Issue 1/2010
Content (184 Articles)
Collagen V-induced nasal tolerance downregulates pulmonary collagen mRNA gene and TGF-beta expression in experimental systemic sclerosis
Ana Paula P Velosa, Walcy R Teodoro, Daniel M dos Anjos, Renata Konno, Cristiane C Oliveira, Maria LH Katayama, Edwin R Parra, Vera L Capelozzi, Natalino H Yoshinari
Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes
Esmeralda Juarez, Carlos Nuñez, Eduardo Sada, Jerrold J Ellner, Stephan K Schwander, Martha Torres
Changes in oxygen partial pressure of brain tissue in an animal model of obstructive apnea
Isaac Almendros, Josep M Montserrat, Marta Torres, Constancio González, Daniel Navajas, Ramon Farré
Potential mechanisms underlying the acute lung dysfunction and bacterial extrapulmonary dissemination during Burkholderia cenocepacia respiratory infection
Luiz G Cunha Jr, Maria-Cristina Assis, Gloria-Beatriz Machado, Ana P Assef, Elizabeth A Marques, Robson S Leão, Alessandra M Saliba, Maria-Cristina Plotkowski
Increase in markers of airway inflammation after ozone exposure can be observed also in stable treated asthmatics with minimal functional response to ozone
Barbara Vagaggini, Maria Laura E Bartoli, Silvana Cianchetti, Francesco Costa, Elena Bacci, Federico L Dente, Antonella Di Franco, Laura Malagrinò, Pierluigi Paggiaro
Long acting β2-agonist and corticosteroid restore airway glandular cell function altered by bacterial supernatant
Jean-Marie Zahm, Franck Delavoie, Férial Toumi, Béatrice Nawrocki-Raby, Claire Kileztky, Jean Michel, Gérard Balossier, Malcolm Johnson, Christelle Coraux, Philippe Birembaut
Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation
Tania Maes, Sharen Provoost, Ellen A Lanckacker, Didier D Cataldo, Jeroen AJ Vanoirbeek, Benoit Nemery, Kurt G Tournoy, Guy F Joos
Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One
M Innes Asher, Alistair W Stewart, Javier Mallol, Stephen Montefort, Christopher KW Lai, Nadia Aït-Khaled, Joseph Odhiambo
Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography
Peter B Noble, Robert A McLaughlin, Adrian R West, Sven Becker, Julian J Armstrong, Peter K McFawn, Peter R Eastwood, David R Hillman, David D Sampson, Howard W Mitchell
Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial
Sanjay Sethi, Paul W Jones, Marlize Schmitt Theron, Marc Miravitlles, Ethan Rubinstein, Jadwiga A Wedzicha, Robert Wilson
Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among children in Taiwan
Ching-Hui Tsai, Jiun-Hau Huang, Bing-Fang Hwang, Yungling L Lee
Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis
Christopher J Ryerson, Shalini Nayar, John R Swiston, Don D Sin
Nicotine enhances murine airway contractile responses to kinin receptor agonists via activation of JNK- and PDE4-related intracellular pathways
Yuan Xu, Yaping Zhang, Lars-Olaf Cardell
Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice
Jessica S Siegle, Nicole Hansbro, Cristan Herbert, Helene F Rosenberg, Joseph B Domachowske, Kelly L Asquith, Paul S Foster, Rakesh K Kumar
Abdominal muscle fatigue following exercise in chronic obstructive pulmonary disease
Nicholas S Hopkinson, Mark J Dayer, John Moxham, Michael I Polkey
Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis
Shin-Hwa Lee, An-Soo Jang, Young-Eun Kim, Ji-Yeon Cha, Tae-Hoon Kim, Seok Jung, Seong-Kyu Park, You-Kyoung Lee, Jong-Ho Won, Yong-Hoon Kim, Choon-Sik Park
Effects of a dual CCR3 and H1-antagonist on symptoms and eosinophilic inflammation in allergic rhinitis
Lennart Greiff, Cecilia Ahlström-Emanuelsson, Ash Bahl, Thomas Bengtsson, Kerstin Dahlström, Jonas Erjefält, Henrik Widegren, Morgan Andersson
Identification of lung cancer with high sensitivity and specificity by blood testing
Petra Leidinger, Andreas Keller, Sabrina Heisel, Nicole Ludwig, Stefanie Rheinheimer, Veronika Klein, Claudia Andres, Andrea Staratschek-Jox, Jürgen Wolf, Erich Stoelben, Bernhard Stephan, Ingo Stehle, Jürg Hamacher, Hanno Huwer, Hans-Peter Lenhof, Eckart Meese
Effects of Liver × receptor agonist treatment on signal transduction pathways in acute lung inflammation
Concetta Crisafulli, Emanuela Mazzon, Irene Paterniti, Maria Galuppo, Placido Bramanti, Salvatore Cuzzocrea
Respiratory syncytial virus infection reduces lung inflammation and fibrosis in mice exposed to vanadium pentoxide
Elizabeth A Turpin, Aurita Antao-Menezes, Mark F Cesta, James B Mangum, Duncan G Wallace, Edilberto Bermudez, James C Bonner
Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells
