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Advances in Therapy

Issue 5/2019

Content (22 Articles)

Open Access Commentary

The Case for the Use of Patient and Caregiver Perception of Change Assessments in Rare Disease Clinical Trials: A Methodologic Overview

Marielle G. Contesse, James E. Valentine, Tracy E. Wall, Mindy G. Leffler

Open Access Insulin Glargine Review

Differentiating Basal Insulin Preparations: Understanding How They Work Explains Why They Are Different

Alice Y. Y. Cheng, Dhiren K. Patel, Timothy S. Reid, Kathleen Wyne

Open Access Irritable Bowel Syndrome Review

Bloating and Abdominal Distension: Clinical Approach and Management

Amir Mari, Fadi Abu Backer, Mahmud Mahamid, Hana Amara, Dan Carter, Doron Boltin, Ram Dickman

Open Access Systemic Sclerosis Original Research

Economic Burden of Illness Among Commercially Insured Patients with Systemic Sclerosis with Interstitial Lung Disease in the USA: A Claims Data Analysis

Zhou Zhou, Yanni Fan, Darren Thomason, Wenxi Tang, Xinyue Liu, Zheng-Yi Zhou, Dendy Macaulay, Aryeh Fischer

NSCLC Original Research

Cost-Effectiveness of Alectinib for Patients with Untreated ALK-Positive Non-Small Cell Lung Cancer in China

Haijing Guan, Yanan Sheng, Wanjie Guo, Sheng Han, Luwen Shi

Open Access Pharmacokinetics Original Research

Maximum Tolerated Dose and Pharmacokinetics of Paclitaxel Micellar in Patients with Recurrent Malignant Solid Tumours: A Dose-Escalation Study

Olof Borgå, Roger Henriksson, Helena Bjermo, Elsa Lilienberg, Nina Heldring, Niklas Loman

Open Access Spinal Muscular Atrophy Original Research

Survival, Motor Function, and Motor Milestones: Comparison of AVXS-101 Relative to Nusinersen for the Treatment of Infants with Spinal Muscular Atrophy Type 1

Omar Dabbous, Benit Maru, Jeroen P. Jansen, Maria Lorenzi, Martin Cloutier, Annie Guérin, Irina Pivneva, Eric Q. Wu, Ramesh Arjunji, Douglas Feltner, Douglas M. Sproule

Pompe Disease Original Research

Assessing the Role of Anti rh-GAA in Modulating Response to ERT in a Late-Onset Pompe Disease Cohort from the Italian GSDII Study Group

Massimiliano Filosto, Stefano Cotti Piccinelli, Sabrina Ravaglia, Serenella Servidei, Maurizio Moggio, Olimpia Musumeci, Maria Alice Donati, Elena Pegoraro, Antonio Di Muzio, Lorenzo Maggi, Paola Tonin, Gianni Marrosu, Cristina Sancricca, Alberto Lerario, Michele Sacchini, Claudio Semplicini, Virginia Bozzoni, Roberta Telese, Silvia Bonanno, Rachele Piras, Maria Antonietta Maioli, Giulia Ricci, Liliana Vercelli, Anna Galvagni, Serena Gallo Cassarino, Filomena Caria, Tiziana Mongini, Gabriele Siciliano, Alessandro Padovani, Antonio Toscano

Open Access Insulins Original Research

Switching “Real-World” Diabetes Patients to Degludec from Other Basal Insulins Provides Different Clinical Benefits According to Their Baseline Glycemic Control

Nikolaos Tentolouris, Søren T. Knudsen, Annunziata Lapolla, Michael Lyng Wolden, Steffen Haldrup, Bernd Schultes

Ovarian Cancer Original Research

Thyroid Cancer Benefits the Prognosis of Ovarian Cancer: A SEER-Based Study

Qiong Yang, Zhiyong Wu, Xujun He, Leibo Yu, Xiaofei Zhang, Kefeng Lei

Long-Term Effects and Adverse Events of Nintedanib Therapy in Idiopathic Pulmonary Fibrosis Patients with Functionally Advanced Disease

Eniko Barczi, Livia Starobinski, Abigel Kolonics-Farkas, Noemi Eszes, Aniko Bohacs, Martina Vasakova, Karel Hejduk, Veronika Müller

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.