Published in:
Open Access
01-12-2019 | Alzheimer's Disease | Case report
FDG-PET in suspected dementia with Lewy bodies: a case report
Authors:
Astrid Melani Suantio, Hian Liang Huang, Cecilia Sze Nga Kwok, Darren Cheng Han Teo, Minh Ha Nguyen
Published in:
BMC Geriatrics
|
Issue 1/2019
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Abstract
Background
Dementia with Lewy bodies (DLB) is still underdiagnosed or mistaken for other types of neurodegenerative diseases. Biomarkers such as 18-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) can be helpful.
Case presentation
A 72-year-old gentleman presented with postural hypotension, hallucination, Parkinsonism and recurrent falls. He also had rapidly progressing cognitive impairment. CT and MRI brain showed atrophy of the frontal lobes with preservation of the hippocampi. FDG-PET was suggestive of DLB. He was subsequently treated with Rivastigmine, with significant improvement of his symptoms.
Conclusion
This case highlights the challenges in diagnosis of an elderly patient with DLB, the use of neuro-imaging as a diagnostic biomarker, the avoidance of the use of antipsychotic and the response to pharmacological treatment with Rivastigmine after a probable diagnosis of DLB.