Xiahui Tan, Hayat Dagher, Craig A Hutton, Jane E Bourke
Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease
Erik P Riesenfeld, Michael J Sullivan, John A Thompson-Figueroa, Hans C Haverkamp, Lennart K Lundblad, Jason HT Bates, Charles G Irvin
MMP-9 gene variants increase the risk for non-atopic asthma in children
Leonardo A Pinto, Martin Depner, Norman Klopp, Thomas Illig, Christian Vogelberg, Erika von Mutius, Michael Kabesch
Transcriptional profiling of the acute pulmonary inflammatory response induced by LPS: role of neutrophils
Nejla Güngör, Jeroen LA Pennings, Ad M Knaapen, Roland K Chiu, Marco Peluso, Roger WL Godschalk, Frederik J Van Schooten
Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients
Johan Grunewald, Boel Brynedal, Pernilla Darlington, Magnus Nisell, Kerstin Cederlund, Jan Hillert, Anders Eklund
The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma
Dave Singh, Frank Petavy, Alex J Macdonald, Aili L Lazaar, Brian J O'Connor
Mechanical ventilation modulates TLR4 and IRAK-3 in a non-infectious, ventilator-induced lung injury model
Jesús Villar, Nuria E Cabrera, Milena Casula, Carlos Flores, Francisco Valladares, Lucio Díaz-Flores, Mercedes Muros, Arthur S Slutsky, Robert M Kacmarek
Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function
Wendy A Neveu, Jenna L Allard, Danielle M Raymond, Lorraine M Bourassa, Stephanie M Burns, Janice Y Bunn, Charles G Irvin, David A Kaminsky, Mercedes Rincon
Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study
Nicholas D Giardino, Jeffrey L Curtis, Adin-Cristian Andrei, Vincent S Fan, Joshua O Benditt, Mark Lyubkin, Keith Naunheim, Gerard Criner, Barry Make, Robert A Wise, Susan K Murray, Alfred P Fishman, Frank C Sciurba, Israel Liberzon, Fernando J Martinez
Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation
Michael H Cho, George R Washko, Thomas J Hoffmann, Gerard J Criner, Eric A Hoffman, Fernando J Martinez, Nan Laird, John J Reilly, Edwin K Silverman
Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance
Norihiro Kikuchi, Yukio Ishii, Yuko Morishima, Yuichi Yageta, Norihiro Haraguchi, Ken Itoh, Masayuki Yamamoto, Nobuyuki Hizawa
Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases
Veronica Marcos, Phillip Latzin, Andreas Hector, Sebastian Sonanini, Florian Hoffmann, Martin Lacher, Barbara Koller, Philip Bufler, Thomas Nicolai, Dominik Hartl, Matthias Griese
Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice
Yun-Feng Ni, Jian Wang, Xiao-Long Yan, Feng Tian, Jin-Bo Zhao, Yun-Jie Wang, Tao Jiang
A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice
Yuanjue Zhu, Yong Liu, Weixun Zhou, Ruolan Xiang, Lei Jiang, Kewu Huang, Yu Xiao, Zijian Guo, Jinming Gao
Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD
Geert R Van Pottelberge, Ken R Bracke, Ingel K Demedts, Kim De Rijck, Susanne M Reinartz, Cornelis M van Drunen, Geert M Verleden, Frank E Vermassen, Guy F Joos, Guy G Brusselle
Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters
Tao Wang, Su-Xia Han, Shang-Fu Zhang, Yun-Ye Ning, Lei Chen, Ya-Juan Chen, Guang-Ming He, Dan Xu, Jin An, Ting Yang, Xiao-Hong Zhang, Fu-Qiang Wen
Iron deposition and increased alveolar septal capillary density in nonfibrotic lung tissue are associated with pulmonary hypertension in idiopathic pulmonary fibrosis
Kyung-Hee Kim, Fabien Maldonado, Jay H Ryu, Patrick W Eiken, Thomas E Hartman, Brian J Bartholmai, Paul A Decker, Eunhee S Yi
Positive End-Expiratory Pressure may alter breathing cardiovascular variability and baroreflex gain in mechanically ventilated patients
Andry Van de Louw, Claire Médigue, Yves Papelier, François Cottin
Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats
Shui-Juan Zhang, Yang-Mei Deng, Yi-Liang Zhu, Xin-Wei Dong, Jun-Xia Jiang, Qiang-Min Xie
Regional differences in prediction models of lung function in Germany
Eva Schnabel, Chih-Mei Chen, Beate Koch, Stefan Karrasch, Rudolf A Jörres, Torsten Schäfer, Claus Vogelmeier, Ralf Ewert, Christoph Schäper, Henry Völzke, Anne Obst, Stephan B Felix, H-Erich Wichmann, Sven Gläser, Joachim Heinrich
Multi analyte profiling and variability of inflammatory markers in blood and induced sputum in patients with stable COPD
Shawn D Aaron, Katherine L Vandemheen, Timothy Ramsay, Chun Zhang, Zafrira Avnur, Tania Nikolcheva, Anthony Quinn
Partial pulmonary embolization disrupts alveolarization in fetal sheep
Caitlin E Filby, Stuart B Hooper, Megan J Wallace
Are exhaled nitric oxide measurements using the portable NIOX MINO repeatable?
