Skip to main content


Editor's Choice

Carotid free-floating thrombus stemming from carotid web

Open Access Stroke Case Study

The co-occurrence of two rare but critical causes of ischemic stroke. Meticulous evaluation of non-invasive and invasive vascular imaging tests detected a carotid free-floating thrombus originating from a contiguous carotid web.

Guidelines for determining neurological prognosis in critically ill adults with ICH

Open Access Cerebral Hemorrhage Guideline

Recommendations on the reliability of key predictors of neurological outcome in intracerebral hemorrhage to aid clinicians in formulating a prognosis and counseling patients and their family members.

Neurological complications of hereditary bleeding disorders

Hemophilia and von Willebrand disease can predispose patients to life-threatening CNS complications, particularly intracranial or intraspinal hemorrhage and peripheral nerve syndromes. Clinical manifestations and management of these neurological complications are discussed.

Current Reviews

Ten-year outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for multivessel or left main coronary artery disease: a systematic review and meta-analysis

Open Access Stroke Review

In the past few decades, several randomized clinical trials (RCTs) have compared percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) in patients with multiple vessels coronary artery disease (MVCA) or left main …

Managing high-risk atrial fibrillation patients with multiple comorbidities

Open Access Atrial Fibrillation Review

Atrial fibrillation (AF) patients are often high risk being elderly and having multiple comorbidities. Many risk factors are established to be associated with new onset incident AF, as well as AF-related complications such as stroke and …

The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis

Open Access Stroke Review

A stroke is an acute neurologic condition that occurs due to a disruption of cerebral perfusion, resulting in focal or global neurological impairment [ 1 ]. Strokes can be broadly classified into ischemic strokes (IS) and hemorrhagic strokes (HS).

Functional genomics in stroke: current and future applications of iPSCs and gene editing to dissect the function of risk variants

Open Access Stroke Review

Stroke is an important disease with unmet clinical need. To uncover novel paths for treatment, it is of critical importance to develop relevant laboratory models that may help to shed light on the pathophysiological mechanisms of stroke. Induced …

Case Studies

Recurrent embolic strokes due to antiphospholipid syndrome and non-bacterial thrombotic endocarditis in a patient with basal cell carcinoma

Open Access Stroke Case Study

Non-Bacterial Thrombotic Endocarditis (NBTE), also known as marantic endocarditis, outside of autoimmune disease and malignancies, is a rare disease with a prevalence of 0.9–1.6% that was described by Ziegler in 1888 as thromboendocarditis [ 1 ].

Cerebellar hematoma in severe hemophilia with inhibitor on emicizumab prophylaxis: a case report

Open Access Hemophilia Case Study

Hemophilia is a rare congenital, recessive X-linked disorder resulting from coagulation factor deficiency. Hemophilia A, the most common type, is characterized by a deficiency in the blood clotting factor VIII (FVIII). According to the World …

Hemichorea secondary to isolated temporal infarction with severe middle cerebral artery stenosis: a case report and review of literature

Open Access Computed Tomography Case Study

Hemichorea is defined as a syndrome characterized by continuous, irregular, and involuntary jerky movements on one side of the body. Its pathogenesis can originate from infections, immune reaction, metabolic abnormalities, malignancy …

Our tailored content service will keep you up to date…

Receive newsletters curated for the busy specialist by our expert editorial team

Further Reading

Multiple Hypointense Vessels are Associated with Cognitive Impairment in Patients with Single Subcortical Infarction

Open Access Cerebral Small Vessel Disease Research

We aimed to explore the relationship between multiple hypointense vessels and cognitive function in patients with single subcortical infarction (SSI) and the role of SSI with different etiological mechanisms in the above relationship. Multiple …

Perfusion deficits in thrombolysis-treated acute ischemic stroke patients with negative or positive diffusion-weighted imaging

Open Access Stroke Research

Intravenous tissue-type plasminogen activator (IV t-PA) was administered to acute ischemic stroke (AIS) patients after screening with a head CT to exclude intracerebral hemorrhage. Magnetic resonance imaging (MRI) with diffusion weighted imaging …

Prevalence and factors associated with pre-hospital delay among acute stroke patients at Mulago and Kiruddu national referral hospitals, Kampala: a cross-sectional study

Open Access Stroke Research

The incidence of stroke has declined in high income countries (HIC) over the past two decades, while rising in low- and middle-income countries (LMICs) [ 1 ]. Worse still, LMICs have poor stroke outcomes compared to HIC with LMICs accounting for …

Factors associated with the effectiveness of immersive virtual therapy in alleviating depressive symptoms during sub-acute post-stroke rehabilitation: a gender comparison

Open Access Stroke Research

Virtual reality (VR) is usually associated with entertainment, but it is also increasingly used in rehabilitation [ 1 ]. The rapidly changing world has made life faster and our habits and preferences have changed. Methods that were effective at the …