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Open Access 01-12-2018 | Mini review

Intrauterine growth restriction - impact on cardiovascular diseases later in life

Authors: Carlos Menendez-Castro, Wolfgang Rascher, Andrea Hartner

Published in: Molecular and Cellular Pediatrics | Issue 1/2018

Abstract

Intrauterine growth restriction (IUGR) is a fetal pathology which leads to increased risk for certain neonatal complications. Furthermore, clinical and experimental studies revealed that IUGR is associated with a significantly higher incidence of metabolic, renal and cardiovascular diseases (CVD) later in life. One hypothesis for the higher risk of CVD after IUGR postulates that IUGR induces metabolic alterations that then lead to CVD.

This minireview focuses on recent studies which demonstrate that IUGR is followed by early primary cardiovascular alterations which may directly progress to CVD later in life.

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Title: Intrauterine growth restriction - impact on cardiovascular diseases later in life
Authors: Carlos Menendez-Castro
Wolfgang Rascher
Andrea Hartner
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: Molecular and Cellular Pediatrics / Issue 1/2018
Electronic ISSN: 2194-7791
DOI: https://doi.org/10.1186/s40348-018-0082-5

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