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BMC Oral Health

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Open Access 01-12-2023 | Nutrition | Research

Association between periodontitis and osteoporosis in United States adults from the National Health and Nutrition Examination Survey: a cross-sectional analysis

Authors: Jing Peng, Jianming Chen, Yucheng Liu, Jun Lyu, Bin Zhang

Published in: BMC Oral Health | Issue 1/2023

Abstract

Objective

This cross-sectional study aimed to investigate the association between periodontitis and osteoporosis among US adults as well as the subgroup of menopausal women.

Background

Periodontitis and osteoporosis are both chronic inflammatory diseases characterized by local or systemic bone resorption. Since they share many risk factors, and the significant decrease in estrogen along with menopause is unfavorable for both diseases, it’s reasonable to assume that there exists some links between the two diseases, especially during the menopause.

Methods

We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2009–2010 and 2013–2014. Periodontitis (defined according to the CDC/AAP definition) and osteoporosis (assessed by the dual-energy radiation absorptiometry) data were available for 5736 participants, and 519 subjects were enrolled in the subgroup of menopausal women aged 45–60 years old. We used binary logistic regression analysis to examine the association between the two diseases both in crude and fully adjusted model.

Results

In the fully adjusted model, osteoporosis was significantly associated with an increased risk of periodontal disease (OR:1.66, 95% CI: 1.00–2.77) in the whole population. As to the subgroup of menopausal women, osteoporosis group had an adjusted OR of 9.66 (95% CI: 1.13–82.38) for developing severe periodontitis in the fully adjusted model.

Conclusions

Osteoporosis is significantly associated with periodontitis and the association is even more pronounced in menopausal women with severe periodontitis.

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Title: Association between periodontitis and osteoporosis in United States adults from the National Health and Nutrition Examination Survey: a cross-sectional analysis
Authors: Jing Peng
Jianming Chen
Yucheng Liu
Jun Lyu
Bin Zhang
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Nutrition
Osteoporosis
Osteoporosis
Gingival Diseases
Estrogens
Published in: BMC Oral Health / Issue 1/2023
Electronic ISSN: 1472-6831
DOI: https://doi.org/10.1186/s12903-023-02990-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Association between periodontitis and osteoporosis in United States adults from the National Health and Nutrition Examination Survey: a cross-sectional analysis

Abstract

Objective

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Background

Methods

Results

Conclusions

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