Anna Selby, Bernie Clayton, Jane Grundy, Katy Pike, Kirsty Drew, Abid Raza, Ramesh Kurukulaaratchy, S Hasan Arshad, Graham Roberts
Survival in severe alpha-1-antitrypsin deficiency (PiZZ)
Hanan A Tanash, Peter M Nilsson, Jan-Åke Nilsson, Eeva Piitulainen
Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study
Robert Vassallo, Paula R Walters, Jeffrey Lamont, Theodore J Kottom, Eunhee S Yi, Andrew H Limper
Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients
Marianna Siganaki, Anastasios V Koutsopoulos, Eirini Neofytou, Eleni Vlachaki, Maria Psarrou, Nikolaos Soulitzis, Nikolaos Pentilas, Sophia Schiza, Nikolaos M Siafakas, Eleni G Tzortzaki
Clinical patterns in asthma based on proximal and distal airway nitric oxide categories
James L Puckett, Richard WE Taylor, Szu-Yun Leu, Olga L Guijon, Anna S Aledia, Stanley P Galant, Steven C George
Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype
Tonio Pera, Reinoud Gosens, Andries H Lesterhuis, Riham Sami, Marco van der Toorn, Johan Zaagsma, Herman Meurs
Cytosolic phospholipase A2α mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice
Yong-Zheng Wu, Mohammad Abolhassani, Mario Ollero, Fariel Dif, Naonori Uozumi, Micheline Lagranderie, Takao Shimizu, Michel Chignard, Lhousseine Touqui
Exhaled carbon monoxide in asthmatics: a meta-analysis
Jingying Zhang, Xin Yao, Rongbin Yu, Jianling Bai, Yun Sun, Mao Huang, Ian M Adcock, Peter J Barnes
Respiratory allergy to Blomia tropicalis: Immune response in four syngeneic mouse strains and assessment of a low allergen-dose, short-term experimental model
Tiana Baqueiro, Momtchilo Russo, Virgínia MG Silva, Thayna Meirelles, Pablo RS Oliveira, Eliane Gomes, Renato Barboza, Ana T Cerqueira-Lima, Camila A Figueiredo, Lain Pontes-de-Carvalho, Neuza M Alcântara-Neves
Effects of Perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells
Andreas Wemhöner, Irmgard Hackspiel, Nina Hobi, Andrea Ravasio, Thomas Haller, Mario Rüdiger
Cigarette smoking, cadmium exposure, and zinc intake on obstructive lung disorder
Yu-Sheng Lin, James L Caffrey, Man-Huei Chang, Nicole Dowling, Jou-Wei Lin
Early phase resolution of mucosal eosinophilic inflammation in allergic rhinitis
Lena Uller, Cecilia Ahlström Emanuelsson, Morgan Andersson, Jonas S Erjefält, Lennart Greiff, Carl G Persson
Altered fibroblast proteoglycan production in COPD
Oskar Hallgren, Kristian Nihlberg, Magnus Dahlbäck, Leif Bjermer, Leif T Eriksson, Jonas S Erjefält, Claes-Göran Löfdahl, Gunilla Westergren-Thorsson
The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease
Agnes Kliber, Larry D Lynd, Don D Sin
Association of circulating angiotensin converting enzyme activity with respiratory muscle function in infants
Gabriel Dimitriou, Despina Papakonstantinou, Eleana F Stavrou, Sotirios Tzifas, Aggeliki Vervenioti, Anny Onufriou, Aglaia Athanassiadou, Stefanos Mantagos
Colour of sputum is a marker for bacterial colonisation in chronic obstructive pulmonary disease
Marc Miravitlles, Alicia Marín, Eduard Monsó, Sara Vilà, Cristian de la Roza, Ramona Hervás, Cristina Esquinas, Marian García, Laura Millares, Josep Morera, Antoni Torres
Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung
Riitta Kaarteenaho, Heta Merikallio, Siri Lehtonen, Terttu Harju, Ylermi Soini
Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD
Simona E Budulac, Dirkje S Postma, Pieter S Hiemstra, Lisette IZ Kunz, Mateusz Siedlinski, Henriette A Smit, Judith M Vonk, Bea Rutgers, Wim Timens, H Marike Boezen
Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis
Danjun Fang, Richard H West, Mary E Manson, Jennifer Ruddy, Dechen Jiang, Stephen F Previs, Nitin D Sonawane, James D Burgess, Thomas J Kelley
Mucosal sensitization to German cockroach involves protease-activated receptor-2
Kristen Page, John R Ledford, Ping Zhou, Krista Dienger, Marsha Wills-Karp
Systemic inflammation in chronic obstructive pulmonary disease: a population-based study
Francisco Garcia-Rio, Marc Miravitlles, Joan B Soriano, Luis Muñoz, Enric Duran-Tauleria, Guadalupe Sánchez, Víctor Sobradillo, Julio Ancochea
Inhibition of IFN-γ-dependent antiviral airway epithelial defense by cigarette smoke
Modestos A Modestou, Lori J Manzel, Sherif El-Mahdy, Dwight C Look
K+ channel openers restore verapamil-inhibited lung fluid resolution and transepithelial ion transport
Dong-Yun Han, Hong-Guang Nie, Xiu Gu, Ramesh C Nayak, Xue-Feng Su, Jian Fu, Yongchang Chang, Vijay Rao, Hong-Long Ji
Protective effect of budesonide/formoterol compared with formoterol, salbutamol and placebo on repeated provocations with inhaled AMP in patients with asthma: a randomised, double-blind, cross-over study
