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01-12-2021 | Hypertension | Letter

Is urinary Na/K ratio an independent indicator associated with current hypertension and RA disease activity or just an artifact? Comment on article by Minamino H et al

Author: Reza Rastmanesh

Published in: Arthritis Research & Therapy | Issue 1/2021

Excerpt

I read with interest the article by Minamino et al. [1]. I would like to clarify some of the significant findings and suggest re-analysis needed to validate their core conclusion. …

Minamino H, Katsushima M, Hashimoto M, Fujita Y, Yoshida T, Ikeda K, et al. Urinary sodium-to-potassium ratio associates with hypertension and current disease activity in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2021;23(1):96.CrossRef

Kawasaki T, Delea CS, Bartter FC, Smith H. The effect of high-sodium and low-sodium intakes on blood pressure and other related variables in human subjects with idiopathic hypertension. Am J Med. 1978;64(2):193–8. https://doi.org/10.1016/0002-9343(78)90045-1.CrossRefPubMed

Morgan T, Teow BH, Myers J. The role of potassium in control of blood pressure. Drugs. 1984;28(Suppl 1):188–95.CrossRef

Goto A, Yamada K, Hazama H, Uehara Y, Atarashi K, Hirata Y, et al. Ouabainlike compound in hypertension associated with ectopic corticotropin syndrome. Hypertension. 1996;28(3):421–5.CrossRef

Tasevska N, Runswick SA, Bingham SA. Urinary potassium is as reliable as urinary nitrogen for use as a recovery biomarker in dietary studies of free living individuals. J Nutr. 2006;136(5):1334–40.CrossRef

Mercado CI, Cogswell ME, Valderrama AL, Wang CY, Loria CM, Moshfegh AJ, et al. Difference between 24-h diet recall and urine excretion for assessing population sodium and potassium intake in adults aged 18-39 y. Am J Clin Nutr. 2015;101(2):376–86. https://doi.org/10.3945/ajcn.113.081604.CrossRefPubMed

Okuda N, Okayama A, Miura K, Yoshita K, Miyagawa N, Saitoh S, et al. Food sources of dietary potassium in the adult Japanese population: the International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP). Nutrients. 2020;12(3):2–10.

Stamler J, Chan Q, Daviglus ML, Dyer AR, Van HL, Garside DB, et al. Relation of dietary sodium (Salt) to blood pressure and its possible modulation by other dietary factors: the INTERMAP study. Hypertension. 2018;71(4):631–7. https://doi.org/10.1161/HYPERTENSIONAHA.117.09928.CrossRefPubMed

Hoorn EJ, Gritter M, Cuevas CA, Fenton RA. Regulation of the renal NaCl cotransporter and its role in potassium homeostasis. Physiol Rev. 2020;100(1):321–56. https://doi.org/10.1152/physrev.00044.2018.CrossRefPubMed

10.

Tanaka T, Okamura T, Miura K, Kadowaki T, Ueshima H, Nakagawa H, et al. A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen. J Hum. Hypertens. 2002;16(2):97–103. https://doi.org/10.1038/sj.jhh.1001307.CrossRefPubMed

11.

Dong J, Zhao X, Dong H, Yan Y, Mi J. Can spot urine measurement be a substitute for 24-hour urine measurement to estimate sodium intake in adolescents? Pediatr. Investig. 2021;5(1):12–20. https://doi.org/10.1002/ped4.12243.CrossRefPubMedPubMedCentral

12.

Dzau VJ, Brody T, Ellison KE, Pratt RE, Ingelfinger JR. Tissue-specific regulation of renin expression in the mouse. Hypertension. 1987;9(6 Pt 2):III36–41.PubMed

13.

Braz NFT, Pinto MRC, Vieira ELM, Souza AJ, Teixeira AL, Simoes-E-Silva AC, et al. Renin-angiotensin system molecules are associated with subclinical atherosclerosis and disease activity in rheumatoid arthritis. Mod. Rheumatol. 2021;31(1):119–26. https://doi.org/10.1080/14397595.2020.1740418.CrossRefPubMed

14.

Wu Y, Li M, Zeng J, Feng Z, Yang J, Shen B, et al. Differential expression of renin-angiotensin system-related components in patients with rheumatoid arthritis and osteoarthritis. Am. J Med Sci. 2020;359(1):17–26. https://doi.org/10.1016/j.amjms.2019.10.014.CrossRefPubMed

Title: Is urinary Na/K ratio an independent indicator associated with current hypertension and RA disease activity or just an artifact? Comment on article by Minamino H et al
Author: Reza Rastmanesh
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Hypertension
Hypertension
Published in: Arthritis Research & Therapy / Issue 1/2021
Electronic ISSN: 1478-6362
DOI: https://doi.org/10.1186/s13075-021-02571-2

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