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Accumulating data suggest excessive oxygen use in brain-injured ICU patients contributes to secondary brain injury. The optimal oxygenation approach remains uncertain, but clinicians must balance the competing risks of hypoxemia and hyperoxemia.
Intravenous tenecteplase thrombolysis within 24 hours of stroke onset improves functional outcomes versus standard medical treatment in patients with basilar artery occlusion.
Giving the antibiotic minocycline to patients with acute ischemic stroke within 72 hours of symptom onset significantly improves functional outcomes at 90 days without increasing the risk for adverse events.
Tenecteplase thrombolysis is no more effective than aspirin for treating acute central retinal artery occlusion, and is associated with safety concerns.
Stroke-like episodes are an important clinical phenotype of neuronal intranuclear inclusion disease, but these cases are prone to misdiagnosis as acute stroke. Explore the most common clinical and imaging features of NIID.
New MRI contrast agents are reshaping diagnostic imaging, promising lower gadolinium exposure amid evolving practice guidelines. How can you optimise contrast selection, dosing, and patient care in this rapidly advancing field?
This content is intended for healthcare professionals outside of the UK.
Stroke-like episodes are an important clinical phenotype of neuronal intranuclear inclusion disease, but these cases are prone to misdiagnosis as acute stroke. Explore the most common clinical and imaging features of NIID.
This case study highlights a promising approach for pediatric acute ischemic stroke: ultra-early IV tenecteplase thrombolysis followed by targeted intra-arterial tirofiban to tackle large vessel occlusion.
Hypertrophic olivary degeneration is commonly caused by cerebral infarction. This case indicates that HOD should be considered in patients with a history of brainstem infarction who have new or progressively worsening symptoms.
Newcomer PACAP could make the difference in migraine control
Anti-CGRP therapy has dramatically improved migraine treatment for many patients since its introduction in 2018. However, 30–40% of patients do not respond adequately to these drugs.
Prof. Messoud Ashina talks to us about PACAP and why targeting this pathway could offer a new future option for such patients.
The potential benefit of patent foramen ovale device closure (PFOC) in reducing the risk of recurrent ischemic events such as ischemic stroke (IS) and transient ischemic attack (TIA) among patients with cryptogenic stroke (CS) has been the subject …
Secondary stroke prevention focuses on managing vascular risk factors such as hypertension, hyperglycemia, and dyslipidemia. However, the impact of exercise training regimens (ETR) on these factors post-stroke remains unclear. We conducted a …
Despite advances in reperfusion therapies following cerebral ischemic stroke, effective treatment options remain limited, and achieving optimal outcomes post-revascularization continues to be a significant challenge. Increasing evidences have …
Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
New MRI contrast agents are reshaping diagnostic imaging, promising lower gadolinium exposure amid evolving practice guidelines. How can you optimize contrast selection, dosing, and patient care in this rapidly advancing field?
This content is intended for healthcare professionals outside of the UK.
Stroke is one of the major causes of disability-adjusted life years worldwide and the second most common cause of death in Europe [ 1 ]. In approximately 10% of all strokes, no other evident cause is identified except a patent foramen ovale (PFO) [ …2
Cognitive impairment resulting from cerebellar damage, known as cerebellar cognitive affective syndrome (CCAS), can cause language impairment and aphasia. The disruption of the cerebro-cerebellar pathway is a possible mechanism for CCAS.
Delayed cerebral ischemia (DCI) affects approximately 30% of aneurysmal subarachnoid hemorrhage (aSAH) survivors and is a leading cause of morbidity and mortality post-aSAH. Current risk assessment relies on radiographic severity scores that …
The Alberta Stroke Programme Early Computed Tomography Score (ASPECTS) is a widely used, rapid, and practical score for quantifying the extent of early ischemic changes in acute ischemic stroke [ 1 , 2 ]. Several studies showed that ASPECTS is …