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Allergy, Asthma & Clinical Immunology

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Open Access 01-12-2022 | Primary Immunodeficiency | Case report

Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature

Authors: David X. Gao, Habiba Hussain, Brianna Bobber, Peter Phan

Published in: Allergy, Asthma & Clinical Immunology | Issue 1/2022

Abstract

Background

Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder associated with a broad symptom presentation that is still being characterized. We report a rare case of recurrent mycoplasma skin abscesses in a patient with a history of autoimmune disorders and prolonged mycoplasma pneumonia who was diagnosed with CVID.

Case presentation

A 34-year-old woman presented with a history of recurrent abscesses previously confirmed positive for Mycoplasma pneumoniae. Her past medical history of recurrent mycoplasma abscesses, prolonged mycoplasma pneumonia, and autoimmune disorders (mixed connective tissue disease and immune thrombocytopenia) raised suspicion of CVID. Workup included negative anti-mycoplasma antibody titers, hypogammaglobulinemia, and negative anti-pneumococcal antibody titers despite prior vaccination, solidifying the diagnosis of CVID. The patient was discharged on antibiotic and intravenous immunoglobulin therapy and now follows allergy and immunology long-term for treatment.

Conclusions

Her diagnostic history underscores the importance of considering the various criteria of CVID for diagnosis, and her unique presentation of M. pneumoniae skin abscesses highlights the broad sequelae patients with CVID can manifest.

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Title: Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature
Authors: David X. Gao
Habiba Hussain
Brianna Bobber
Peter Phan
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Primary Immunodeficiency
Immunodeficiency
Pneumonia
Mixed Connective Tissue Disease
Published in: Allergy, Asthma & Clinical Immunology / Issue 1/2022
Electronic ISSN: 1710-1492
DOI: https://doi.org/10.1186/s13223-022-00673-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Turning walking pneumonia into recurrent abscesses: a curious case of CVID and review of the literature

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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