René Aalbers, Martin Boorsma, Hanneke J van der Woude, René E Jonkers
The TGF-beta-Pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae
Daniel Drömann, Jan Rupp, Kristina Rohmann, Sinia Osbahr, Artur J Ulmer, Sebastian Marwitz, Kristina Röschmann, Mahdi Abdullah, Holger Schultz, Ekkehard Vollmer, Peter Zabel, Klaus Dalhoff, Torsten Goldmann
Pharmacological studies of the mechanism and function of interleukin-1β-induced miRNA-146a expression in primary human airway smooth muscle
Hanna M Larner-Svensson, Andrew E Williams, Eleni Tsitsiou, Mark M Perry, Xiaoying Jiang, Kian F Chung, Mark A Lindsay
PPARγ deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution
Dawn M Simon, Larry W Tsai, Edward P Ingenito, Barry C Starcher, Thomas J Mariani
Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice
Patti C Zeidler-Erdely, Michael L Kashon, Shengqiao Li, James M Antonini
Corticosteroid suppression of lipoxin A4 and leukotriene B4from alveolar macrophages in severe asthma
Pankaj K Bhavsar, Bruce D Levy, Mark J Hew, Michael A Pfeffer, Shamsah Kazani, Elliot Israel, Kian Fan Chung
New methodology for specific inhalation challenges with occupational agents
Simon Caron, Jean-Christian Boileau, Jean-Luc Malo, Simon Leblond
Absence of influence of gender and BMPR2 mutation type on clinical phenotypes of pulmonary arterial hypertension
Barbara Girerd, David Montani, Mélanie Eyries, Azzedine Yaici, Benjamin Sztrymf, Florence Coulet, Olivier Sitbon, Gérald Simonneau, Florent Soubrier, Marc Humbert
Weekly self-monitoring and treatment adjustment benefit patients with partly controlled and uncontrolled asthma: an analysis of the SMASHING study
Victor van der Meer, Henk F van Stel, Moira J Bakker, Albert C Roldaan, Willem JJ Assendelft, Peter J Sterk, Klaus F Rabe, Jacob K Sont
Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients
Richard A Urbanowicz, Jonathan R Lamb, Ian Todd, Jonathan M Corne, Lucy C Fairclough
Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study
Dave Singh, Lisa Edwards, Ruth Tal-Singer, Stephen Rennard
Interleukin-17 regulation: an attractive therapeutic approach for asthma
Seoung Ju Park, Yong Chul Lee
Outcome measures in chronic obstructive pulmonary disease (COPD): strengths and limitations
Thomas Glaab, Claus Vogelmeier, Roland Buhl
The role of pleiotrophin and β-catenin in fetal lung development
Tingting Weng, Lin Liu
Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction
Bakytbek Egemnazarov, Ralph T Schermuly, Bhola K Dahal, Garry T Elliott, Niel C Hoglen, Mark W Surber, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Hossein A Ghofrani
Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness
Karim H Shalaby, Leslie G Gold, Thomas F Schuessler, James G Martin, Annette Robichaud
Allergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein D
Carsten Schleh, Veit J Erpenbeck, Carla Winkler, Hans D Lauenstein, Matthias Nassimi, Armin Braun, Norbert Krug, Jens M Hohlfeld
Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length
Patricia Cmielewski, Don S Anson, David W Parsons
Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-β1 in normal human lung fibroblasts (NHLF)
Sophie Pegorier, Gaynor A Campbell, A Barry Kay, Clare M Lloyd
Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines
Jeffery M Cowden, Jason P Riley, Jing Ying Ma, Robin L Thurmond, Paul J Dunford
The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis
Kathryn A Niese, Monica G Chiaramonte, Lesley G Ellies, Marc E Rothenberg, Nives Zimmermann
Correction: Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial
Sanjay Sethi, Paul W Jones, Marlize Schmitt Theron, Marc Miravitlles, Ethan Rubinstein, Jadwiga A Wedzicha, Robert Wilson
Clinical use of biomarkers of survival in pulmonary fibrosis
Michiel Thomeer, Jan C Grutters, Wim A Wuyts, Stijn Willems, Maurits G Demedts
Azithromycin attenuates airway inflammation in a mouse model of viral bronchiolitis
Avraham Beigelman, Cassandra L Mikols, Sean P Gunsten, Carolyn L Cannon, Steven L Brody, Michael J Walter
Obstructive apneas induce early activation of mesenchymal stem cells and enhancement of endothelial wound healing
Alba Carreras, Mauricio Rojas, Theodora Tsapikouni, Josep M Montserrat, Daniel Navajas, Ramon Farré
Genetic and environmental influence on lung function impairment in Swedish twins
Jenny Hallberg, Anastasia Iliadou, Martin Anderson, Maria Gerhardsson de Verdier, Ulf Nihlén, Magnus Dahlbäck, Nancy L Pedersen, Tim Higenbottam, Magnus Svartengren
Legionella pneumophila induces human beta Defensin-3 in pulmonary cells
