Diabetologia

Up Front

Social networks and type 2 diabetes: a narrative review

Miranda T. Schram, Willem J. J. Assendelft, Theo G. van Tilburg, Nicole H. T. M. Dukers-Muijrers

HDL and type 2 diabetes: the chicken or the egg?

Eva Xepapadaki, Ioanna Nikdima, Eleftheria C. Sagiadinou, Evangelia Zvintzou, Kyriakos E. Kypreos

Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes Remission Clinical Trial (DiRECT)

Wilma S. Leslie, Eman Ali, Leanne Harris, C. Martina Messow, Naomi T. Brosnahan, George Thom, E. Louise McCombie, Alison C. Barnes, Naveed Sattar, Roy Taylor, Michael E. J. Lean

Potentially modifiable risk factors of preterm delivery in women with type 1 and type 2 diabetes

Julie C. Søholm, Marianne Vestgaard, Björg Ásbjörnsdóttir, Nicoline C. Do, Berit W. Pedersen, Lone Storgaard, Birgitte B. Nielsen, Lene Ringholm, Peter Damm, Elisabeth R. Mathiesen

Major adverse cardiovascular and limb events in patients with diabetes treated with GLP-1 receptor agonists vs DPP-4 inhibitors

Donna Shu-Han Lin, Jen-Kuang Lee, Wen-Jone Chen

Are people with metabolically healthy obesity really healthy? A prospective cohort study of 381,363 UK Biobank participants

Ziyi Zhou, John Macpherson, Stuart R. Gray, Jason M. R. Gill, Paul Welsh, Carlos Celis-Morales, Naveed Sattar, Jill P. Pell, Frederick K. Ho

Comparison between data-driven clusters and models based on clinical features to predict outcomes in type 2 diabetes: nationwide observational study

Moa Lugner, Soffia Gudbjörnsdottir, Naveed Sattar, Ann-Marie Svensson, Mervete Miftaraj, Katarina Eeg-Olofsson, Björn Eliasson, Stefan Franzén

Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study

Roderick C. Slieker, Louise A. Donnelly, Hugo Fitipaldi, Gerard A. Bouland, Giuseppe N. Giordano, Mikael Åkerlund, Mathias J. Gerl, Emma Ahlqvist, Ashfaq Ali, Iulian Dragan, Andreas Festa, Michael K. Hansen, Dina Mansour Aly, Min Kim, Dmitry Kuznetsov, Florence Mehl, Christian Klose, Kai Simons, Imre Pavo, Timothy J. Pullen, Tommi Suvitaival, Asger Wretlind, Peter Rossing, Valeriya Lyssenko, Cristina Legido-Quigley, Leif Groop, Bernard Thorens, Paul W. Franks, Mark Ibberson, Guy A. Rutter, Joline W. J. Beulens, Leen M. ‘t Hart, Ewan R. Pearson

Young age at diabetes diagnosis amplifies the effect of diabetes duration on risk of chronic kidney disease: a prospective cohort study

Hongjiang Wu, Eric S. H. Lau, Aimin Yang, Baoqi Fan, Ronald C. W. Ma, Alice P. S. Kong, Elaine Chow, Wing-Yee So, Juliana C. N. Chan, Andrea O. Y. Luk

Development and validation of a cardiovascular risk prediction model in type 1 diabetes

Stuart J. McGurnaghan, Paul M. McKeigue, Stephanie H. Read, Stefan Franzen, Ann-Marie Svensson, Marco Colombo, Shona Livingstone, Bassam Farran, Thomas M. Caparrotta, Luke A. K. Blackbourn, Joseph Mellor, Ioanna Thoma, Naveed Sattar, Sarah H. Wild, Soffia Gudbjörnsdottir, Helen M. Colhoun

Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control

Johanne Tremblay, Mounsif Haloui, Redha Attaoua, Ramzan Tahir, Camil Hishmih, François Harvey, François-Christophe Marois-Blanchet, Carole Long, Paul Simon, Lara Santucci, Candan Hizel, John Chalmers, Michel Marre, Stephen Harrap, Renata Cífková, Alena Krajčoviechová, David R. Matthews, Bryan Williams, Neil Poulter, Sophia Zoungas, Stephen Colagiuri, Giuseppe Mancia, Diederick E. Grobbee, Anthony Rodgers, Liusheng Liu, Mawussé Agbessi, Vanessa Bruat, Marie-Julie Favé, Michelle P. Harwood, Philip Awadalla, Mark Woodward, Julie G. Hussin, Pavel Hamet

