Issue 1/2007
Content (83 Articles)
Nasopharyngeal carcinoma: molecular biomarker discovery and progress
William Chi-shing Cho
Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
Kristine Kleivi, Guro E Lind, Chieu B Diep, Gunn I Meling, Lin T Brandal, Jahn M Nesland, Ola Myklebost, Torleiv O Rognum, Karl-Erik Giercksky, Rolf I Skotheim, Ragnhild A Lothe
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells
Sieta P Rao, Markus P Rechsteiner, Christoph Berger, Jürg A Sigrist, David Nadal, Michele Bernasconi
PTTG expression in different experimental and human prolactinomas in relation to dopaminergic control of lactotropes
Carolina Cristina, Graciela S Díaz-Torga, Rodolfo G Goya, Sham S Kakar, María I Perez-Millán, Vanessa Q Passos, Daniel Giannella-Neto, Marcello D Bronstein, Damasia Becu-Villalobos
High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma
Carla Hebert, Kathleen Norris, Mark A Scheper, Nikolaos Nikitakis, John J Sauk
Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation
Rajeev S Samant, David W Clark, Rebecca A Fillmore, Muzaffer Cicek, Brandon J Metge, Kondethimmana H Chandramouli, Ann F Chambers, Graham Casey, Danny R Welch, Lalita A Shevde
Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized
Yizheng Li, Jing Pan, Jian-Liang Li, Jee Hyung Lee, Chris Tunkey, Katie Saraf, James C Garbe, Maryann Z Whitley, Scott A Jelinsky, Martha R Stampfer, Steven A Haney
Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells
Marina Pisano, Gabriella Pagnan, Monica Loi, Maria Elena Mura, Maria Giovanna Tilocca, Giuseppe Palmieri, Davide Fabbri, Maria Antonietta Dettori, Giovanna Delogu, Mirco Ponzoni, Carla Rozzo
Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression
Zhong Wang, Philip S Lecane, Patricia Thiemann, Qing Fan, Cecilia Cortez, Xuan Ma, Danielle Tonev, Dale Miles, Louie Naumovski, Richard A Miller, Darren Magda, Dong-Gyu Cho, Jonathan L Sessler, Brian L Pike, Samantha M Yeligar, Mazen W Karaman, Joseph G Hacia
Identification of candidate methylation-responsive genes in ovarian cancer
Laura Menendez, DeEtte Walker, Lilya V Matyunina, Erin B Dickerson, Nathan J Bowen, Nalini Polavarapu, Benedict B Benigno, John F McDonald
MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo
Began Gopalan, Manish Shanker, Sunil Chada, Rajagopal Ramesh
Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers
Christina E Hoei-Hansen, Sigrid M Kraggerud, Vera M Abeler, Janne Kærn, Ewa Rajpert-De Meyts, Ragnhild A Lothe
Integrative analysis of a cancer somatic mutome
Pilar Hernández, Xavier Solé, Joan Valls, Víctor Moreno, Gabriel Capellá, Ander Urruticoechea, Miguel Angel Pujana
Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
Wolfgang A Schulz, Adrian Alexa, Volker Jung, Christiane Hader, Michèle J Hoffmann, Masanori Yamanaka, Sandy Fritzsche, Agnes Wlazlinski, Mirko Müller, Thomas Lengauer, Rainer Engers, Andrea R Florl, Bernd Wullich, Jörg Rahnenführer
Modeling survival in colon cancer: a methodological review
Farid E Ahmed, Paul W Vos, Don Holbert
Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance
Pei-Yin Lin, Susan P Fosmire, See-Hyoung Park, Jin-Young Park, Shairaz Baksh, Jaime F Modiano, Robert H Weiss
Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer
Linda Ulazzi, Silvia Sabbioni, Elena Miotto, Angelo Veronese, Angela Angusti, Roberta Gafà, Stefano Manfredini, Fabio Farinati, Takako Sasaki, Giovanni Lanza, Massimo Negrini
Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells
Bhavik Desai, Michael J Rogers, Meenakshi A Chellaiah
