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Clinical and Translational Allergy
Published in: Clinical and Translational Allergy 1/2019

Open Access 01-12-2019 | Omalizumab | Review

Highlights and recent developments in skin allergy and related diseases in EAACI journals (2018)

Authors: C. A. Akdis, J. Bousquet, C. E. Grattan, P. A. Eigenmann, K. Hoffmann-Sommergruber, I. Agache, M. Jutel

Published in: Clinical and Translational Allergy | Issue 1/2019

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Abstract

The European Academy of Allergy and Clinical Immunology (EAACI) supports three journals: Allergy, Paediatric Allergy and Immunology as well as Clinical and Translational Allergy. The major goals of EAACI include (i) supporting health promotion in which the prevention of allergy and asthma plays a critical role and (ii) disseminating the knowledge of allergy to all stakeholders including the EAACI junior members. Substantial progress was made in 2018 in the identification of basic mechanisms of atopic dermatitis and urticaria and the translation of these mechanisms into clinics. Many large epidemiologic studies and meta-analyses have been the highlights of the last year.
Literature
1.
Bousquet J, Grattan C, Bieber T, Matricardi P, Simon HU, Wahn U, et al. Prediction and prevention of allergy and asthma in EAACI journals (2016). Clin Transl Allergy. 2017;7:46.PubMedPubMedCentralCrossRef
2.
Wahn U, Matricardi PM, Bieber T, Bousquet J, Grattan C, Simon HU, et al. Food allergy in EAACI journals (2016). Pediatr Allergy Immunol. 2017;28(8):825–30.PubMedCrossRef
3.
Bousquet J, Akdis CA, Grattan C, Eigenmann PA, Hoffmann-Sommergruber K, Hellings PW, et al. Highlights and recent developments in airway diseases in EAACI journals (2017). Clin Transl Allergy. 2018;8:49.PubMedPubMedCentralCrossRef
4.
Furue M, Yamamura K, Kido-Nakahara M, Nakahara T, Fukui Y. Emerging role of interleukin-31 and interleukin-31 receptor in pruritus in atopic dermatitis. Allergy. 2018;73(1):29–36.PubMedCrossRef
5.
Iwamoto K, Numm TJ, Koch S, Herrmann N, Leib N, Bieber T. Langerhans and inflammatory dendritic epidermal cells in atopic dermatitis are tolerized toward TLR2 activation. Allergy. 2018;73(11):2205–13.PubMedCrossRef
6.
Mitamura Y, Nunomura S, Nanri Y, Ogawa M, Yoshihara T, Masuoka M, et al. The IL-13/periostin/IL-24 pathway causes epidermal barrier dysfunction in allergic skin inflammation. Allergy. 2018;73(9):1881–91.PubMedCrossRef
7.
Nakahara T, Kido-Nakahara M, Ohno F, Ulzii D, Chiba T, Tsuji G, et al. The pruritogenic mediator endothelin-1 shifts the dendritic cell-T-cell response toward Th17/Th1 polarization. Allergy. 2018;73(2):511–5.PubMedCrossRef
8.
Wedman PA, Aladhami A, Chumanevich AP, Fuseler JW, Oskeritzian CA. Mast cells and sphingosine-1-phosphate underlie prelesional remodeling in a mouse model of eczema. Allergy. 2018;73(2):405–15.PubMedCrossRef
9.
Matsuo Y, Yanase Y, Irifuku R, Takahagi S, Mihara S, Ishii K, et al. Neuromedin U directly induces degranulation of skin mast cells, presumably via MRGPRX2. Allergy. 2018;73(11):2256–60.PubMedCrossRef
10.
Noh SR, Kim JS, Kim EH, Jeon BH, Kim JH, Kim YM, et al. Spectrum of susceptibility to air quality and weather in individual children with atopic dermatitis. Pediatr Allergy Immunol. 2019;30(2):179–87.PubMedCrossRef
11.
Sargsyan A, Gupta J, Ghosh D. Association of severe atopic dermatitis with month of birth in armenian pediatric patients. Pediatr Allergy Immunol. 2018;29(6):655–6.PubMedCrossRef
12.
