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Published in: Journal of Bone and Mineral Metabolism 5/2021

01-09-2021 | Osteoporosis | Original Article

Stand-up test predicts occurrence of non-traumatic vertebral fracture in outpatient women with osteoporosis

Authors: Ryoma Asahi, Yutaka Nakamura, Masayoshi Kanai, Kento Watanabe, Satoshi Yuguchi, Tomohiko Kamo, Masato Azami, Hirofumi Ogihara, Satoshi Asano

Published in: Journal of Bone and Mineral Metabolism | Issue 5/2021

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Abstract

Introduction

The purpose of this retrospective study was to clarify the incidence of non-traumatic vertebral fracture among outpatient women with osteoporosis and to determine whether the stand-up test predicted the occurrence of non-traumatic vertebral fracture.

Materials and methods

A total of 242 postmenopausal women over 60 years of age who received outpatient osteoporosis treatment at our hospital between November 2013 and July 2020 were longitudinally evaluated in this study. We obtained medical information and radiographic parameters, including sagittal vertical axis, thoracic kyphosis, pelvic incidence, lumbar lordosis, pelvic tilt, and sacral slope at baseline. Additionally, we measured physical parameters, including height, weight, body mass index, lumbar bone mineral density, visual analog scale score for pain, and the stand-up test.

Results

Vertebral fractures occurred in 20 of 242 participants (8.3%), and accounted for 48.8% the 41 total fractures in the study group. Among vertebral fractures, eight (40.0%) were traumatic, resulting from falls, and 12 (60.0%) were non-traumatic. Cox multivariate logistic regression analysis adjusted for age, body mass index, lumbar bone mineral density, and the time to non-traumatic vertebral fracture showed that the sagittal vertical axis (HR = 1.013, 95% CI 1.001–1.026), stand-up test score (HR = 3.977, 95% CI 1.156–13.683), and presence of difficulty with standing from a 20-cm-high seat using both legs (HR = 3.329, 95% CI 1.625–6.82) were independent risk factors for the occurrence of non-traumatic vertebral fracture.

Conclusion

The stand-up test may be useful as a simple screening tool for non-traumatic vertebral fracture in patients with osteoporosis.
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Metadata
Title
Stand-up test predicts occurrence of non-traumatic vertebral fracture in outpatient women with osteoporosis
Authors
Ryoma Asahi
Yutaka Nakamura
Masayoshi Kanai
Kento Watanabe
Satoshi Yuguchi
Tomohiko Kamo
Masato Azami
Hirofumi Ogihara
Satoshi Asano
Publication date
01-09-2021
Publisher
Springer Singapore
Published in
Journal of Bone and Mineral Metabolism / Issue 5/2021
Print ISSN: 0914-8779
Electronic ISSN: 1435-5604
DOI
https://doi.org/10.1007/s00774-021-01229-y

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