Hedgehog pathway activity in the LADY prostate tumor model
Jerry Gipp, Guangyu Gu, Curtis Crylen, Susan Kasper, Wade Bushman
Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues
Prakasha Kempaiah, Hitendra S Chand, Walter Kisiel
Effect of BRAFV600E mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model
Susanne Cahill, Paul Smyth, Karen Denning, Richard Flavin, Jinghuan Li, Astrid Potratz, Simone M Guenther, Richard Henfrey, John J O'Leary, Orla Sheils
Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model
Jinwei Hu, Xiangpeng Yuan, MinHee K Ko, Dali Yin, Manuel R Sacapano, Xiao Wang, Bindu M Konda, Andres Espinoza, Ksenia Prosolovich, John M Ong, Dwain Irvin, Keith L Black
Bright/ARID3A contributes to chromatin accessibility of the immunoglobulin heavy chain enhancer
Danjuan Lin, Gregory C Ippolito, Rui-Ting Zong, James Bryant, Janet Koslovsky, Philip Tucker
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention
John P Alao
Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications
Minal Vaish
Some facts and thoughts: p73 as a tumor suppressor gene in the network of tumor suppressors
Lakshmanane Boominathan
HHV-8 encoded LANA-1 alters the higher organization of the cell nucleus
György Stuber, Karin Mattsson, Emilie Flaberg, Emrah Kati, Laszlo Markasz, Julie A Sheldon, George Klein, Thomas F Schulz, Laszlo Szekely
Cancer cell: using inflammation to invade the host
José-Ignacio Arias, María-Angeles Aller, Jaime Arias
A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII
Dimitri G Trembath, Anita Lal, David J Kroll, Nicholas H Oberlies, Gregory J Riggins
LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro
Tien-sheng Huang, Line M Myklebust, Endre Kjarland, Bjørn Tore Gjertsen, Frederic Pendino, Øystein Bruserud, Stein Ove Døskeland, Johan R Lillehaug
N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma
Takeaki Kudo, Hiroaki Nakagawa, Masato Takahashi, Jun Hamaguchi, Naoya Kamiyama, Hideki Yokoo, Kazuaki Nakanishi, Takahito Nakagawa, Toshiya Kamiyama, Kisaburo Deguchi, Shin-Ichiro Nishimura, Satoru Todo
Pre-apoptotic response to therapeutic DNA damage involves protein modulation of Mcl-1, Hdm2 and Flt3 in acute myeloid leukemia cells
Line Wergeland, Gry Sjøholt, Ingvild Haaland, Randi Hovland, Øystein Bruserud, Bjørn Tore Gjertsen
A doxycycline-inducible urokinase receptor (uPAR) upregulates uPAR activities including resistance to anoikis in human prostate cancer cell lines
Mohammad Hasanuzzaman, Robert Kutner, Siamak Agha-Mohammadi, Jakob Reiser, Inder Sehgal
t(8;14;18): A 3-way chromosome translocation in two patients with Burkitt's lymphoma/leukemia
Delong Liu, Josif Shimonov, Suneeta Primanneni, Yongrong Lai, Tauseef Ahmed, Karen Seiter
O 6 -methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies
Ken Sasai, Tsuyoshi Akagi, Eiko Aoyanagi, Kouichi Tabu, Sadao Kaneko, Shinya Tanaka
hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands
Mohamed M Desouki, Joseph Geradts, Beatrice Milon, Renty B Franklin, Leslie C Costello
Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells
Katia Margiotti, Latif A Wafa, Helen Cheng, Giuseppe Novelli, Colleen C Nelson, Paul S Rennie
Identification of novel androgen receptor target genes in prostate cancer
Unnati Jariwala, Jennifer Prescott, Li Jia, Artem Barski, Steve Pregizer, Jon P Cogan, Armin Arasheben, Wayne D Tilley, Howard I Scher, William L Gerald, Grant Buchanan, Gerhard A Coetzee, Baruch Frenkel
Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer
Monica Davila, Darshana Jhala, Debashis Ghosh, William E Grizzle, Ratna Chakrabarti
In vivo optical imaging of integrin αV-β3 in mice using multivalent or monovalent cRGD targeting vectors
Zhao-Hui Jin, Véronique Josserand, Stéphanie Foillard, Didier Boturyn, Pascal Dumy, Marie-Christine Favrot, Jean-Luc Coll
Differential expression and role of p21cip/waf1 and p27kip1 in TNF-α-induced inhibition of proliferation in human glioma cells
Pabbisetty Sudheer Kumar, Anjali Shiras, Gowry Das, Jayashree C Jagtap, Vandna Prasad, Padma Shastry
Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth
Thaysa Paschoalin, Adriana K Carmona, Elaine G Rodrigues, Vitor Oliveira, Hugo P Monteiro, Maria A Juliano, Luiz Juliano, Luiz R Travassos
DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
Qinghua Wu, Ragnhild A Lothe, Terje Ahlquist, Ilvars Silins, Claes G Tropé, Francesca Micci, Jahn M Nesland, Zhenhe Suo, Guro E Lind
Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy
Tapas K Sengupta, Gilles M Leclerc, Ting Ting Hsieh-Kinser, Guy J Leclerc, Inderjit Singh, Julio C Barredo
Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma
Emmanuel Rousseau, Thomas Palm, Francesco Scaravilli, Marie-Magdeleine Ruchoux, Dominique Figarella-Branger, Isabelle Salmon, David Ellison, Catherine Lacroix, Françoise Chapon, Jacqueline Mikol, Miikka Vikkula, Catherine Godfraind
Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy
Hiroyuki Kashiwagi, Jonathan E McDunn, Peter O Simon Jr, Peter S Goedegebuure, Jinbin Xu, Lynne Jones, Katherine Chang, Fabian Johnston, Kathryn Trinkaus, Richard S Hotchkiss, Robert H Mach, William G Hawkins
RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis
Inga Peters, Kristina Rehmet, Nadine Wilke, Markus A Kuczyk, Jörg Hennenlotter, Tyark Eilers, Stefan Machtens, Udo Jonas, Jürgen Serth
In silico gene expression analysis – an overview
David Murray, Peter Doran, Padraic MacMathuna, Alan C Moss
MOZ-TIF2 repression of nuclear receptor-mediated transcription requires multiple domains in MOZ and in the CID domain of TIF2
Hong Yin, Jonathan Glass, Kerry L Blanchard
Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer
Daohai Zhang, Lee Lee Wong, Evelyn SC Koay
Molecular portrait of cisplatin induced response in human testis cancer cell lines based on gene expression profiles
Nur Duale, Birgitte Lindeman, Mitsuko Komada, Ann-Karin Olsen, Ashild Andreassen, Erik J Soderlund, Gunnar Brunborg
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer
Giovanni Lanza, Manuela Ferracin, Roberta Gafà, Angelo Veronese, Riccardo Spizzo, Flavia Pichiorri, Chang-gong Liu, George A Calin, Carlo M Croce, Massimo Negrini
Sodium Ascorbate induces apoptosis in neuroblastoma cell lines by interfering with iron uptake
Roberta Carosio, Guendalina Zuccari, Isabella Orienti, Salvatore Mangraviti, Paolo G Montaldo
Functional analysis of cancer-associated EGFR mutants using a cellular assay with YFP-tagged EGFR intracellular domain
Matheus M de Gunst, Marielle I Gallegos-Ruiz, Giuseppe Giaccone, Jose Antonio Rodriguez
Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells
Kelly C Heim, Kristina A White, Dexin Deng, Craig R Tomlinson, Jason H Moore, Sarah J Freemantle, Michael J Spinella
Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines
Jun Hamaguchi, Hiroaki Nakagawa, Masato Takahashi, Takeaki Kudo, Naoya Kamiyama, Bailong Sun, Takahiro Oshima, Yuji Sato, Kisaburo Deguchi, Satoru Todo, Shin-Ichiro Nishimura
Estrogenic or antiestrogenic therapies for multiple myeloma?
