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Published in: Medical Microbiology and Immunology 2/2012

01-05-2012 | Rapid Communication

No evidence for a role of xenotropic murine leukaemia virus-related virus and BK virus in prostate cancer of German patients

Authors: Baki Akgül, David Pfister, Ruth Knüchel, Axel Heidenreich, Ulrike Wieland, Herbert Pfister

Published in: Medical Microbiology and Immunology | Issue 2/2012

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Abstract

Prostate cancer is one of the most prevalent types of cancer in men. Controversial data exist concerning the role of BKPyV and the xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) in prostate cancer development. We therefore assessed the association between prostate cancer and viral infections. We could detect BKPyV in only 1 out of 85 prostate cancer samples, whereas none of the tissue samples showed evidence for XMRV positivity. Lack of detection of BKPyV and XMRV in prostate cancer tissues suggests that these viruses do not play a role in the pathogenesis of this type of cancer.
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Metadata
Title
No evidence for a role of xenotropic murine leukaemia virus-related virus and BK virus in prostate cancer of German patients
Authors
Baki Akgül
David Pfister
Ruth Knüchel
Axel Heidenreich
Ulrike Wieland
Herbert Pfister
Publication date
01-05-2012
Publisher
Springer-Verlag
Published in
Medical Microbiology and Immunology / Issue 2/2012
Print ISSN: 0300-8584
Electronic ISSN: 1432-1831
DOI
https://doi.org/10.1007/s00430-011-0215-0

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