HLA class I genes modulate disease risk and age at onset together with DR-DQ in Chinese patients with insulin-requiring type 1 diabetes

Ziyu Jiang, Wenqian Ren, Hua Liang, Jinhua Yan, Daizhi Yang, Sihui Luo, Xueying Zheng, Guo-Wang Lin, Yingxin Xian, Wen Xu, Bin Yao, Janelle A. Noble, Jin-Xin Bei, Leif Groop, Jianping Weng

M1 macrophage-derived exosomes impair beta cell insulin secretion via miR-212-5p by targeting SIRT2 and inhibiting Akt/GSK-3β/β-catenin pathway in mice

Bin Qian, Yang Yang, Ningyuan Tang, Jiahui Wang, Peng Sun, Nan Yang, Fang Chen, Tijun Wu, Tong Sun, Yating Li, Xiaoai Chang, Yunxia Zhu, Yaqin Zhang, Xiao Han

Improving clinical utility of GAD65 autoantibodies by electrochemiluminescence assay and clinical phenotype when identifying autoimmune adult-onset diabetes

Yong Gu, Xiaofan Jia, Tanwi Vartak, Dongmei Miao, Fran Dong, Samuel T. Jerram, Marian Rewers, Assiamira Ferrara, Jean M. Lawrence, Liping Yu, R. David Leslie, Richard David Leslie, Mohammed I Hawa, Paolo Pozzilli, Henning Beck-Nielsen, Knud Yderstraede, Steven Hunter, David Hadden, Raffaella Buzzetti, Werner Scherbaum, Hubert Kolb, Nanette C. Schloot, Jochen Seissler, Guntram Schernthaner, Jaakko Tuomilehto, Cinzia Sarti, Alberto De Leiva, Eulalia Brugues, Didac Mauricio, Charles Thivolet, Jean M Lawrence, Assiamira Ferrara, Jeff M. Slezak, Charles Quesenberry, Sharon Saydah, Liping Yu, Marian Rewers

The effect of morning vs evening exercise training on glycaemic control and serum metabolites in overweight/obese men: a randomised trial

Trine Moholdt, Evelyn B. Parr, Brooke L. Devlin, Julia Debik, Guro Giskeødegård, John A. Hawley

Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes

Rasmus J. O. Sjögren, David Rizo-Roca, Alexander V. Chibalin, Elin Chorell, Regula Furrer, Shintaro Katayama, Jun Harada, Håkan K. R. Karlsson, Christoph Handschin, Thomas Moritz, Anna Krook, Erik Näslund, Juleen R. Zierath

Non-alcoholic fatty liver disease in mice with hepatocyte-specific deletion of mitochondrial fission factor

Yukina Takeichi, Takashi Miyazawa, Shohei Sakamoto, Yuki Hanada, Lixiang Wang, Kazuhito Gotoh, Keiichiro Uchida, Shunsuke Katsuhara, Ryuichi Sakamoto, Takaya Ishihara, Keiji Masuda, Naotada Ishihara, Masatoshi Nomura, Yoshihiro Ogawa

AT2R deficiency in mice accelerates podocyte dysfunction in diabetic progeny in a sex-dependent manner

Min-Chun Liao, Yu-Chao Pang, Shiao-Ying Chang, Xin-Ping Zhao, Isabelle Chenier, Julie R. Ingelfinger, John S. D. Chan, Shao-Ling Zhang

Donor insulin use during stay in the intensive care unit should not preclude pancreas transplantation

Pedro Ventura-Aguiar, Enrique Montagud-Marrahi, Antonio J. Amor, Fritz Diekmann

Donor insulin use during stay in the intensive care unit should not preclude pancreas transplantation. Reply to Ventura-Aguiar P, Montagud-Marrahi E, Amor AJ et al [letter]

Iestyn M. Shapey, Angela Summers, Hussein Khambalia, Petros Yiannoullou, Catherine Fullwood, Neil A. Hanley, Titus Augustine, Martin K. Rutter, David van Dellen