Stefanie Scharf, Kremena Vardarova, Friederike Lang, Bernd Schmeck, Bastian Opitz, Antje Flieger, Klaus Heuner, Stefan Hippenstiel, Norbert Suttorp, Philippe D N'Guessan
Isolation and characterization of microparticles in sputum from cystic fibrosis patients
Chiara Porro, Silvia Lepore, Teresa Trotta, Stefano Castellani, Luigi Ratclif, Anna Battaglino, Sante Di Gioia, Maria C Martínez, Massimo Conese, Angela B Maffione
Pneumocystis cell wall β-glucan stimulates calcium-dependent signaling of IL-8 secretion by human airway epithelial cells
Eva M Carmona, Jeffrey D Lamont, Ailing Xue, Mark Wylam, Andrew H Limper
Lipocalin 2 is protective against E. coli pneumonia
Hong Wu, Eric Santoni-Rugiu, Elisabeth Ralfkiaer, Bo T Porse, Claus Moser, Niels Høiby, Niels Borregaard, Jack B Cowland
Alterations in the muscle-to-capillary interface in patients with different degrees of chronic obstructive pulmonary disease
Gabriella Eliason, Samy M Abdel-Halim, Karin Piehl-Aulin, Fawzi Kadi
Health status in COPD cannot be measured by the St George's Respiratory Questionnaire alone: an evaluation of the underlying concepts of this questionnaire
Leonie Daudey, Jeannette B Peters, Johan Molema, PN Richard Dekhuijzen, Judith B Prins, Yvonne F Heijdra, Jan H Vercoulen
Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation
Saskia Braber, Paul AJ Henricks, Frans P Nijkamp, Aletta D Kraneveld, Gert Folkerts
Different regulation of cigarette smoke induced inflammation in upper versus lower airways
Wouter Huvenne, Claudina A Pérez-Novo, Lara Derycke, Natalie De Ruyck, Olga Krysko, Tania Maes, Nele Pauwels, Lander Robays, Ken R Bracke, Guy Joos, Guy Brusselle, Claus Bachert
Host lung gene expression patterns predict infectious etiology in a mouse model of pneumonia
Scott E Evans, Michael J Tuvim, Jiexin Zhang, Derek T Larson, Cesar D García, Sylvia Martinez Pro, Kevin R Coombes, Burton F Dickey
NO2 inhalation induces maturation of pulmonary CD11c+ cells that promote antigen-specific CD4+ T cell polarization
Samantha R Hodgkins, Jennifer L Ather, Sara A Paveglio, Jenna L Allard, Laurie A Whittaker LeClair, Benjamin T Suratt, Jonathan E Boyson, Matthew E Poynter
Asthma and gender impact accumulation of T cell subtypes
Matthew J Loza, Susan Foster, Eugene R Bleecker, Stephen P Peters, Raymond B Penn
Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13
Yassine Amrani, Farhat Syed, Chris Huang, Katherine Li, Veronica Liu, Deepika Jain, Stefan Keslacy, Michael W Sims, Hasna Baidouri, Philip R Cooper, Hengjiang Zhao, Salman Siddiqui, Christopher E Brightling, Don Griswold, Lily Li, Reynold A Panettieri Jr
Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study
Amir Soltani, David W Reid, Sukhwinder S Sohal, Richard Wood-Baker, Steve Weston, H Konrad Muller, E Haydn Walters
Can AMP induce sputum eosinophils, even in subjects with complete asthma remission?
Franke Volbeda, Nick HT ten Hacken, Monique E Lodewijk, Antoon Dijkstra, Machteld N Hylkema, M Broekema, Wim Timens, Dirkje S Postma
The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats
Yu-Dong Xu, Jian-Mei Cui, Yu Wang, Lei-Miao Yin, Chang-Ke Gao, Yan-Yan Liu, Yong-Qing Yang
Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of the common cold
Ron Eccles, Christiane Meier, Martez Jawad, Regina Weinmüllner, Andreas Grassauer, Eva Prieschl-Grassauer
Effect of acute hypoxia on respiratory muscle fatigue in healthy humans
Samuel Verges, Damien Bachasson, Bernard Wuyam
Eotaxin-1 in exhaled breath condensate of stable and unstable asthma patients.
Ziemowit Zietkowski, Maria M Tomasiak-Lozowska, Roman Skiepko, Elzbieta Zietkowska, Anna Bodzenta-Lukaszyk
Pulmonary hemodynamic responses to in utero ventilation in very immature fetal sheep
Beth J Allison, Kelly J Crossley, Sharon J Flecknoe, Colin J Morley, Graeme R Polglase, Stuart B Hooper
Nordic Walking improves daily physical activities in COPD: a randomised controlled trial
Marie-Kathrin Breyer, Robab Breyer-Kohansal, Georg-Christian Funk, Nicole Dornhofer, Martijn A Spruit, Emiel FM Wouters, Otto C Burghuber, Sylvia Hartl
Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
Tamara Schikowski, Ulrich Ranft, Dorothee Sugiri, Andrea Vierkötter, Thomas Brüning, Volker Harth, Ursula Krämer
The presence of serum anti-Ascaris lumbricoides IgE antibodies and of Trichuris trichiura infection are risk factors for wheezing and/or atopy in preschool-aged Brazilian children
Neuza M Alcântara-Neves, Samuel J Badaró, Mariese CA dos Santos, Lain Pontes-de-Carvalho, Maurício L Barreto
Female sex hormones mediate the allergic lung reaction by regulating the release of inflammatory mediators and the expression of lung E-selectin in rats
