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Published in: BMC Infectious Diseases 1/2022

Open Access 01-12-2022 | Leishmania | Research

A machine learning-based system for detecting leishmaniasis in microscopic images

Authors: Mojtaba Zare, Hossein Akbarialiabad, Hossein Parsaei, Qasem Asgari, Ali Alinejad, Mohammad Saleh Bahreini, Seyed Hossein Hosseini, Mohsen Ghofrani-Jahromi, Reza Shahriarirad, Yalda Amirmoezzi, Sepehr Shahriarirad, Ali Zeighami, Gholamreza Abdollahifard

Published in: BMC Infectious Diseases | Issue 1/2022

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Abstract

Background

Leishmaniasis, a disease caused by a protozoan, causes numerous deaths in humans each year. After malaria, leishmaniasis is known to be the deadliest parasitic disease globally. Direct visual detection of leishmania parasite through microscopy is the frequent method for diagnosis of this disease. However, this method is time-consuming and subject to errors. This study was aimed to develop an artificial intelligence-based algorithm for automatic diagnosis of leishmaniasis.

Methods

We used the Viola-Jones algorithm to develop a leishmania parasite detection system. The algorithm includes three procedures: feature extraction, integral image creation, and classification. Haar-like features are used as features. An integral image was used to represent an abstract of the image that significantly speeds up the algorithm. The adaBoost technique was used to select the discriminate features and to train the classifier.

Results

A 65% recall and 50% precision was concluded in the detection of macrophages infected with the leishmania parasite. Also, these numbers were 52% and 71%, respectively, related to amastigotes outside of macrophages.

Conclusion

The developed system is accurate, fast, easy to use, and cost-effective. Therefore, artificial intelligence might be used as an alternative for the current leishmanial diagnosis methods.
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Metadata
Title
A machine learning-based system for detecting leishmaniasis in microscopic images
Authors
Mojtaba Zare
Hossein Akbarialiabad
Hossein Parsaei
Qasem Asgari
Ali Alinejad
Mohammad Saleh Bahreini
Seyed Hossein Hosseini
Mohsen Ghofrani-Jahromi
Reza Shahriarirad
Yalda Amirmoezzi
Sepehr Shahriarirad
Ali Zeighami
Gholamreza Abdollahifard
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-022-07029-7

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