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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2016

Open Access 01-12-2016 | Research article

Co-distribution and co-infection of chikungunya and dengue viruses

Authors: Luis Furuya-Kanamori, Shaohong Liang, Gabriel Milinovich, Ricardo J. Soares Magalhaes, Archie C. A. Clements, Wenbiao Hu, Patricia Brasil, Francesca D. Frentiu, Rebecca Dunning, Laith Yakob

Published in: BMC Infectious Diseases | Issue 1/2016

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Abstract

Background

Chikungunya and dengue infections are spatio-temporally related. The current review aims to determine the geographic limits of chikungunya, dengue and the principal mosquito vectors for both viruses and to synthesise current epidemiological understanding of their co-distribution.

Methods

Three biomedical databases (PubMed, Scopus and Web of Science) were searched from their inception until May 2015 for studies that reported concurrent detection of chikungunya and dengue viruses in the same patient. Additionally, data from WHO, CDC and Healthmap alerts were extracted to create up-to-date global distribution maps for both dengue and chikungunya.

Results

Evidence for chikungunya-dengue co-infection has been found in Angola, Gabon, India, Madagascar, Malaysia, Myanmar, Nigeria, Saint Martin, Singapore, Sri Lanka, Tanzania, Thailand and Yemen; these constitute only 13 out of the 98 countries/territories where both chikungunya and dengue epidemic/endemic transmission have been reported.

Conclusions

Understanding the true extent of chikungunya-dengue co-infection is hampered by current diagnosis largely based on their similar symptoms. Heightened awareness of chikungunya among the public and public health practitioners in the advent of the ongoing outbreak in the Americas can be expected to improve diagnostic rigour. Maps generated from the newly compiled lists of the geographic distribution of both pathogens and vectors represent the current geographical limits of chikungunya and dengue, as well as the countries/territories at risk of future incursion by both viruses. These describe regions of co-endemicity in which lab-based diagnosis of suspected cases is of higher priority.
Appendix
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Metadata
Title
Co-distribution and co-infection of chikungunya and dengue viruses
Authors
Luis Furuya-Kanamori
Shaohong Liang
Gabriel Milinovich
Ricardo J. Soares Magalhaes
Archie C. A. Clements
Wenbiao Hu
Patricia Brasil
Francesca D. Frentiu
Rebecca Dunning
Laith Yakob
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2016
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-016-1417-2

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