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Published in: BMC Anesthesiology 1/2015

Open Access 01-12-2015 | Research article

Accuracy of an autocalibrated pulse contour analysis in cardiac surgery patients: a bi-center clinical trial

Authors: Ole Broch, Jose Carbonell, Carlos Ferrando, Malte Metzner, Arne Carstens, Martin Albrecht, Matthias Gruenewald, Jan Höcker, Marina Soro, Markus Steinfath, Jochen Renner, Berthold Bein

Published in: BMC Anesthesiology | Issue 1/2015

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Abstract

Background

Less-invasive and easy to install monitoring systems for continuous estimation of cardiac index (CI) have gained increasing interest, especially in cardiac surgery patients who often exhibit abrupt haemodynamic changes. The aim of the present study was to compare the accuracy of CI by a new semi-invasive monitoring system with transpulmonary thermodilution before and after cardiopulmonary bypass (CPB).

Methods

Sixty-five patients (41 Germany, 24 Spain) scheduled for elective coronary surgery were studied before and after CPB, respectively. Measurements included CI obtained by transpulmonary thermodilution (CITPTD) and autocalibrated semi-invasive pulse contour analysis (CIPFX). Percentage changes of CI were also calculated.

Results

There was only a poor correlation between CITPTD and CIPFX both before (r 2 = 0.34, p < 0.0001) and after (r 2 = 0.31, p < 0.0001) CPB, with a percentage error (PE) of 62 and 49 %, respectively. Four quadrant plots revealed a concordance rate over 90 % indicating an acceptable correlation of trends between CITPTD and CIPFX before (concordance: 93 %) and after (concordance: 94 %) CPB. In contrast, polar plot analysis showed poor trending before and an acceptable trending ability of changes in CI after CPB.

Conclusions

Semi-invasive CI by autocalibrated pulse contour analysis showed a poor ability to estimate CI compared with transpulmonary thermodilution. Furthermore, the new semi-invasive device revealed an acceptable trending ability for haemodynamic changes only after CPB.

Trial registration

ClinicalTrials.gov: NCT02312505 Date: 12.03.2012
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Metadata
Title
Accuracy of an autocalibrated pulse contour analysis in cardiac surgery patients: a bi-center clinical trial
Authors
Ole Broch
Jose Carbonell
Carlos Ferrando
Malte Metzner
Arne Carstens
Martin Albrecht
Matthias Gruenewald
Jan Höcker
Marina Soro
Markus Steinfath
Jochen Renner
Berthold Bein
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2015
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-015-0153-2

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