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Current Osteoporosis Reports
Published in: Current Osteoporosis Reports 6/2016

01-12-2016 | Craniofacial Skeleton (E Roberts, Section Editor)

Osteoporosis and Periodontitis

Authors: Chin-Wei (Jeff) Wang, Laurie K. McCauley

Published in: Current Osteoporosis Reports | Issue 6/2016

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Abstract

Osteoporosis and periodontitis are both diseases characterized by bone resorption. Osteoporosis features systemic degenerative bone loss that leads to loss of skeletal cancellous microstructure and subsequent fracture, whereas periodontitis involves local inflammatory bone loss, following an infectious breach of the alveolar cortical bone, and it may result in tooth loss. Most cross-sectional studies have confirmed the association of osteoporosis and periodontitis primarily on radiographic measurements and to a lesser degree on clinical parameters. Multiple shared risk factors include age, genetics, hormonal change, smoking, as well as calcium and vitamin D deficiency. Both diseases could also be risk factors for each other and have a mutual impact that requires concomitant management. Suggested mechanisms underlying the linkage are disruption of the homeostasis concerning bone remodeling, hormonal balance, and inflammation resolution. A mutual interventional approach is emerging with complex treatment interactions. Prevention and management of both diseases require interdisciplinary approaches and warrants future well-controlled longitudinal and interventional studies for evidence-based clinical guidelines.
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Metadata
Title
Osteoporosis and Periodontitis
Authors
Chin-Wei (Jeff) Wang
Laurie K. McCauley
Publication date
01-12-2016
Publisher
Springer US
Published in
Current Osteoporosis Reports / Issue 6/2016
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-016-0330-3

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