Ana Paula Ligeiro de Oliveira, Jean Pierre Schatzmann Peron, Amilcar Sabino Damazo, Lino Adriana dos Santos Franco, Vanni Helori Domingos, Sonia Maria Oliani, Ricardo Martins Oliveira-Filho, Bernardo Boris Vargaftig, Wothan Tavares-de-Lima
Genome sequences of Human Adenovirus 14 isolates from mild respiratory cases and a fatal pneumonia, isolated during 2006-2007 epidemics in North America
Huo-Shu H Houng, Heping Gong, Adriana E Kajon, Morris S Jones, Robert A Kuschner, Arthur Lyons, Lisa Lott, Kuei-Hsiang Lin, David Metzgar
Helium-oxygen reduces the production of carbon dioxide during weaning from mechanical ventilation
Gordon Flynn, Gerlinde Mandersloot, Marie Healy, Mark Saville, Daniel F McAuley
Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice
Konstantinos Doris, Sophia P Karabela, Chrysoula A Kairi, Davina CM Simoes, Charis Roussos, Spyros G Zakynthinos, Ioannis Kalomenidis, Timothy S Blackwell, Georgios T Stathopoulos
Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury
Neal S Gould, Steve Gauthier, Chirag T Kariya, Elysia Min, Jie Huang, Brian J Day
Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma
Sandra D Anderson, David S Pearlman, Kenneth W Rundell, Claire P Perry, Homer Boushey, Christine A Sorkness, Sara Nichols, John M Weiler
No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis
Maria Wikén, Farah Idali, Muntasir Abo Al Hayja, Johan Grunewald, Anders Eklund, Jan Wahlström
Characterisation of COPD heterogeneity in the ECLIPSE cohort
Alvar Agusti, Peter MA Calverley, Bartolome Celli, Harvey O Coxson, Lisa D Edwards, David A Lomas, William MacNee, Bruce E Miller, Steve Rennard, Edwin K Silverman, Ruth Tal-Singer, Emiel Wouters, Julie C Yates, Jørgen Vestbo
Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD
Nobuhisa Ishikawa, Steffen Ohlmeier, Kaisa Salmenkivi, Marjukka Myllärniemi, Irfan Rahman, Witold Mazur, Vuokko L Kinnula
Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages
Jessica Hoppstädter, Britta Diesel, Robert Zarbock, Tanja Breinig, Dominik Monz, Marcus Koch, Andreas Meyerhans, Ludwig Gortner, Claus-Michael Lehr, Hanno Huwer, Alexandra K Kiemer
Respiratory Syncytial Virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice
Juan Pablo Torres, Ana M Gomez, Shama Khokhar, Vijay G Bhoj, Claudia Tagliabue, Michael L Chang, Peter A Kiener, Paula A Revell, Octavio Ramilo, Asuncion Mejias
Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation
Wing-Yan Heidi Wan, Abigail Morris, Gillian Kinnear, William Pearce, Joanie Mok, Daniel Wyss, Christopher S Stevenson
Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype
J Kelley Bentley, Antonia P Popova, Paul D Bozyk, Marisa J Linn, Amy E Baek, Jing Lei, Adam M Goldsmith, Marc B Hershenson
Cytotoxic T cells expressing the co-stimulatory receptor NKG2 D are increased in cigarette smoking and COPD
Ester Roos-Engstrand, Jamshid Pourazar, Annelie F Behndig, Anders Blomberg, Anders Bucht
Asthma susceptible genes in Chinese population: A meta-analysis
Xiaobo Li, Yonggang Zhang, Jie Zhang, Yuling Xiao, Jin Huang, Can Tian, Chao He, Yao Deng, Yingying Yang, Hong Fan
Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle
Tjitske A Oenema, Saeed Kolahian, Janke E Nanninga, Daniëlle Rieks, Pieter S Hiemstra, Suzanne Zuyderduyn, Andrew J Halayko, Herman Meurs, Reinoud Gosens
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression
Shyamala Ganesan, Andrea N Faris, Adam T Comstock, Sangbrita S Chattoraj, Asamanja Chattoraj, John R Burgess, Jeffrey L Curtis, Fernando J Martinez, Suzanna Zick, Marc B Hershenson, Uma S Sajjan
The role of the bronchial microvasculature in the airway remodelling in asthma and COPD
Andrea Zanini, Alfredo Chetta, Andrea S Imperatori, Antonio Spanevello, Dario Olivieri
Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration
Zbigniew Mikulski, Petra Hartmann, Gitte Jositsch, Zbigniew Zasłona, Katrin S Lips, Uwe Pfeil, Hjalmar Kurzen, Jürgen Lohmeyer, Wolfgang G Clauss, Veronika Grau, Martin Fronius, Wolfgang Kummer
Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner
Nele S Pauwels, Ken R Bracke, Tania Maes, Geert R Van Pottelberge, Cecilia Garlanda, Alberto Mantovani, Guy F Joos, Guy G Brusselle
Indacaterol provides 24-hour bronchodilation in COPD: a placebo-controlled blinded comparison with tiotropium
Claus Vogelmeier, David Ramos-Barbon, Damon Jack, Simon Piggott, Roger Owen, Mark Higgins, Benjamin Kramer
Therapeutic efficacy of alpha-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry
Robert A Stockley, David G Parr, Eeva Piitulainen, Jan Stolk, Berend C Stoel, Asger Dirksen
Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations
Donald R VanDevanter, Mary A O'Riordan, Jeffrey L Blumer, Michael W Konstan
Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma
Toby K McGovern, William S Powell, Brian J Day, Carl W White, Karuthapillai Govindaraju, Harry Karmouty-Quintana, Normand Lavoie, JuJing Tan, James G Martin
Expression and function of human hemokinin-1 in human and guinea pig airways
Stanislas Grassin-Delyle, Emmanuel Naline, Amparo Buenestado, Paul-André Risse, Edouard Sage, Charles Advenier, Philippe Devillier
Mutations that permit residual CFTR function delay acquisition of multiple respiratory pathogens in CF patients
Deanna M Green, Kathryn E McDougal, Scott M Blackman, Patrick R Sosnay, Lindsay B Henderson, Kathleen M Naughton, J Michael Collaco, Garry R Cutting
Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells
Virginie Prulière-Escabasse, Christine Clerici, Grégoire Vuagniaux, Andre Coste, Estelle Escudier, Carole Planès
Disrupted postnatal lung development in heme oxygenase-1 deficient mice
Tiangang Zhuang, Monica Zhang, Huayan Zhang, Phyllis A Dennery, Qing S Lin
Decreased Toll-like receptor 8 expression and lower TNF-alpha synthesis in infants with acute RSV infection
Kreso Bendelja, Valerija Vojvoda, Neda Aberle, Jasna Cepin-Bogovic, Alenka Gagro, Gordana Mlinaric-Galinovic, Sabina Rabatic
Habitual Snoring in school-aged children: environmental and biological predictors
Shenghui Li, Xinming Jin, Chonghuai Yan, Shenghu Wu, Fan Jiang, Xiaoming Shen
DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1
Petra Seidel, Stephanie Goulet, Katrin Hostettler, Michael Tamm, Michael Roth
Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis
Sevdalina Nikolova, Andreas Guenther, Rajkumar Savai, Norbert Weissmann, Hossein A Ghofrani, Melanie Konigshoff, Oliver Eickelberg, Walter Klepetko, Robert Voswinckel, Werner Seeger, Friedrich Grimminger, Ralph T Schermuly, Soni S Pullamsetti
Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro
Suki MY Lee, Renee WY Chan, Jennifer L Gardy, Cheuk-kin Lo, Alan DL Sihoe, Sara SR Kang, Timothy KW Cheung, Yi Guan, Michael CW Chan, Robert EW Hancock, Malik JS Peiris
MicroRNAs in inflammatory lung disease - master regulators or target practice?
Irene K Oglesby, Noel G McElvaney, Catherine M Greene
Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents
Donald P Tashkin, Leonardo M Fabbri
Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium
Guoqing Wang, Rui Wang, Barbara Ferris, Jacqueline Salit, Yael Strulovici-Barel, Neil R Hackett, Ronald G Crystal
Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep
Noah H Hillman, Suhas G Kallapur, J Jane Pillow, Ilias Nitsos, Graeme R Polglase, Machiko Ikegami, Alan H Jobe
The role of leptin in the respiratory system: an overview
Foteini Malli, Andriana I Papaioannou, Konstantinos I Gourgoulianis, Zoe Daniil
Quantification of lung surface area using computed tomography
Ren Yuan, Taishi Nagao, Peter D Paré, James C Hogg, Don D Sin, Mark W Elliott, Leanna Loy, Li Xing, Steven E Kalloger, John C English, John R Mayo, Harvey O Coxson
Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13
Jae Youn Cho, Dae Jae Song, Alexa Pham, Peter Rosenthal, Marina Miller, Shanna Dayan, Taylor A Doherty, Ajit Varki, David H Broide
SPLUNC1 regulation in airway epithelial cells: role of toll-like receptor 2 signaling
Hong Wei Chu, Fabienne Gally, Jyoti Thaikoottathil, Yvonne M Janssen-Heininger, Qun Wu, Gongyi Zhang, Nichole Reisdorph, Stephanie Case, Maisha Minor, Sean Smith, Di Jiang, Nicole Michels, Glenn Simon, Richard J Martin
Neurotrophins and neurotrophin receptors in pulmonary sarcoidosis - granulomas as a source of expression
Charlotta Dagnell, Johan Grunewald, Marija Kramar, Helga Haugom-Olsen, Göran P Elmberger, Anders Eklund, Caroline Olgart Höglund
The effect of interleukin-13 (IL-13) and interferon-γ (IFN-γ) on expression of surfactant proteins in adult human alveolar type II cells in vitro
Yoko Ito, Robert J Mason
Legionella pneumophila induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages
Yoshitomo Morinaga, Katsunori Yanagihara, Shigeki Nakamura, Hiroo Hasegawa, Masafumi Seki, Koichi Izumikawa, Hiroshi Kakeya, Yoshihiro Yamamoto, Yasuaki Yamada, Shigeru Kohno, Shimeru Kamihira
Involvement of microRNAs in physiological and pathological processes in the lung
Tereza Tomankova, Martin Petrek, Eva Kriegova
Oral tolerance inhibits pulmonary eosinophilia in a cockroach allergen induced model of asthma: a randomized laboratory study
Louis J Vaickus, Jacqueline Bouchard, Jiyoun Kim, Sudha Natarajan, Daniel G Remick
Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis
