Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Skeletal Radiology
Published in: Skeletal Radiology 5/2015

01-05-2015 | Case Report

Regression of an enchondroma: a case report and proposed etiology

Authors: Anirban Sensarma, John E. Madewell, Jeanne M. Meis, Rajendra Kumar, Patrick P. Lin, Behrang Amini

Published in: Skeletal Radiology | Issue 5/2015

Login to get access

Abstract

Enchondromas are common benign bone lesions that are found in the medullary cavity of tubular bones, usually at the metaphysis. Regression is highly unusual, and loss of matrix mineralization in an existing enchondroma should prompt investigation for malignant transformation. We present the case of a 50-year-old woman with an enchondroma of the proximal humeral metadiaphysis, which underwent loss of matrix mineralization that corresponded to replacement with marrow fat on MRI. This transformation of the cartilage tumor matrix into normal bone marrow may occur in a process similar to that seen with endochondral ossification.
Literature
1.
Lucas DR, Bridge JA. Chondromas: enchondroma, periosteal chondroma, and enchondromatosis. In: Fletcher CDM, Unni KK, Mertens F, editors. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002. p. 237–40.
2.
Brien EW, Mirra JM, Kerr R. Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. I. The intramedullary cartilage tumors. Skelet Radiol. 1997;26(6):325–53.CrossRef
3.
4.
Murphey MD, Flemming DJ, Boyea SR, Bojescul JA, Sweet DE, Temple HT. Enchondroma versus chondrosarcoma in the appendicular skeleton: differentiating features. Radiographics. 1998;18(5):1213–37.CrossRefPubMed
5.
Baruchin A, Rosenberg L, Itzchaki M. Spontaneous restitution ad integrum of a fractured enchondroma in a finger. Int J Tissue React. 1981;3(1):17–20.PubMed
6.
Miyawaki T, Kinoshita Y, Iizuka T. A case of Ollier's disease of the hand. Ann Plast Surg. 1997;38(1):77–80.CrossRefPubMed
7.
Anshu BY, Nalinimohan C, Gangane N. Cytodiagnosis of Ollier's disease: a case report. Diagn Cytopathol. 2009;37(7):513–5.CrossRef
8.
9.
Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dev Cell. 2002;2(4):389–406.CrossRefPubMed
10.
Ortega N, Wang K, Ferrara N, Werb Z, Vu TH. Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formation. Dis Model Mech. 2010;3(3–4):224–35.CrossRefPubMedCentralPubMed
11.
Dirckx N, Van Hul M, Maes C. Osteoblast recruitment to sites of bone formation in skeletal development, homeostasis, and regeneration. Birth Defects Res Part C Embryo Today: Reviews. 2013;99(3):170–91.
Metadata
Title
Regression of an enchondroma: a case report and proposed etiology
Authors
Anirban Sensarma
John E. Madewell
Jeanne M. Meis
Rajendra Kumar
Patrick P. Lin
Behrang Amini
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 5/2015
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-014-2032-1

Other articles of this Issue 5/2015

Skeletal Radiology 5/2015 Go to the issue

Scientific Article

Peripheral nerve MRI: precision and reproducibility of T2*-derived measurements at 3.0-T

Case Report

Sclerotic multiple myeloma with an unusual sunburst periosteal reaction occurring in the sternum

Scientific Article

Frequency, imaging findings, risk factors, and long-term sequelae of distal clavicular osteolysis in young patients

Scientific Article

Differentiating os acromiale from normally developing acromial ossification centers using magnetic resonance imaging

Scientific Article

Leukocyte esterase analysis in the diagnosis of joint infection: Can we make a diagnosis using a simple urine dipstick?

Technical Report

CT-guided radiofrequency ablation of osteoid osteoma using a novel battery-powered drill