Brigitte Sola, Jack-Michel Renoir
Differential effects of hypoxia on etoposide-induced apoptosis according to the cancer cell lines
Jean-Philippe Cosse, Audrey Sermeus, Kayleen Vannuvel, Noelle Ninane, Martine Raes, Carine Michiels
Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakia
Kosei Ishida, Satoshi Ito, Naoyuki Wada, Hiroyo Deguchi, Tsuyoshi Hata, Masaru Hosoda, Tsutomu Nohno
Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1α
Yang Lu, Ke Liang, Xinqun Li, Zhen Fan
Molecular signatures define two main classes of meningiomas
Lucia Helena Carvalho, Ivan Smirnov, Gilson S Baia, Zora Modrusan, Justin S Smith, Peter Jun, Joseph F Costello, Michael W McDermott, Scott R VandenBerg, Anita Lal
Role of PP2Cα in cell growth, in radio- and chemosensitivity, and in tumorigenicity
Twan Lammers, Peter Peschke, Volker Ehemann, Jürgen Debus, Boris Slobodin, Sara Lavi, Peter Huber
Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin
Larisa L Belyanskaya, Thomas M Marti, Sally Hopkins-Donaldson, Stefanie Kurtz, Emanuela Felley-Bosco, Rolf A Stahel
Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia
Pavinder Kaur, Niklas Feldhahn, Bin Zhang, Daniel Trageser, Markus Müschen, Veerle Pertz, John Groffen, Nora Heisterkamp
Enhancing the anti-angiogenic action of histone deacetylase inhibitors
Selena Kuljaca, Tao Liu, Andrew EL Tee, Michelle Haber, Murray D Norris, Tanya Dwarte, Glenn M Marshall
A novel activating role of SRC and STAT3 on HGF transcription in human breast cancer cells
Michelle R Sam, Bruce E Elliott, Christopher R Mueller
Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma
Jeffrey A Tsou, Janice S Galler, Kimberly D Siegmund, Peter W Laird, Sally Turla, Wendy Cozen, Jeffrey A Hagen, Michael N Koss, Ite A Laird-Offringa
Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF
Ken-ichi Fujita, Siegfried Janz
Book Review of "The Molecular Biology of Cancer" by Stella Pelengaris, Michael Khan (Editors)
Christian Schmidt
The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells
Jens Voortman, Agnieszka Chęcińska, Giuseppe Giaccone
Alterations of GPI transamidase subunits in head and neck squamous carcinoma
Wei-Wen Jiang, Marianna Zahurak, Zeng-Tong Zhou, Hannah Lui Park, Zhong-Min Guo, Guo-Jun Wu, David Sidransky, Barry Trink, Joseph A Califano
Gene expression profiling of cancer stem cell in human lung adenocarcinoma A549 cells
Dong-Cheol Seo, Ji-Min Sung, Hee-Jung Cho, Hee Yi, Kun-Ho Seo, In-Soo Choi, Dong-Ku Kim, Jin-Suk Kim, Abd El-Aty AM, Ho-Chul Shin
Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel
Pinar Uysal-Onganer, Mustafa BA Djamgoz
The oncoprotein H-RasV12 increases mitochondrial metabolism
Sucheta Telang, Andrew N Lane, Kristin K Nelson, Sengodagounder Arumugam, Jason Chesney
Genome-wide expression patterns of invasion front, inner tumor mass and surrounding normal epithelium of colorectal tumors
Eike Staub, Joern Groene, Maya Heinze, Detlev Mennerich, Stefan Roepcke, Irina Klaman, Bernd Hinzmann, Esmeralda Castanos-Velez, Christian Pilarsky, Benno Mann, Thomas Brümmendorf, Birgit Weber, Heinz-Johannes Buhr, André Rosenthal
Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells
Gaëlle Tilman, Marina Mattiussi, Francis Brasseur, Nicolas van Baren, Anabelle Decottignies
Fra-1 governs cell migration via modulation of CD44 expression in human mesotheliomas
Maria E Ramos-Nino, Steven R Blumen, Harvey Pass, Brooke T Mossman
On the role of transforming growth factor-β in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells
Brahmchetna Singh, Richard F Murphy, Xian-Zhong Ding, Alexandra B Roginsky, Richard H Bell Jr, Thomas E Adrian
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion
Hany Kayed, Sandor Bekasi, Shereen Keleg, Christoph W Michalski, Thomas Giese, Helmut Friess, Jörg Kleeff