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Medical Microbiology and Immunology
Published in: Medical Microbiology and Immunology 1/2011

01-02-2011 | Review

Oncomodulation by human cytomegalovirus: novel clinical findings open new roads

Authors: Martin Michaelis, Peter Baumgarten, Michel Mittelbronn, Pablo Hernáiz Driever, Hans Wilhelm Doerr, Jindrich Cinatl Jr.

Published in: Medical Microbiology and Immunology | Issue 1/2011

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Abstract

The question whether human cytomegalovirus may affect cancer diseases has been discussed (very controversially) for decades. There are convinced believers and strict opponents of the idea that HCMV might be able to play a role in the course of cancer diseases. In parallel, the number of published reports on the topic is growing. Recently published and presented (Ranganathan P, Clark P, Kuo JS, Salamat S, Kalejta RF. A Survey of Human Cytomegalovirus Genomic Loci Present in Glioblastoma Multiforme Tissue Samples. 35th Annual International Herpes Workshop, Salt Lake City, 2010) data on HCMV detection in glioblastoma tissues and colocalisation of HCMV proteins with cellular proteins known to be relevant for glioblastoma progression motivated us to recapitulate the current state of evidence.
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Metadata
Title
Oncomodulation by human cytomegalovirus: novel clinical findings open new roads
Authors
Martin Michaelis
Peter Baumgarten
Michel Mittelbronn
Pablo Hernáiz Driever
Hans Wilhelm Doerr
Jindrich Cinatl Jr.
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Medical Microbiology and Immunology / Issue 1/2011
Print ISSN: 0300-8584
Electronic ISSN: 1432-1831
DOI
https://doi.org/10.1007/s00430-010-0177-7

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