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Open Access 01-12-2017 | Editorial

How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis?

Author: M. Shankar-Hari

Published in: Critical Care | Issue 1/2017

Abstract

Sepsis results in complex alterations to the immune system. Our understanding of how these alterations in immune responses could help characterize extreme immune phenotypes, identify biomarkers with the ability to stratify patients for therapeutic interventions, surrogates in the causal pathway of clinical end-points, and treatable traits are still rudimentary. A methodologically rigorous, consensus-based approach should enrich sepsis immune subpopulations to increase the probability of successful trials.

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Title: How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis?
Author: M. Shankar-Hari
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Critical Care / Issue 1/2017
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-017-1715-0

ACC 2024 Congress

Springer Medicine

How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis?

Abstract

ACC 2024 Congress

Springer Medicine

Abstract

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