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Published in: BMC Infectious Diseases 1/2020

Open Access 01-12-2020 | Tick-Borne Encephalitis | Case report

Viscerotropic disease and acute uveitis following yellow fever vaccination: a case report

Authors: Lev Volkov, Gilda Grard, Pierre-Edouard Bollaert, Guillaume A. Durand, Aurélie Cravoisy, Marie Conrad, Lionel Nace, Guilhem Courte, Rémy Marnai, Isabelle Leparc-Goffart, Sébastien Gibot

Published in: BMC Infectious Diseases | Issue 1/2020

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Abstract

Background

Yellow fever vaccine exists for over 80 years and is considered to be relatively safe. However, in rare cases it can produce serious neurotropic and viscerotropic complications. We report a case of a patient who presented both viscerotropic and neurological manifestations after yellow fever vaccination.

Case presentation

We describe the case of a 37 years old man who developed after the yellow fever vaccination a yellow fever vaccine-associated viscerotropic disease followed by acute uveitis. Prolonged detection of yellow fever RNA in blood and urine was consistent with yellow fever vaccine-associated adverse event. The final outcome was good, although with persistent fatigue over a few months.

Conclusions

Even if the yellow fever vaccine is relatively safe, physicians should be aware of its possible serious adverse effects.
Literature
1.
go back to reference Staples JE, Gershman M, Fischer M, Centers for Disease Control and Prevention (CDC). Yellow fever vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep Morb Mortal Wkly Rep Recomm Rep. 2010;59(RR-7):1–27. Staples JE, Gershman M, Fischer M, Centers for Disease Control and Prevention (CDC). Yellow fever vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep Morb Mortal Wkly Rep Recomm Rep. 2010;59(RR-7):1–27.
3.
go back to reference Theiler M, Smith HH. The use of yellow fever virus modified by in vitro cultivation for human immunization. J Exp Med. 1937;65(6):787–800.CrossRef Theiler M, Smith HH. The use of yellow fever virus modified by in vitro cultivation for human immunization. J Exp Med. 1937;65(6):787–800.CrossRef
13.
go back to reference Martin M, et al. Fever and multisystem organ failure associated with 17D-204 yellow fever vaccination: a report of four cases. Lancet Lond Engl. 2001;358(9276):98–104.CrossRef Martin M, et al. Fever and multisystem organ failure associated with 17D-204 yellow fever vaccination: a report of four cases. Lancet Lond Engl. 2001;358(9276):98–104.CrossRef
Metadata
Title
Viscerotropic disease and acute uveitis following yellow fever vaccination: a case report
Authors
Lev Volkov
Gilda Grard
Pierre-Edouard Bollaert
Guillaume A. Durand
Aurélie Cravoisy
Marie Conrad
Lionel Nace
Guilhem Courte
Rémy Marnai
Isabelle Leparc-Goffart
Sébastien Gibot
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2020
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-020-4838-x

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