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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2021

01-12-2021 | Chondrosarcoma | Case report

An unusual example of hereditary multiple exostoses: a case report and review of the literature

Authors: Rebecca Chilvers, James A. Gallagher, Nathan Jeffery, Alistair P. Bond

Published in: BMC Musculoskeletal Disorders | Issue 1/2021

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Abstract

Background

Hereditary multiple exostoses (HME) is a rare skeletal disorder characterised by a widespread.
distribution of osteochondromas originating from the metaphyses of long bones.

Case presentation

This case study examines a 55-year-old male cadaver bequeathed to the University of Liverpool who suffered from HME, thus providing an exceptionally rare opportunity to examine the anatomical changes associated with this condition.

Conclusions

Findings from imaging and dissection indicated that this was a severe case of HME in terms of the quantity and distribution of the osteochondromas and the number of synostoses present. In addition, the existence of enchondromas and the appearance of gaps within the trabeculae of affected bones make this a remarkable case. This study provides a comprehensive overview of the morbidity of the disease as well as adding to the growing evidence that diseases concerning benign cartilaginous tumours may be part of a spectrum rather than distinct entities.
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Metadata
Title
An unusual example of hereditary multiple exostoses: a case report and review of the literature
Authors
Rebecca Chilvers
James A. Gallagher
Nathan Jeffery
Alistair P. Bond
Publication date
01-12-2021
Publisher
BioMed Central
Keyword
Chondrosarcoma
Published in
BMC Musculoskeletal Disorders / Issue 1/2021
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-021-03967-6

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