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Open Access 01-12-2017 | Letter

Plasma concentrations of caspofungin in a critically ill patient with morbid obesity

Authors: Rafael Ferriols-Lisart, Gerardo Aguilar, Alejandro Pérez-Pitarch, Jaume Puig, Carlos Ezquer-Garín, Manuel Alós

Published in: Critical Care | Issue 1/2017

Excerpt

The aim of the study was to describe the pharmacokinetic behaviour of caspofungin in a critically ill patient with morbid obesity who received doses of caspofungin higher than labelled doses. …

Pérez-Pitarch A, Ferriols-Lisart R, Aguilar G, et al. Dosing of caspofungin based on a pharmacokinetic/pharmacodynamic index for the treatment of invasive fungal infections in critically ill patients on continuous venovenous haemodiafiltration. Int J Antimicrob Agents. 2017. doi:10.1016/j.ijantimicag.2017.05.013.PubMed

Aguilar G, Ferriols R, Lozano A, et al. Optimal doses of caspofungin during continuous venovenous hemodiafiltration in critically ill patients. Crit Care. 2017;21:17.CrossRefPubMedPubMedCentral

Song JC, Stevens DA. Caspofungin: pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes. Crit Rev Microbiol. 2016;42(5):813–46. doi:10.3109/1040841X.2015.1068271.CrossRefPubMed

Payne K, Hall R. Dosing of antifungal agents in obese people. Expert Rev Anti Infect Ther. 2016;14(2):257–61. doi:10.1586/14787210.2016.1128822.CrossRefPubMed

Lahmer T, Schnappauf C, Messer M, et al. Influence of echinocandin administration on hemodynamic parameters in medical intensive care unit patients: a single center prospective study. Infection. 2015;43(6):723–7. doi:10.1007/s15010-015-0828-0.CrossRefPubMed

Title: Plasma concentrations of caspofungin in a critically ill patient with morbid obesity
Authors: Rafael Ferriols-Lisart
Gerardo Aguilar
Alejandro Pérez-Pitarch
Jaume Puig
Carlos Ezquer-Garín
Manuel Alós
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Critical Care / Issue 1/2017
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-017-1774-2

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Plasma concentrations of caspofungin in a critically ill patient with morbid obesity

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