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Open Access 01-12-2018 | Research article

“As du Coeur” study: a randomized controlled trial on quality of life impact and cost effectiveness of a physical activity program in patients with cardiovascular disease

Authors: Laurent Bailly, Philippe Mossé, Stéphane Diagana, Marion Fournier, Fabienne d’Arripe-Longueville, Odile Diagana, Jocelyn Gal, Jean Grebet, Mario Moncada, Jean-Jacques Domerego, Rémi Radel, Roxane Fabre, Alain Fuch, Christian Pradier

Published in: BMC Cardiovascular Disorders | Issue 1/2018

Abstract

Background

Physical activity programs (PAP) in patients with cardiovascular disease require evidence of cost-utility. To assess improvement in health-related quality of life (QoL) and reduction of health care consumption of patients following PAP, a randomized trial was used.

Methods

Patients from a health insurance company who had experienced coronary artery disease or moderate heart failure were invited to participate (N = 1891). Positive responders (N = 50) were randomly assigned to a progressively autonomous physical activity (PAPA) program or to a standard supervised physical activity (SPA) program. The SPA group had two supervised sessions per week over 5 months. PAPA group had one session per week and support to aid habit formation (written tips, exercise program, phone call). To measure health-related quality of life EQ-5D utility score were used, before intervention, 6 months (T6) and 1 year later. Health care costs were provided from reimbursement databases.

Results

Mobility, usual activities and discomfort improved significantly in both group (T6). One year later, EQ-5D utility score was improved in the PAPA group only. Total health care consumption in the intervention group decreased, from a mean of 4097 euros per year before intervention to 2877 euros per year after (p = 0.05), compared to a health care consumption of 4087 euros and 4180 euros per year, in the total population of patients (N = 1891) from the health insurance company. The incremental cost effectiveness ratio was 10,928 euros per QALYs.

Conclusion

A physical activity program is cost-effective in providing a better quality of life and reducing health care consumption in cardiovascular patients.

Trial registration

ISRCTN77313697, retrospectively registered on 20 November 2015.

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Title: “As du Coeur” study: a randomized controlled trial on quality of life impact and cost effectiveness of a physical activity program in patients with cardiovascular disease
Authors: Laurent Bailly
Philippe Mossé
Stéphane Diagana
Marion Fournier
Fabienne d’Arripe-Longueville
Odile Diagana
Jocelyn Gal
Jean Grebet
Mario Moncada
Jean-Jacques Domerego
Rémi Radel
Roxane Fabre
Alain Fuch
Christian Pradier
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Cardiovascular Disorders / Issue 1/2018
Electronic ISSN: 1471-2261
DOI: https://doi.org/10.1186/s12872-018-0973-3

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“As du Coeur” study: a randomized controlled trial on quality of life impact and cost effectiveness of a physical activity program in patients with cardiovascular disease

Abstract

Background

Methods

Results

Conclusion

Trial registration

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Abstract

Background

Methods

Results

Conclusion

Trial registration

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