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Journal of Cancer Research and Clinical Oncology

Issue 3/2021

Content (28 Articles)

Metastasis Review – Cancer Research

Emerging role of exosomes and exosomal microRNA in cancer: pathophysiology and clinical potential

Mohamed Ibrahim Elewaily, Alyaa R. Elsergany

Open Access Laparotomy Original Article – Cancer Research

Sentinel lymph node mapping with indocyanine green in cervical cancer patients undergoing open radical hysterectomy: a single-institution series

Nicolò Bizzarri, Pedone Anchora Luigi, Gabriella Ferrandina, Gian Franco Zannoni, Maria Vittoria Carbone, Camilla Fedele, Elena Teodorico, Valerio Gallotta, Salvatore Gueli Alletti, Vito Chiantera, Anna Fagotti, Giovanni Scambia, Francesco Fanfani

Radiotherapy Original Article – Cancer Research

Hypofractionated sequential radiotherapy boost: a promising strategy in inoperable locally advanced pancreatic cancer patients

Gian Carlo Mattiucci, Luca Boldrini, Alessia Nardangeli, Andrea D’Aviero, Milly Buwenge, Francesco Cellini, Francesco Deodato, Nicola Dinapoli, Vincenzo Frascino, Gabriella Macchia, Alessio Giuseppe Morganti, Vincenzo Valentini

Radiotherapy Correction

Correction to: Hypofractionated sequential radiotherapy boost: a promising strategy in inoperable locally advanced pancreatic cancer patients

Gian Carlo Mattiucci, Luca Boldrini, Alessia Nardangeli, Andrea D’Aviero, Milly Buwenge, Francesco Cellini, Francesco Deodato, Nicola Dinapoli, Vincenzo Frascino, Gabriella Macchia, Alessio Giuseppe Morganti, Vincenzo Valentini

Open Access NSCLC Original Article – Cancer Research

Treatment patterns and clinical outcomes in patients with advanced non-small cell lung cancer initiating first-line treatment in the US community oncology setting: a real-world retrospective observational study

Eric Nadler, Bhakti Arondekar, Kathleen Marie Aguilar, Jie Zhou, Jane Chang, Xinke Zhang, Vivek Pawar

Diffuse Large B-Cell Lymphoma Original Article – Cancer Research

Vincristine upregulates PD-L1 and increases the efficacy of PD-L1 blockade therapy in diffuse large B-cell lymphoma

Ting Wei, Manjun Li, Zhigang Zhu, Huabao Xiong, Han Shen, Hui Zhang, Qinghua Du, Qingshan Li

Epstein-Barr Virus Original Article – Cancer Research

Genetic variants in NKG2D axis and susceptibility to Epstein–Barr virus-induced nasopharyngeal carcinoma

Nguyen Hoang Viet, Nguyen Quang Trung, Le Thanh Dong, Ly Quoc Trung, J. Luis Espinoza

NSCLC Original Article – Cancer Research

Impact of STAT1 polymorphisms on crizotinib-induced hepatotoxicity in ALK-positive non-small cell lung cancer patients

Shuang Xin, Wenfeng Fang, Jianwen Li, Delan Li, Changzheng Wang, Quanfei Huang, Min Huang, Wei Zhuang, Xueding Wang, Likun Chen

NSCLC Original Article – Cancer Research

Combination of CD47 and CD68 expression predicts survival in eastern-Asian patients with non-small cell lung cancer

Fangqiu Fu, Yang Zhang, Zhendong Gao, Yue Zhao, Zhexu Wen, Han Han, Yuan Li, Hong Hu, Haiquan Chen

Open Access Ultrasound Original Article – Cancer Research

Discrepancies between radiological and histological findings in preoperative core needle (CNB) and vacuum-assisted (VAB) breast biopsies

Inna Jörg, Jann Wieler, Constanze Elfgen, Kristina Bolten, Claudia Hutzli, Julia Talimi, Denise Vorburger, Matthias Choschzick, Linda Moskovszky, Konstantin Dedes, Zsuzsanna Varga

Open Access Original Article – Cancer Research

Transcription factors CP2 and YY1 as prognostic markers in head and neck squamous cell carcinoma: analysis of The Cancer Genome Atlas and a second independent cohort

Julia Schnoell, Bernhard J. Jank, Lorenz Kadletz-Wanke, Stefan Stoiber, Clemens P. Spielvogel, Elisabeth Gurnhofer, Lukas Kenner, Gregor Heiduschka

Melanoma Original Article – Cancer Research

Downregulation of lncRNA TSLNC8 promotes melanoma resistance to BRAF inhibitor PLX4720 through binding with PP1α to re-activate MAPK signaling

Yongzhi Han, Jing Fang, Zhiwei Xiao, Jian Deng, Minghui Zhang, Lixiong Gu

Open Access Glioblastoma Original Article – Cancer Research

Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent

Bodo Haas, Janine Ciftcioglu, Sanja Jermar, Sandra Weickhardt, Niels Eckstein, Bernd Kaina

Radiotherapy Review – Clinical Oncology

Post-operative management of brain metastases: GRADE-based clinical practice recommendations on behalf of the Italian Association of Radiotherapy and Clinical Oncology (AIRO)

