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Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

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Cerebrovascular Disease Stroke

Stroke

Long-term outcomes after giant cavernous sinus hemangioma

Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection. 

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Editor's Choice

Autonomic dysfunction after stroke

Central autonomic dysfunction is common in acute stroke and is associated with cardiovascular complications and increased mortality. But novel diagnostic and therapeutic approaches could help manage this disorder.

Cardiovascular event risk heightened by amaurosis fugax diagnosis

Transient vision loss due to vascular causes puts people at significant risk for having a future stroke, carotid stenosis, or transient ischemic attack.

Framework for decannulation in neurological patients

Decannulation is often complicated by severe dysphagia, reduced cough strength, excessive bronchial secretions, and altered airway anatomy. What diagnostic procedures and therapeutic options are crucial for rehabilitation?

Late-window thrombolysis feasible for mild ischemic stroke

Alteplase treatment 4.5–24 hours after posterior circulation stroke in patients who did not have thrombectomy may improve the chances of functional independence compared with standard medical care.

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Keynote webinar | Spotlight on sleep in brain health

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Renata Riha
Dr. Sven Rupprecht
Developed by: Springer Medicine
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Video

Latest News

The earlier the better for DOAC initiation in stroke patients with AF

Cardiovascular event risk heightened by amaurosis fugax diagnosis

Late-window thrombolysis feasible for mild ischemic stroke

Target stroke patients for nerinetide neuroprotection identified

Decreased stroke risk with DOAC may be offset by increased chance of bleeding

TIA linked to cognitive decline risk

Case Studies

Long-term outcomes after giant cavernous sinus hemangioma

Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection. 

Cryptogenic stroke associated with pulmonary arteriovenous fistula

  • Open Access
  • Stroke
  • Case Study

In this unusual case, OCT revealed multiple mural thrombi in a PAVF as the source of embolic strokes and continuing ischemic attacks, indicating a potential emboligenic mechanism in PAVF.

Cholesterol crystal embolization following alteplase for stroke

CCE led to multiorgan failure and death after intravenous alteplase to treat acute ischemic stroke. This case highlights the urgent need for greater awareness of this serious complication.

Episode 8: AI in stroke

About 50% of stroke patients have an unfavorable outcome. Predicting outcome is challenging but is key to understanding how best to treat patients.

Prof Susanne Wegener discusses her team’s work to develop deep learning models that outperform neurologists when predicting outcome based on imaging data alone or in combination with clinical data.

Prof. Dr. Susanne Wegener
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Podcast

Current Reviews

Combined Catheter Ablation and Left Atrial Appendage Occlusion in Atrial Fibrillation: From Data to Clinical Reality

Atrial fibrillation (AF), the most common cardiac arrhythmia, is well-known for its threatening complications, with the most significant being ischemic stroke. While the stroke risk is usually managed with oral anticoagulant treatment (OAC) …

Percutaneous left atrial appendage closure for stroke prevention: current challenges and future perspectives

Stroke accounts for significant morbidity and mortality worldwide. Accordingly, appropriate prevention is crucial to reduce the global burden of stroke. Percutaneous left atrial appendage closure (LAAC) is a viable approach for preventing …

Intracranial atherosclerotic plaque features on vessel wall imaging predict first ever and recurrence of stroke: a meta-analysis

Intracranial atherosclerosis disease (ICAD) is a major cause of ischemic stroke [ 1 , 2 ]. The annual risk of stroke recurrence is as high as 10–24% in symptomatic ICAD patients despite aggressive pharmacologic therapy and control of associated …

Intrathecal Nicardipine After Aneurysmal Subarachnoid Hemorrhage: A Scoping Review

Intrathecal nicardipine (ITN) is an investigational therapy for cerebral vasospasm (CVS) and delayed cerebral ischemia (DCI) in patients with aneurysmal subarachnoid hemorrhage (aSAH). The objective of this scoping review was to characterize the …

Episode 4: Stem cell therapy for PD

A new era for managing Parkinson’s disease?

STEM-PD, the first in-human safety trial of stem cell therapy for Parkinson’s disease, began this year and marks a huge step forward for this type of treatment.

We talk to Prof. Malin Parmar about why stem cell therapy is such a good option for patients with Parkinson’s disease and get an update on the current status of the trial.

Dr. Malin Parmar
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Podcast

Further Reading

Combined Catheter Ablation and Left Atrial Appendage Occlusion in Atrial Fibrillation: From Data to Clinical Reality

Atrial fibrillation (AF), the most common cardiac arrhythmia, is well-known for its threatening complications, with the most significant being ischemic stroke. While the stroke risk is usually managed with oral anticoagulant treatment (OAC) …

CILO-CLOP Trial: Cilostazol Versus Clopidogrel in Acute Moderate and Moderate-to-Severe Ischemic Stroke: A Randomized Controlled Multicenter Trial

Antiplatelet medications are the most important agents for reducing the risk of recurrent stroke, myocardial infarction, and other vascular occlusive syndromes that develop after ischemic stroke [ 1 , 2 ]. Non-cardioembolic moderate and …

Hydroxysafflower yellow A alleviates the inflammatory response in astrocytes following cerebral ischemia by inhibiting the LCN2/STAT3 feedback loop

Lipocalin-2 (LCN2), an acute phase protein mainly expressed in astrocytes (Ast), is closely related to the production of inflammatory cytokines following ischemic stroke. During the pathophysiological process of ischemic stroke, the Janus kinase …

DWI Reversibility in Acute Ischemic Stroke Due to Basilar Artery Occlusion Following Successful Recanalization

Endovascular stroke treatment (EVT) has become a standard treatment for posterior circulation acute ischemic stroke (AIS) caused by basilar artery thrombosis. Magnetic resonance imaging (MRI) is a well-established technique to evaluate the …

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