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Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie 5/2014

01-05-2014 | Review Article/Brief Review

Semi-invasive measurement of cardiac output based on pulse contour: a review and analysis

Authors: Thomas Schlöglhofer, BSc, Hermann Gilly, PhD, Heinrich Schima, PhD

Published in: Canadian Journal of Anesthesia/Journal canadien d'anesthésie | Issue 5/2014

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Abstract

Purpose

The aim of this review was to provide a meta-analysis of all five of the most popular systems for arterial pulse contour analysis compared with pulmonary artery thermodilution, the established reference method for measuring cardiac output (CO). The five investigated systems are FloTrac/Vigileo®, PiCCO®, LiDCO/PulseCO®, PRAM/MostCare®, and Modelflow.

Source

In a comprehensive literature search through MEDLINE®, Web of Knowledge (v.5.11), and Google Scholar, we identified prospective studies and reviews that compared the pulse contour approach with the reference method (n = 316). Data extracted from the 93 selected studies included range and mean cardiac output, bias, percentage error, software versions, and study population. We performed a pooled weighted analysis of their precision in determining CO in various patient groups and clinical settings.

Principal findings

Results of the majority of studies indicate that the five investigated systems show acceptable accuracy during hemodynamically stable conditions. Forty-three studies provided adequate data for a pooled weighted analysis and resulted in a mean (SD) total pooled bias of −0.28 (1.25) L·min−1, percentage error of 40%, and a correlation coefficient of r = 0.71. In hemodynamically unstable patients (n = 8), we found a higher percentage error (45%) and bias of −0.54 (1.64) L·min−1.

Conclusion

During hemodynamic instability, CO measurement based on continuous arterial pulse contour analysis shows only limited agreement with intermittent bolus thermodilution. The calibrated systems seem to deliver more accurate measurements than the auto-calibrated or the non-calibrated systems. For reliable use of these semi-invasive systems, especially for critical therapeutic decisions during hemodynamic disorders, both a strategy for hemodynamic optimization and further technological improvements are necessary.
Appendix
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Footnotes
1
Hatib F, Roteliuk L, Pearce J (inventors). Pulse contour method and apparatus for continuous assessment of a cardiovascular parameter. International patent publication WO 2006/113337 A2, 2006 Oct. 26.
 
2
Roteliuk L (inventor). Arterial pressure-based automatic determination of a cardiovascular parameter. International patent publication WO2005/055825 A1, 2005 June 23.
 
3
LiDCO Ltd. User’s Manual LiDCO Rapid-Fluid management just got easier. http://​www.​lidcorapid.​co.​uk/​pdfs/​english-rapid-v1.​04-user-manual.​pdf (accessed February 2014).
 
4
Edwards. Lifesciences Inc. FloTrac System 3rd Generation Software. Available from URL: http://​www.​edwards.​com/​eu/​products/​mininvasive/​Pages/​flotrac3g.​aspx (accessed February 2014).
 
6
Edwards Lifesciences Inc. EV1000 Clinical Platform 510(k) Summary. Available from URL: http://​www.​accessdata.​fda.​gov/​cdrh_​docs/​pdf10/​K100709.​pdf (accessed February 2014).
 
7
Joeken S, Fahle M, Pfeiffer UJ (inventors). Devices for in-vivo determination of the compliance function and the systemic blood flow of a living being. US patent US 6315735 B1.
 
8
Band DM, Linton RA, O’Brien TK (inventors). Method and apparatus for the measurement of cardiac output. International patent publication WO 97/24982 A.
 
9
Band MS, Linton WM, Linton RA, O’Brien KT (inventors). Verfahren und Vorrichtung zum Messen der Herzleistung. DE patent 697 23 847 T2. 2004 Jun. 03.
 
10
Romano S (inventor). Method and apparatus for measuring cardiac output. US patent US 6758822 B2.
 
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Metadata
Title
Semi-invasive measurement of cardiac output based on pulse contour: a review and analysis
Authors
Thomas Schlöglhofer, BSc
Hermann Gilly, PhD
Heinrich Schima, PhD
Publication date
01-05-2014
Publisher
Springer US
Published in
Canadian Journal of Anesthesia/Journal canadien d'anesthésie / Issue 5/2014
Print ISSN: 0832-610X
Electronic ISSN: 1496-8975
DOI
https://doi.org/10.1007/s12630-014-0135-8

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