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Published in: BMC Cardiovascular Disorders 1/2019

Open Access 01-12-2019 | Heart Surgery | Research article

Long-term survival and quality of life in Jehovah’s witnesses after cardiac surgery: a case control study

Authors: Pierre Wauthy, Charalampos Pierrakos, Louis Chebli, Redente Tortora

Published in: BMC Cardiovascular Disorders | Issue 1/2019

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Abstract

Background

We previously analyzed morbidity and mortality in Jehovah’s Witnesses patients after cardiac surgery compared to control population patients. Patients who were Jehovah’s Witnesses were operated in accordance with their philosophical convictions and in respect of their refusal of transfusions. We propose to assess long-term survival and quality of life in the patients of this preliminary study.

Methods

We contacted 31 adult Jehovah’s Witnesses patients who underwent heart surgery at the Brugmann hospital between 1991 and 2012 and compared them to a control population of 62 patients that had no transfusion restriction, and matched them for sex, age at the time of intervention and the type of surgery performed. We compared long-term quality of life in both populations through the MacNew software, a validated instrument to assess quality of life of patients with cardiovascular disease. The long-term survival of patients was analyzed by Kaplan Meier curves.

Results

Long-term quality of life and survival do not appear different between the two groups. Patient evaluation by MacNew software shows comparable physical (p = 0.54), emotional (p = 0.12), social (p = 0.21) and global (p = 0.25) scores between the two populations. The analysis of the actuarial survival curves shows no differences in terms of long-term survival of these patients (p = 0.37).

Conclusions

Cardiac surgery in Jehovah’s Witnesses can be performed with identical long-term quality of life and survival compared to surgery without blood transfusion restriction, if one follows rigorous blood conserving strategies.

