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Published in: BMC Infectious Diseases 1/2020

01-12-2020 | Meningococcus | Case report

Nocardia farcinica as a cause of chronic meningitis – case report

Authors: Anna Moniuszko-Malinowska, Piotr Czupryna, Izabela Swiecicka, Henryk Grześ, Agnieszka Siemieniako, Sambor Grygorczuk, Eugeniusz Tarasów, Sławomir Pancewicz

Published in: BMC Infectious Diseases | Issue 1/2020

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Abstract

Background

Nocardiosis is an uncommon disease caused by aerobic gram-positive bacteria Nocardia spp. Although it is usually an opportunistic infection affecting immunocompromised patients, even one third of cases occur in immunocompetent persons. The aim of the study was to describe the course of chronic meningitis due to Nocardia infection.

Case presentation

A 52-year-old patient, chalk miner, suffered from a chronic meningitis caused by an extremely rare pathogen. The patient’s history was complicated and diagnostic process covered multiple examinations and consultations. Initially Kocuria rosea was cultured, yet after molecular examination the result was verified to Nocardia farcinica. Targeted antibiotic treatment was implemented, which resulted in gradual improvement of patients condition. A full recovery was achieved after one year antibiotic therapy.

Conclusions

1.
Nocardia farcinica is an uncommon but possible cause of chronic meningitis.
 
2.
In the case of a chronic meningitis of unknown origin multiple cerebrospinal fluid cultures should be performed as the identification of pathogen may be crucial for patient’s recovery.
 
3.
In case of unusual culture, such as Kocuria spp. PCR should be performed.
 
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Metadata
Title
Nocardia farcinica as a cause of chronic meningitis – case report
Authors
Anna Moniuszko-Malinowska
Piotr Czupryna
Izabela Swiecicka
Henryk Grześ
Agnieszka Siemieniako
Sambor Grygorczuk
Eugeniusz Tarasów
Sławomir Pancewicz
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2020
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-020-4764-y

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