Barbarot S, Auziere S, Gadkari A, Girolomoni G, Puig L, Simpson EL, et al. Epidemiology of atopic dermatitis in adults: results from an international survey. Allergy. 2018;73(6):1284–93.PubMedCrossRef
13.
Lødrup Carlsen KC, Rehbinder EM, Skjerven HO, Carlsen MH, Fatnes TA, Fugelli P, et al. Preventing atopic dermatitis and ALLergies in children—the PreventADALL study. Allergy. 2018;73(10):2063–70.PubMedCrossRef
14.
Gerlich J, Benecke N, Peters-Weist AS, Heinrich S, Roller D, Genuneit J, et al. Pregnancy and perinatal conditions and atopic disease prevalence in childhood and adulthood. Allergy. 2018;73(5):1064–74.PubMedCrossRef
15.
Abuabara K, Yu AM, Okhovat JP, Allen IE, Langan SM. The prevalence of atopic dermatitis beyond childhood: a systematic review and meta-analysis of longitudinal studies. Allergy. 2018;73(3):696–704.PubMedCrossRef
16.
Thyssen JP, Andersen YMF, Zhang H, Gislason G, Skov L, Egeberg A. Incidence of pediatric atopic dermatitis following thymectomy: a Danish register study. Allergy. 2018;73(8):1741–3.PubMedCrossRef
17.
Lee JY, Kim M, Yang HK, Kim HM, Cho J, Kim YM, et al. Reliability and validity of the Atopic Dermatitis Symptom Score (ADSS). Pediatr Allergy Immunol. 2018;29(3):290–5.PubMedCrossRef
18.
Vakharia PP, Chopra R, Sacotte R, Patel N, Immaneni S, White T, et al. Validation of patient-reported global severity of atopic dermatitis in adults. Allergy. 2018;73(2):451–8.PubMedCrossRef
19.
Andersen YMF, Egeberg A, Hamann CR, Skov L, Gislason GH, Skaaby T, et al. Poor agreement in questionnaire-based diagnostic criteria for adult atopic dermatitis is a challenge when examining cardiovascular comorbidity. Allergy. 2018;73(4):923–31.PubMedCrossRef
20.
Hu JM, Lin CS, Chen SJ, Chen CY, Lin CL, Kao CH. Association between obstructive sleep apnea and atopic dermatitis in children: a nationwide, population-based cohort study. Pediatr Allergy Immunol. 2018;29(3):260–6.PubMedCrossRef
21.
Thyssen JP, Hamann CR, Linneberg A, Dantoft TM, Skov L, Gislason GH, et al. Atopic dermatitis is associated with anxiety, depression, and suicidal ideation, but not with psychiatric hospitalization or suicide. Allergy. 2018;73(1):214–20.PubMedCrossRef
22.
Schmitt J, Buske-Kirschbaum A, Tesch F, Trikojat K, Stephan V, Abraham S, et al. Increased attention-deficit/hyperactivity symptoms in atopic dermatitis are associated with history of antihistamine use. Allergy. 2018;73(3):615–26.PubMedCrossRef
23.
Thostesen LM, Kjaergaard J, Pihl GT, Birk NM, Nissen TN, Aaby P, et al. Neonatal BCG vaccination and atopic dermatitis before 13 months of age: a randomized clinical trial. Allergy. 2018;73(2):498–504.PubMedCrossRef
24.
Baek JO, Lee JR, Roh JY, Jung Y. Oral tolerance modulates the skin transcriptome in mice with induced atopic dermatitis. Allergy. 2018;73(4):962–6.PubMedCrossRef
25.
Taghavi Ardakani A, Farrehi M, Sharif MR, Ostadmohammadi V, Mirhosseini N, Kheirkhah D, et al. The effects of melatonin administration on disease severity and sleep quality in children with atopic dermatitis: a randomized, double-blinded, placebo-controlled trial. Pediatr Allergy Immunol. 2018;29(8):834–40.PubMedCrossRef
26.
Shin JU, Kim SH, Noh JY, Kim JH, Kim HR, Jeong KY, et al. Allergen-specific immunotherapy induces regulatory T cells in an atopic dermatitis mouse model. Allergy. 2018;73(9):1801–11.PubMedCrossRef
27.
Sah SK, Agrahari G, Nguyen CT, Kim Y-S, Kang K-S, Kim T-Y. Enhanced therapeutic effects of human mesenchymal stem cells transduced with superoxide dismutase 3 in a murine atopic dermatitis-like skin inflammation model. Allergy. 2018;73(12):2364–76.PubMedCrossRef