Trial registration

NCT03348072. Retrospectively registered 16 November 2017.
Literature
1.
go back to reference Bhaskar B, Jack RK, Mullany D, Fraser J. Comparison of outcome in Jehovah's witness patients in cardiac surgery: an Australian experience. Heart Lung Circ. 2010;19(11):655–9.CrossRef Bhaskar B, Jack RK, Mullany D, Fraser J. Comparison of outcome in Jehovah's witness patients in cardiac surgery: an Australian experience. Heart Lung Circ. 2010;19(11):655–9.CrossRef
2.
go back to reference Marinakis S, Van der Linden P, Tortora R, Massaut J, Pierrakos C, Wauthy P. Outcomes from cardiac surgery in Jehovah's witness patients: experience over twenty-one years. J Cardiothorac Surg. 2016;11(1):67.CrossRef Marinakis S, Van der Linden P, Tortora R, Massaut J, Pierrakos C, Wauthy P. Outcomes from cardiac surgery in Jehovah's witness patients: experience over twenty-one years. J Cardiothorac Surg. 2016;11(1):67.CrossRef
3.
go back to reference Pattakos G, Koch CG, Brizzio ME, Batizy LH, Sabik JF 3rd, Blackstone EH, et al. Outcome of patients who refuse transfusion after cardiac surgery: a natural experiment with severe blood conservation. Arch Intern Med. 2012;172(5):1154–60.PubMed Pattakos G, Koch CG, Brizzio ME, Batizy LH, Sabik JF 3rd, Blackstone EH, et al. Outcome of patients who refuse transfusion after cardiac surgery: a natural experiment with severe blood conservation. Arch Intern Med. 2012;172(5):1154–60.PubMed
4.
go back to reference Stamou SC, White T, Barnett S, Boyce SW, Corso PJ, Lefrak EA. Comparisons of cardiac surgery outcomes in Jehovah's versus non-Jehovah's witnesses. Am J Cardiol. 2006;98(9):1223–5.CrossRef Stamou SC, White T, Barnett S, Boyce SW, Corso PJ, Lefrak EA. Comparisons of cardiac surgery outcomes in Jehovah's versus non-Jehovah's witnesses. Am J Cardiol. 2006;98(9):1223–5.CrossRef
5.
go back to reference Höfer S, Lim L, Guyatt G, Oldridge N. The MacNew heart disease health-related quality of life instrument: a summary. Health Qual Life Outcomes. 2004 Jan 8;2:3.CrossRef Höfer S, Lim L, Guyatt G, Oldridge N. The MacNew heart disease health-related quality of life instrument: a summary. Health Qual Life Outcomes. 2004 Jan 8;2:3.CrossRef
6.
go back to reference Pavy B, Iliou MC, Höfer S, Vergès-Patois B, Corone S, Aeberhard P, et al. Validation of the French version of the MacNew heart disease health-related quality of life questionnaire. Arch Cardiovasc Dis. 2015;108(2):107–17.CrossRef Pavy B, Iliou MC, Höfer S, Vergès-Patois B, Corone S, Aeberhard P, et al. Validation of the French version of the MacNew heart disease health-related quality of life questionnaire. Arch Cardiovasc Dis. 2015;108(2):107–17.CrossRef
7.
go back to reference Gjeilo KH, Stenseth R, Wahba A, Lydersen S, Klepstad P. Long-term health-related quality of life and survival after cardiac surgery: a prospective study. J Thorac Cardiovasc Surg. 2018;156(6):2183–90.CrossRef Gjeilo KH, Stenseth R, Wahba A, Lydersen S, Klepstad P. Long-term health-related quality of life and survival after cardiac surgery: a prospective study. J Thorac Cardiovasc Surg. 2018;156(6):2183–90.CrossRef
8.
go back to reference Verwijmeren L, Noordzij PG, Daeter EJ, van Zaane B, Peelen LM, van Dongen EPA. Preoperative determinants of quality of life a year after coronary artery bypass grafting: a historical cohort study. J Cardiothorac Surg. 2018;13(1):118.CrossRef Verwijmeren L, Noordzij PG, Daeter EJ, van Zaane B, Peelen LM, van Dongen EPA. Preoperative determinants of quality of life a year after coronary artery bypass grafting: a historical cohort study. J Cardiothorac Surg. 2018;13(1):118.CrossRef
9.
go back to reference Barrie K, Cornick A, Debreuil S, Lee E, Hiebert BM, Manji RA, et al. Patients with a prolonged intensive care unit length of stay have decreased health-related quality of life after cardiac surgery. Semin Thorac Cardiovasc Surg. 2019 Spring;31(1):21–31.CrossRef Barrie K, Cornick A, Debreuil S, Lee E, Hiebert BM, Manji RA, et al. Patients with a prolonged intensive care unit length of stay have decreased health-related quality of life after cardiac surgery. Semin Thorac Cardiovasc Surg. 2019 Spring;31(1):21–31.CrossRef
10.
go back to reference Trivedi V, Bleeker H, Kantor N, Visintini S, McIsaac DI, McDonald B. Survival, quality of life, and functional status following prolonged ICU stay in cardiac surgical patients: a systematic review. Crit Care Med. 2019;47(1):e52–63.CrossRef Trivedi V, Bleeker H, Kantor N, Visintini S, McIsaac DI, McDonald B. Survival, quality of life, and functional status following prolonged ICU stay in cardiac surgical patients: a systematic review. Crit Care Med. 2019;47(1):e52–63.CrossRef
11.
go back to reference De Gucht V, Van Elderen T, van der Kamp L, Oldridge N. Quality of life after myocardial infarction: translation and validation of the MacNew questionnaire for a Dutch population. Qual Life Res. 2004;13(8):1483–8.CrossRef De Gucht V, Van Elderen T, van der Kamp L, Oldridge N. Quality of life after myocardial infarction: translation and validation of the MacNew questionnaire for a Dutch population. Qual Life Res. 2004;13(8):1483–8.CrossRef
12.
go back to reference Eder B, Hofmann P, von Duvillard SP, Brandt D, Schmid JP, Pokan R, et al. Early 4-week cardiac rehabilitation exercise training in elderly patients after heart surgery. J Cardiopulm Rehabil Prev. 2010;30(2):85–92.CrossRef Eder B, Hofmann P, von Duvillard SP, Brandt D, Schmid JP, Pokan R, et al. Early 4-week cardiac rehabilitation exercise training in elderly patients after heart surgery. J Cardiopulm Rehabil Prev. 2010;30(2):85–92.CrossRef
13.
go back to reference Emmert MY, Salzberg SP, Theusinger OM, Felix C, Plass A, Hoerstrup SP, et al. How good patient blood management leads to excellent outcomes in Jehovah's witness patients undergoing cardiac surgery. Interact Cardiovasc Thorac Surg. 2011;12(2):183–8.CrossRef Emmert MY, Salzberg SP, Theusinger OM, Felix C, Plass A, Hoerstrup SP, et al. How good patient blood management leads to excellent outcomes in Jehovah's witness patients undergoing cardiac surgery. Interact Cardiovasc Thorac Surg. 2011;12(2):183–8.CrossRef
14.
go back to reference Jassar AS, Ford PA, Haber HL, Isidro A, Swain JD, Bavaria JE, et al. Cardiac surgery in Jehovah's witness patients: ten-year experience. Ann Thorac Surg. 2012;93(1):19–25.CrossRef Jassar AS, Ford PA, Haber HL, Isidro A, Swain JD, Bavaria JE, et al. Cardiac surgery in Jehovah's witness patients: ten-year experience. Ann Thorac Surg. 2012;93(1):19–25.CrossRef
15.
go back to reference Marshall L, Krampl C, Vrtik M, Haluska B, Griffin R, Mundy J, et al. Short term outcomes after cardiac surgery in a Jehovah's witness population: an institutional experience. Heart Lung Circ. 2012;21(2):101–4.CrossRef Marshall L, Krampl C, Vrtik M, Haluska B, Griffin R, Mundy J, et al. Short term outcomes after cardiac surgery in a Jehovah's witness population: an institutional experience. Heart Lung Circ. 2012;21(2):101–4.CrossRef
16.
go back to reference Vaislic CD, Dalibon N, Ponzio O, Ba M, Jugan E, Lagneau F, et al. Outcomes in cardiac surgery in 500 consecutive Jehovah's witness patients: 21 year experience. J Cardiothorac Surg. 2012;27(7):95.CrossRef Vaislic CD, Dalibon N, Ponzio O, Ba M, Jugan E, Lagneau F, et al. Outcomes in cardiac surgery in 500 consecutive Jehovah's witness patients: 21 year experience. J Cardiothorac Surg. 2012;27(7):95.CrossRef
Metadata
Title
Long-term survival and quality of life in Jehovah’s witnesses after cardiac surgery: a case control study
Authors
Pierre Wauthy
Charalampos Pierrakos
Louis Chebli
Redente Tortora
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2019
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-019-1061-z

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