Kyra A Oswald-Richter, Dia C Beachboard, Xiaoyan Zhan, Christa F Gaskill, Susamma Abraham, Cathy Jenkins, Daniel A Culver, Wonder Drake
Airway branching morphogenesis in three dimensional culture
Sigrídur R Franzdóttir, Ivar T Axelsson, Ari J Arason, Ólafur Baldursson, Thorarinn Gudjonsson, Magnus K Magnusson
Multi-symptom asthma is closely related to nasal blockage, rhinorrhea and symptoms of chronic rhinosinusitis-evidence from the West Sweden Asthma Study
Jan Lötvall, Linda Ekerljung, Bo Lundbäck
Expression of neutral endopeptidase activity during clinical and experimental acute lung injury
Soshi Hashimoto, Fumimasa Amaya, Kentaro Oh-hashi, Kazutoshi Kiuchi, Satoru Hashimoto
Variability in the precursor proteins of collagen I and III in different stages of COPD
Terttu Harju, Vuokko L Kinnula, Paavo Pääkkö, Kaisa Salmenkivi, Juha Risteli, Riitta Kaarteenaho
Estrogen aggravates inflammation in Pseudomonas aeruginosa pneumonia in cystic fibrosis mice
Yufa Wang, Elvis Cela, Stéphane Gagnon, Neil B Sweezey
Poverty, dirt, infections and non-atopic wheezing in children from a Brazilian urban center
Mauricio L Barreto, Sergio S Cunha, Rosemeire Fiaccone, Renata Esquivel, Leila D Amorim, Sheila Alvim, Matildes Prado, Alvaro A Cruz, Philip J Cooper, Darci N Santos, Agostino Strina, Neuza Alcantara-Neves, Laura C Rodrigues
Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation
Bo Liu, Samantha E Peel, Jane Fox, Ian P Hall
New approaches in the diagnosis and treatment of latent tuberculosis infection
Suhail Ahmad
The laminin β1-competing peptide YIGSR induces a hypercontractile, hypoproliferative airway smooth muscle phenotype in an animal model of allergic asthma
Bart GJ Dekkers, I Sophie T Bos, Andrew J Halayko, Johan Zaagsma, Herman Meurs
A systematic review of the role of vitamin insufficiencies and supplementation in COPD
Ioanna G Tsiligianni, Thys van der Molen
JNK activation is responsible for mucus overproduction in smoke inhalation injury
Won-II Choi, Olga Syrkina, KunYoung Kwon, Deborah A Quinn, Charles A Hales
Cardiovascular and musculskeletal co-morbidities in patients with alpha 1 antitrypsin deficiency
James M Duckers, Dennis J Shale, Robert A Stockley, Nichola S Gale, Bronwen AJ Evans, John R Cockcroft, Charlotte E Bolton
Population specificity of the DNAI1 gene mutation spectrum in primary ciliary dyskinesia (PCD)
Ewa Ziętkiewicz, Barbara Nitka, Katarzyna Voelkel, Urszula Skrzypczak, Zuzanna Bukowy, Ewa Rutkiewicz, Kinga Humińska, Hanna Przystałowska, Andrzej Pogorzelski, Michał Witt
TTF-1 regulates α5 nicotinic acetylcholine receptor (nAChR) subunits in proximal and distal lung epithelium
Paul R Reynolds, Camille H Allison, Charles P Willnauer
Serum adiponectin is positively associated with lung function in young adults, independent of obesity: The CARDIA study
Bharat Thyagarajan, David R Jacobs Jr, Lewis J Smith, Ravi Kalhan, Myron D Gross, Akshay Sood
Elevated expression of both mRNA and protein levels of IL-17A in sputum of stable Cystic Fibrosis patients
Ann Decraene, Anna Willems-Widyastuti, Ahmad Kasran, Kris De Boeck, Dominique M Bullens, Lieven J Dupont
Corticosteroid effects on ventilator-induced diaphragm dysfunction in anesthetized rats depend on the dose administered
Karen Maes, Anouk Agten, Ashley Smuder, Scott K Powers, Marc Decramer, Ghislaine Gayan-Ramirez
Immunomodulatory strategies prevent the development of autoimmune emphysema
Masayuki Hanaoka, Mark R Nicolls, Andrew P Fontenot, Donatas Kraskauskas, Douglas G Mack, Adelheid Kratzer, Jonas Salys, Vita Kraskauskiene, Nana Burns, Norbert F Voelkel, Laimute Taraseviciene-Stewart
Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease
Tillie L Hackett, Marco Scarci, Lu Zheng, Wan Tan, Tom Treasure, Jane A Warner
Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1
Thomas Rodt, Christian von Falck, Sabine Dettmer, Roman Halter, Regina Maus, Kjetil Ask, Martin Kolb, Jack Gauldie, Florian Länger, Ludwig Hoy, Tobias Welte, Michael Galanski, Ulrich A Maus, Jürgen Borlak
Beta-estradiol attenuates hypoxic pulmonary hypertension by stabilizing the expression of p27kip1 in rats
Dun-Quan Xu, Ying Luo, Yi Liu, Jing Wang, Bo Zhang, Min Xu, Yan-Xia Wang, Hai-Ying Dong, Ming-Qing Dong, Peng-Tao Zhao, Wen Niu, Man-Ling Liu, Yu-Qi Gao, Zhi-Chao Li
The Role of Catalase in Pulmonary Fibrosis
Nao Odajima, Tomoko Betsuyaku, Katsura Nagai, Chinatsu Moriyama, Da-Hong Wang, Tomoko Takigawa, Keiki Ogino, Masaharu Nishimura
Adaptive immunity to rhinoviruses: sex and age matter
Melanie L Carroll, Stephanie T Yerkovich, Antonia L Pritchard, Janet M Davies, John W Upham