Issue 1/2011
Content (27 Articles)
Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42
Martin Ruehl, Marion Muche, Christian Freise, Ulrike Erben, Ulf Neumann, Detlef Schuppan, Yury Popov, Walburga Dieterich, Martin Zeitz, Richard W Farndale, Rajan Somasundaram
The role of fibrocytes in fibrotic diseases of the lungs and heart
Ellen C Keeley, Borna Mehrad, Robert M Strieter
Hyaluronidase recruits mesenchymal-like cells to the lung and ameliorates fibrosis
Claudia S Bitencourt, Priscilla AT Pereira, Simone G Ramos, Suely V Sampaio, Eliane C Arantes, David M Aronoff, Lúcia H Faccioli
Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling
Elvira Olaso, Hsin-Chieh Lin, Li-Hsien Wang, Scott L Friedman
Centrilobular emphysema combined with pulmonary fibrosis results in improved survival
Nevins W Todd, Jean Jeudy, Sachin Lavania, Teri J Franks, Jeffrey R Galvin, Janaki Deepak, Edward J Britt, Sergei P Atamas
Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts
Silvia Smaldone, Jacopo Olivieri, Gabriele Luca Gusella, Gianluca Moroncini, Armando Gabrielli, Francesco Ramirez
Thrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism
Yunliang Chen, Andrew Leask, David J Abraham, Laura Kennedy, Xu Shi-wen, Christopher P Denton, Carol M Black, Liaquat S Verjee, Mark Eastwood
Immune response CC chemokines CCL2 and CCL5 are associated with pulmonary sarcoidosis
Vyacheslav Palchevskiy, Nastran Hashemi, Stephen S Weigt, Ying Ying Xue, Ariss Derhovanessian, Michael P Keane, Robert M Strieter, Michael C Fishbein, Jane C Deng, Joseph P Lynch III, Robert Elashoff, John A Belperio
Epithelial to mesenchymal transition as a biomarker in renal fibrosis: are we ready for the bedside?
Pierre Galichon, Alexandre Hertig
Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis
Xueyan Peng, Susan K Mathai, Lynne A Murray, Thomas Russell, Ronald Reilkoff, Qingsheng Chen, Mridu Gulati, Jack A Elias, Richard Bucala, Ye Gan, Erica L Herzog
Thrombospondin 1 in hypoxia-conditioned media blocks the growth of human microvascular endothelial cells and is increased in systemic sclerosis tissues
Luke Morgan-Rowe, Joanna Nikitorowicz, Xu Shiwen, Andrew Leask, Janice Tsui, David Abraham, Richard Stratton
Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts
Carola Krause, Peter Kloen, Peter ten Dijke
Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide
Elena Tourkina, Michael Bonner, James Oates, Ann Hofbauer, Mathieu Richard, Sergei Znoyko, Richard P Visconti, Jing Zhang, Corey M Hatfield, Richard M Silver, Stanley Hoffman
Centrilobular emphysema combined with pulmonary fibrosis results in improved survival: a response
Vincent Cottin, Jean-François Cordier, Athol U Wells
Survival in pulmonary fibrosis combined with emphysema: likely defined by characteristics of specific patient subpopulations
Nevins W Todd, Sergei P Atamas
TLR9-induced interferon β is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis
Tracy R Luckhardt, Stephanie M Coomes, Glenda Trujillo, Joshua S Stoolman, Kevin M Vannella, Urvashi Bhan, Carol A Wilke, Thomas A Moore, Galen B Toews, Cory Hogaboam, Bethany B Moore
Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis
Toni Segovia-Silvestre, Vedrana Reichenbach, Guillermo Fernández-Varo, Efstathios Vassiliadis, Natasha Barascuk, Manuel Morales-Ruiz, Morten A Karsdal, Wladimiro Jiménez
Mesenchymal stem cells: from experiment to clinic
William R Otto, Nicholas A Wright
Plasma and cellular fibronectin: distinct and independent functions during tissue repair
Wing S To, Kim S Midwood
Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis
Sanne S Veidal, Morten A Karsdal, Arkadiusz Nawrocki, Martin R Larsen, Yueqin Dai, Qinlong Zheng, Per Hägglund, Ben Vainer, Helene Skjøt-Arkil, Diana J Leeming
Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes
Jason E Ekert, Lynne A Murray, Anuk M Das, Hai Sheng, Jill Giles-Komar, Michael A Rycyzyn
A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation
Elisabeth A Kastelijn, Coline HM van Moorsel, Karin M Kazemier, Suzan M Roothaan, Henk JT Ruven, Johanna M Kwakkel-van Erp, Ed A van de Graaf, Pieter Zanen, Diana A van Kessel, Jan C Grutters
Cooperative interaction of CTGF and TGF-β in animal models of fibrotic disease
Qingjian Wang, William Usinger, Blake Nichols, Julia Gray, Leon Xu, Todd W Seeley, Mitch Brenner, Guangjie Guo, Weihua Zhang, Noelynn Oliver, Al Lin, David Yeowell
Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors
Megumi Kanasaki, Takako Nagai, Munehiro Kitada, Daisuke Koya, Keizo Kanasaki
Animal models for investigating chronic pancreatitis
Alexander A Aghdassi, Julia Mayerle, Sandra Christochowitz, Frank U Weiss, Matthias Sendler, Markus M Lerch
What is new in the liver sinusoids? meeting report, 16th International Symposium on Cells of the Hepatic Sinusoid (ISCHS)
Krista Rombouts, Massimo Pinzani
A phage-targeting strategy for the design of spatiotemporal drug delivery from grafted matrices
Ritsuko Sawada, Carrie Y Peterson, Ana Maria Gonzalez, Bruce M Potenza, Barbara Mueller, Raul Coimbra, Brian P Eliceiri, Andrew Baird