, rugby or football, but it can also occur when an individual falls …

  13. 01-03-2022 | OriginalPaper

    A study of 285 cases of cranial vault suture closure in Chinese adults

    The skull is the most complex skeletal structure in the human body. The skull of a young adult consists of 28 separate flat and irregular bones, most of which are connected by "cranial sutures" [ 19 ]. The coronal suture, sagittal suture, and …

  14. Open Access 01-02-2021 | OriginalPaper

    Prevalence and morphological changes of carotid kinking and coiling in growth: an echo-color Doppler study of 2856 subjects between aged 0 to 96 years

    Extracranial internal carotid artery (EICA) kinking and coiling are the most frequently reported carotid anomalies in the literature. Embryogenic and acquired causes for such anomalies have been postulated but the prevalence of kinking and coiling …

  15. 01-09-2019 | Hemolytic Anemia | Letter

    Hb Fairfax [HBB:c.285_286insGAGCTGCACTGTGAC] in a Brazilian patient with severe hemolytic anemia—identification and functional study

  16. Open Access 01-12-2014 | OriginalPaper

    MDM2 285G>C and 344T>A gene variants and their association with hepatocellular carcinoma: a Moroccan case–control study

    Hepatocellular carcinoma (HCC), is the most frequent primary liver tumor, with a high incidence in Africa and Asia, which makes it the fifth human malignancy and the third most common cause of cancer-related mortality[ 1 , 2 ]. It is well …

  17. Open Access 01-08-2015 | OriginalPaper

    Murine Double-Minute 2 Homolog Single Nucleotide Polymorphisms 285 and 309 in Cervical Carcinogenesis

    Cervical tumors are the third most frequent type of neoplasia that causes death among women worldwide [ 1 ]. The incidence of cervical neoplasia is especially high in developing countries, accounting for 86 % of all newly diagnosed cases worldwide …

  18. Open Access 01-12-2018 | OriginalPaper

    Association between acromegaly and a single nucleotide polymorphism (rs2854744) in the IGFBP3 gene

    With a prevalence of 14–22%, pituitary adenoma is one of the most common intracranial neoplasms. An increasing number of pituitary surgeries are performed in our hospital. Somatotroph adenomas, which constitute the commonly diagnosed secreting …

  19. 01-06-2018 | OriginalPaper

    LOC285629 regulates cell proliferation and motility in colorectal cancer cells

    Colorectal cancer (CRC) has become the epitome of cancers that are highly associated with death. Being the third most commonly diagnosed cancer and leading cause of cancer-related deaths worldwide, CRC has attracted a lot of attention among …

  20. 01-07-2018 | EditorialNotes

    Neurological sciences impact factor 2017 is increased to 2.285: a comment from the Editor in Chief

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