28.
Yu J, Liu X, Li Y, Meng S, Wu F, Yan B, et al. Maternal exposure to farming environment protects offspring against allergic diseases by modulating the neonatal TLR-Tregs-Th axis. Clin Transl Allergy. 2018;8:34.PubMedPubMedCentralCrossRef
29.
30.
Napolitano M, Gallo R, Donnarumma M, Patruno C. Salt-dependent aquagenic urticaria in children: report of two cases. Pediatr Allergy Immunol. 2018;29(3):324–6.PubMedCrossRef
31.
Napolitano M, Patruno C. Chronic urticaria can be caused by cancer and resolves with its cure. Allergy. 2018;73(8):1750–1.PubMedCrossRef
32.
Larenas-Linnemann D, Saini SS, Azamar-Jácome AA, Jensen-Jarolim E, Maurer M. Very rarely chronic urticaria can be caused by cancer and if so, resolves with its cure. Allergy. 2018;73(9):1925–6.PubMedCrossRef
33.
Yon DK, Cho YS, Ha EK, Jee HM, Song JY, Jung YH, et al. Exposure to phthalates is associated with acute urticaria in children. Pediatr Allergy Immunol. 2018;29(6):657–60.PubMedCrossRef
34.
Altrichter S, Hawro T, Liedtke M, Holtappels G, Bachert C, Skov PS, et al. In chronic spontaneous urticaria, IgE against staphylococcal enterotoxins is common and functional. Allergy. 2018;73(7):1497–504.PubMedCrossRef
35.
Kolkhir P, Altrichter S, Hawro T, Maurer M. C-reactive protein is linked to disease activity, impact, and response to treatment in patients with chronic spontaneous urticaria. Allergy. 2018;73(4):940–8.PubMedCrossRef
36.
Tuchinda P, Kulthanan K, Chularojanamontri L, Arunkajohnsak S, Sriussadaporn S. Relationship between vitamin D and chronic spontaneous urticaria: a systematic review. Clin Transl Allergy. 2018;8:51.PubMedPubMedCentralCrossRef
37.
Balp MM, Weller K, Carboni V, Chirilov A, Papavassilis C, Severin T, et al. Prevalence and clinical characteristics of chronic spontaneous urticaria in pediatric patients. Pediatr Allergy Immunol. 2018;29(6):630–6.PubMedCrossRef
38.
Cornillier H, Giraudeau B, Munck S, Hacard F, Jonville-Bera AP, d’Acremont G, et al. Chronic spontaneous urticaria in children—a systematic review on interventions and comorbidities. Pediatr Allergy Immunol. 2018;29(3):303–10.PubMedCrossRef
39.
Sussman G, Abuzakouk M, Berard F, Canonica W, Oude Elberink H, Gimenez-Arnau A, et al. Angioedema in chronic spontaneous urticaria is under diagnosed and has a substantial impact: analyses from ASSURE-CSU. Allergy. 2018;73(8):1724–34.PubMedCrossRef
40.
Maurer M, Magerl M, Ansotegui I, Aygören-Pürsün E, Betschel S, Bork K, et al. The international WAO/EAACI guideline for the management of hereditary angioedema—the 2017 revision and update. Allergy. 2018;73(8):1575–96.PubMedCrossRef
41.
Riedl MA, Aygören-Pürsün E, Baker J, Farkas H, Anderson J, Bernstein JA, et al. Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: the OPuS-2 study. Allergy. 2018;73(9):1871–80.PubMedCrossRef
42.
Veszeli N, Kohalmi KV, Kajdacsi E, Gulyas D, Temesszentandrasi G, Cervenak L, et al. Complete kinetic follow-up of symptoms and complement parameters during a hereditary angioedema attack. Allergy. 2018;73(2):516–20.PubMedCrossRef
43.
Bork K, Wulff K, Steinmüller-Magin L, Brænne I, Staubach-Renz P, Witzke G, et al. Hereditary angioedema with a mutation in the plasminogen gene. Allergy. 2018;73(2):442–50.PubMedCrossRef
44.
Dressler C, Rosumeck S, Werner RN, Magerl M, Metz M, Maurer M, et al. Executive summary of the methods report for ‘The EAACI/GA(2) LEN/EDF/WAO Guideline for the Definition, Classification, Diagnosis and Management of Urticaria. The 2017 Revision and Update’. Allergy. 2018;73(5):1145–6.PubMedCrossRef
45.
