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Published in: BMC Cardiovascular Disorders 1/2017

Open Access 01-12-2017 | Research article

Gender based differences in drug eluting stent implantation - data from the German ALKK registry suggest underuse of DES in elderly women

Authors: Martin A. Russ, Christian Wackerl, Uwe Zeymer, Matthias Hochadel, Sebastian Kerber, Ralf Zahn, Bernhard Zrenner, Hubert Topp, Volker Schächinger, Michael A. Weber, for the ALKK-Study Group

Published in: BMC Cardiovascular Disorders | Issue 1/2017

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Abstract

Background

Observational studies suggest there are gender based differences in the treatment of coronary artery disease, with women receiving evidence based therapy less frequently than suggested by current guidelines. The aim of our study was to evaluate gender based differences in the use of DES.

Methods

We analysed prospectively collected data from 100704 stent implantations in the PCI registry of the ALKK between 2005 and 2009.

Results

The usage of DES increased from 16.0 to 43.9%. Although women had smaller vessel sizes, they received DES less often compared to men (28.2 vs. 31.3%), with an adjusted odds ratio of 0.93 (95% confidence interval 0.89-0.97) at the age of 75, and an adjusted odds ratio of 0.89 (95% confidence interval 0.84-0.94) at the age of 80.

Conclusion

Despite having smaller vessels than men, women were treated less often with DES. These findings apply to women above the age of 75 years. These findings support previous reports, that elderly women with coronary artery disease are treated differently to men.
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Metadata
Title
Gender based differences in drug eluting stent implantation - data from the German ALKK registry suggest underuse of DES in elderly women
Authors
Martin A. Russ
Christian Wackerl
Uwe Zeymer
Matthias Hochadel
Sebastian Kerber
Ralf Zahn
Bernhard Zrenner
Hubert Topp
Volker Schächinger
Michael A. Weber
for the ALKK-Study Group
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2017
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-017-0500-y

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