Chiara Reverberi, Stefania Volpe, Damiano Balestrini, Michela Buglione, Piera Navarria, Silvia Scoccianti, Pierpaolo Panciani, Marco Krengli, Luigi Pirtoli, Lorenzo Bordi, Giovanni L. Pappagallo, Rolando M. D.’ Angelillo, Stefano M. Magrini, Stefano Arcangeli

Metastasis Original Article – Clinical Oncology

Risk stratification of postoperative recurrence in hypopharyngeal squamous-cell carcinoma patients with nodal metastasis

Hanqing Lin, Tian Wang, Yu Heng, Xiaoke Zhu, Liang Zhou, Ming Zhang, Yong Shi, Pengyu Cao, Lei Tao

Radiotherapy Original Article – Clinical Oncology

Patterns of failure after adjuvant “sandwich” chemo-radio-chemotherapy in locally advanced (stage III–IVA) endometrial cancer

Francesco Raspagliesi, Giorgio Bogani, Ciro Pinelli, Jvan Casarin, Anna Maria Cerrotta, Clelia Teresa Delle Curti, Antonino Ditto, Valentina Chiappa, Sara Bosio, Francesca Bertolina, Giuseppe Sarpietro, Andrea Dell’Acqua, Violante Di Donato, Fabio Ghezzi

Open Access Hepatocellular Carcinoma Original Article – Clinical Oncology

Preoperative identification of microvascular invasion in hepatocellular carcinoma by XGBoost and deep learning

Yi-Quan Jiang, Su-E Cao, Shilei Cao, Jian-Ning Chen, Guo-Ying Wang, Wen-Qi Shi, Yi-Nan Deng, Na Cheng, Kai Ma, Kai-Ning Zeng, Xi-Jing Yan, Hao-Zhen Yang, Wen-Jing Huan, Wei-Min Tang, Yefeng Zheng, Chun-Kui Shao, Jin Wang, Yang Yang, Gui-Hua Chen

Metastasis Original Article – Clinical Oncology

Clinical effectiveness of percutaneous vertebroplasty in conjunction with postoperative radiotherapy in the treatment of spinal metastases

Miaoman Lin, Mingjia Qu, Wei Huang, Tao Liu, Ruimeng Duan, Yashuai Yuan, Junxiao Gao, Meng Zhang, Xiaobing Yu

Open Access Endometrial Cancer Original Article – Clinical Oncology

Role of minimally invasive surgery versus open approach in patients with early-stage uterine carcinosarcomas: a retrospective multicentric study

Giacomo Corrado, Francesca Ciccarone, Francesco Cosentino, Francesco Legge, Andrea Rosati, Martina Arcieri, Luigi Carlo Turco, Camilla Certelli, Alex Federico, Enrico Vizza, Francesco Fanfani, Giovanni Scambia, Gabriella Ferrandina

Brachytherapy Original Article – Clinical Oncology

Brachytherapy vs external beam therapy among NSCLC patients undergoing limited surgical resection

Mausam A. Patel, Yama Fazli, Sowmya Sivakumar, Coleman Dennis, Sanjay Maraboyina, Arpan V. Prabhu, Thomas Kim

Lymphoma Original Article – Clinical Oncology

Using etoposide + dexamethasone-based regimens to treat nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis

Liqiang Wei, Lei Yang, Jia Cong, Jin Ye, Xin Li, Na Yao, Jing Yang, Jing Ding, Jingwen Wang

Breast Cancer Original Article – Clinical Oncology

Multigene panel testing for hereditary breast and ovarian cancer in the province of Ontario

Jordan Lerner-Ellis, Chloe Mighton, Conxi Lazaro, Nicholas Watkins, Vanessa Di Gioacchino, Andrew Wong, Martin C. Chang, George S. Charames

Bevacizumab Original Article – Clinical Oncology

Anti-PD-1/L1 plus anti-angiogenesis therapy as second-line or later treatment in advanced lung adenocarcinoma

Di Huang, Pengfei Cui, Ziwei Huang, Zhaozhen Wu, Haitao Tao, Sujie Zhang, Rong Xiang, Yi Hu

Glioblastoma Original Article – Clinical Oncology

Association between temporal muscle thickness and clinical outcomes in patients with newly diagnosed glioblastoma

Geon An, Stephen Ahn, Jae-Sung Park, Sin- Soo Jeun, Yong- Kil Hong

Salpingectomy Original Article – Clinical Oncology

Increase of fallopian tube and decrease of ovarian carcinoma: fact or fake?

Anne Kathrin Höhn, Sabine Klagges, Albrecht Gläser, Sabine Taubenheim, Nadja Dornhöfer, Jens Einenkel, Grit Gesine Ruth Hiller, Christine E. Brambs, Lars-Christian Horn

Hepatocellular Carcinoma Original Article – Clinical Oncology

Stereotactic body radiotherapy in hepatocellular carcinoma: patient selection and predictors of outcome and toxicity

Mauro Loi, Tiziana Comito, Ciro Franzese, Luca Dominici, Lorenzo Lo Faro, Elena Clerici, Davide Franceschini, Pietro Mancosu, Giacomo Reggiori, Pasqualina Gallo, Marco Badalamenti, Marta Scorsetti

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.