Zuberbier T, Aberer W, Asero R, Abdul Latiff AH, Baker D, Ballmer-Weber B, et al. The EAACI/GA(2)LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. Allergy. 2018;73(7):1393–414.PubMedCrossRef
46.
Zuberbier T, Bernstein JA. A comparison of the United States and International Perspective on Chronic Urticaria Guidelines. J Allergy Clin Immunol Pract. 2018;6(4):1144–51.PubMedCrossRef
47.
Hawro T, Ohanyan T, Schoepke N, Metz M, Peveling-Oberhag A, Staubach P, et al. Comparison and interpretability of the available urticaria activity scores. Allergy. 2018;73(1):251–5.PubMedCrossRef
48.
Lin CH, Hung PH, Hu HY, Chung CJ, Chen TH, Hung KY. Clinically diagnosed urticaria and risk of systemic lupus erythematosus in children: a nationwide population-based case-control study. Pediatr Allergy Immunol. 2018;29(7):732–9.PubMedCrossRef
49.
Kolkhir P, Pereverzina N, Olisova O, Maurer M. Comorbidity of viral hepatitis and chronic spontaneous urticaria: a systematic review. Allergy. 2018;73(10):1946–53.PubMedCrossRef
50.
Weller K, Church MK, Hawro T, Altrichter S, Labeaga L, Magerl M, et al. Updosing of bilastine is effective in moderate to severe chronic spontaneous urticaria: a real-life study. Allergy. 2018;73(10):2073–5.PubMedCrossRef
51.
Staubach P, Metz M, Chapman-Rothe N, Sieder C, Brautigam M, Maurer M, et al. Omalizumab rapidly improves angioedema-related quality of life in adult patients with chronic spontaneous urticaria: X-ACT study data. Allergy. 2018;73(3):576–84.PubMedCrossRef
52.
Caballero T, Zanichelli A, Aberer W, Maurer M, Longhurst HJ, Bouillet L, et al. Effectiveness of icatibant for treatment of hereditary angioedema attacks is not affected by body weight: findings from the Icatibant Outcome Survey, a cohort observational study. Clin Transl Allergy. 2018;8:11.PubMedPubMedCentralCrossRef
53.
de Brito M, Huebner G, Murrell D, Bullpitt P, Hartmann K. Normocomplementaemic urticarial vasculitis: effective treatment with omalizumab. Clin Transl Allergy. 2018;8:37.PubMedPubMedCentralCrossRef
54.
Cugno M, Asero R, Ferrucci S, Lorini M, Carbonelli V, Tedeschi A, et al. Elevated IgE to tissue factor and thyroglobulin are abated by omalizumab in chronic spontaneous urticaria. Allergy. 2018;73(12):2408–11.PubMedCrossRef
55.
Weller K, Ohanyan T, Hawro T, Ellrich A, Sussman G, Koplowitz J, et al. Total IgE levels are linked to the response of chronic spontaneous urticaria patients to omalizumab. Allergy. 2018;73(12):2406–8.PubMedCrossRef
56.
Ertas R, Ozyurt K, Atasoy M, Hawro T, Maurer M. The clinical response to omalizumab in chronic spontaneous urticaria patients is linked to and predicted by IgE levels and their change. Allergy. 2018;73(3):705–12.PubMedCrossRef
57.
Asero R. Efficacy of omalizumab 150 mg/month as a maintenance dose in patients with severe chronic spontaneous urticaria showing a prompt and complete response to the drug. Allergy. 2018;73(11):2242–4.PubMedCrossRef
58.
Eapen A, Kloepfer KM. Serum sickness-like reaction in a pediatric patient using omalizumab for chronic spontaneous urticaria. Pediatr Allergy Immunol. 2018;29(4):449–50.PubMedCrossRef
Metadata
Title
Highlights and recent developments in skin allergy and related diseases in EAACI journals (2018)
Authors
C. A. Akdis
J. Bousquet
C. E. Grattan
P. A. Eigenmann
K. Hoffmann-Sommergruber
I. Agache
M. Jutel
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Clinical and Translational Allergy / Issue 1/2019
Electronic ISSN: 2045-7022
DOI
https://doi.org/10.1186/s13601-019-0299-y

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