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Journal of Ovarian Research

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Open Access 01-12-2017 | Research

Prognostic analysis for Chinese patients with stage I ovarian endometrioid carcinoma

Authors: Yu Zhao, Shu Wang, Yi-Min Qu, Yu-Ting Ji, Keng Shen, Jing He Lang

Published in: Journal of Ovarian Research | Issue 1/2017

Abstract

Background

This study aimed to identify the clinical and pathological characteristics and the possible prognostic factors for Chinese patients with early-stage ovarian endometrioid carcinoma.

Methods

The present study reviewed the medical records of patients who received initial treatment and a postoperative pathological diagnosis of ovarian endometrioid carcinoma at our center. In all, 78 patients had stage I ovarian endometrioid carcinoma.

Results

In this series, the 5-year overall survival rate and 5-year disease-free survival (DFS) rates of patients with stage I ovarian endometrioid carcinoma was 98.7% and 87.2%, respectively. Univariate analysis showed the factors that influence the DFS rates include menopausal status, FIGO stage, histological grade, lymphadenectomy, cytology of ascites. Multivariate analysis showed that grade 3 and lymphadenectomy were the independent prognostic factors of DFS for Stage I ovarian endometrioid carcinoma (P = 0.0259, 0.0276 respectively). However, the coexisting endometriosis, concomitant endometrial disorders, dissection of para-aortic lymph node and more courses of thermotherapy had no influence on DFS. Besides, it was found that 19.3% of patients in this series had synchronous early stage and well-to-moderate differentiated endometrial carcinoma.

Conclusions

Grade 3 and lymphadenectomy were indicated as the independent factors of DFS for stage I patients with ovarian endometrioid carcinoma. The endometrial changes should be considered seriously when fertility-sparing surgery was planned.

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Title: Prognostic analysis for Chinese patients with stage I ovarian endometrioid carcinoma
Authors: Yu Zhao
Shu Wang
Yi-Min Qu
Yu-Ting Ji
Keng Shen
Jing He Lang
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Journal of Ovarian Research / Issue 1/2017
Electronic ISSN: 1757-2215
DOI: https://doi.org/10.1186/s13048-017-0361-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Prognostic analysis for Chinese patients with stage I ovarian endometrioid carcinoma

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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