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BMC Infectious Diseases

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01-12-2020 | Tick | Research article

Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus

Authors: Lingling Mao, Baocheng Deng, Yuhong Liang, Yun Liu, Zijiang Wang, Jie Zhang, Wei Wu, Lei Yu, Wenqing Yao

Published in: BMC Infectious Diseases | Issue 1/2020

Abstract

Background

To analyze and discuss the transmission route of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus (SFTSV).

Method

We performed an epidemiological investigation and a genetic analysis of patients with severe fever with thrombocytopenia syndrome (SFTS) caused by SFTSV, their close contacts and the surrounding population.

Results

We found that all patients had contact with the blood of the first patient. The comparison of gene sequences in the three isolated SFTSV strains showed that the strains were closely related. Six close contacts and nine individuals in the surrounding population were positive for SFTSV IgM antibody.

Conclusion

We suspect that the cluster outbreak was transmitted via blood and that the natural reservoir host of SFTSV exists in the patients’ environment.

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Title: Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus
Authors: Lingling Mao
Baocheng Deng
Yuhong Liang
Yun Liu
Zijiang Wang
Jie Zhang
Wei Wu
Lei Yu
Wenqing Yao
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Tick
Thrombocytopenia
Tick
Published in: BMC Infectious Diseases / Issue 1/2020
Electronic ISSN: 1471-2334
DOI: https://doi.org/10.1186/s12879-020-05072-w

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Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus

Abstract

Background

Method

Results

Conclusion

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Abstract

Background

Method

Results

Conclusion

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